CRYL1 (NM_015974) Human Untagged Clone

CAT#: SC317486

CRYL1 (untagged)-Human crystallin, lambda 1 (CRYL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CRYL1
• Synonyms: GDH; gul3DH; HEL30; lambda-CRY
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015974, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGTCCTCCGCGGCCGGCTGCGTGGTGATCGTTGGCAGTGGAGTCATTGGGCGAAGCTGGGCCATGC
  TGTTTGCCAGTGGAGGCTTCCAGGTGAAACTCTATGACATTGAGCAACAGCAGATAAGGAACGCCCTGGA
  AAACATCAGAAAGGAGATGAAGTTGCTGGAGCAGGCAGGTTCTCTGAAAGGCTCCCTGAGTGTGGAAGAG
  CAGCTGTCACTCATCAGTGGTTGTCCCAATATCCAAGAAGCAGTAGAGGGTGCCATGCACATTCAGGAAT
  GTGTTCCAGAAGATCTAGAACTGAAGAAGAAGATTTTTGCTCAGTTAGATTCCATCATTGATGATCGAGT
  GATCTTAAGCAGTTCCACTTCTTGTCTCATGCCTTCCAAGTTGTTTGCTGGCTTGGTCCATGTGAAGCAA
  TGCATCGTGGCTCATCCTGTGAATCCGCCATACTACATCCCGCTGGTTGAGCTGGTCCCCCACCCGGAGA
  CGGCCCCTACGACAGTGGACAGAACCCACGCCCTGATGAAGAAGATTGGACAGTGCCCCATGCGAGTCCA
  GAAGGAGGTGGCCGGCTTCGTTCTGAACCGCCTGCAATATGCAATCATCAGCGAGGCCTGGCGGCTAGTG
  GAGGAAGGAATCGTGTCTCCTAGTGACCTGGACCTTGTCATGTCAGAAGGGTTGGGCATGCGGTATGCAT
  TCATTGGACCCCTGGAAACCATGCATCTCAATGCAGAAGGTATGTTAAGCTACTGCGACAGATACAGCGA
  AGGCATAAAACATGTCCTACAGACTTTTGGACCCATTCCAGAGTTTTCCAGGGCCACTGCTGAGAAGGTT
  AACCAGGACATGTGCATGAAGGTCCCTGATGACCCGGAGCACTTAGCTGCCAGGAGGCAGTGGAGGGACG
  AGTGCCTCATGAGACTCGCCAAGTTGAAGAGTCAAGTGCAGCCCCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015974
• ORF Size: 960 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015974.2, NP_057058.2
• RefSeq Size: 1516
• RefSeq ORF: 960
• Locus ID: 51084
• Domains: 3HCDH, 3HCDH_N
• Gene Summary: The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye. [provided by RefSeq, Jul 2008]