SUCLG1 (NM_003849) Human Untagged Clone

CAT#: SC317541

SUCLG1 (untagged)-Human succinate-CoA ligase, alpha subunit (SUCLG1), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SUCLG1
• Synonyms: GALPHA; MTDPS9; SUCLA1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003849, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCGCAACCCTTGCCGCTGCCGCTGACATCGCTACCATGGTCTCCGGCAGCAGCGGCCTCGCCGCCG
  CCCGTCTCCTGTCGCGCAGCTTCCTCCTGCCGCAGAATGGAATTCGGCATTGTTCCTACACAGCTTCTCG
  GCAACATCTCTATGTTGATAAAAATACAAAGATTATTTGCCAGGGTTTCACTGGCAAACAGGGCACCTTT
  CACAGCCAGCAGGCATTGGAATATGGCACCAAACTCGTTGGAGGAACCACTCCAGGGAAAGGAGGCCAGA
  CACATCTGGGCTTACCTGTCTTTAATACTGTGAAGGAGGCCAAAGAACAGACAGGAGCAACGGCTTCTGT
  CATTTATGTTCCTCCGCCTTTTGCTGCTGCTGCCATTAATGAAGCTATTGAGGCAGAAATTCCCTTGGTT
  GTGTGTATCACTGAAGGAATTCCCCAGCAGGACATGGTACGAGTCAAGCACAAACTGCTGCGCCAGGAAA
  AGACAAGGCTAATTGGGCCCAACTGCCCTGGAGTCATCAATCCTGGAGAATGTAAAATTGGCATCATGCC
  TGGCCATATTCACAAAAAAGGAAGGATTGGCATTGTGTCCAGATCTGGCACCCTGACTTATGAAGCAGTT
  CACCAAACAACGCAAGTTGGATTGGGGCAGTCTTTGTGCGTTGGCATTGGAGGTGATCCTTTTAATGGAA
  CAGATTTTATTGACTGCCTCGAAATCTTTTTGAACGATTCTGCCACAGAAGGCATCATATTGATTGGTGA
  AATTGGTGGTAATGCAGAAGAGAATGCTGCAGAATTTTTGAAGCAACATAATTCAGGTCCAAATTCCAAG
  CCTGTAGTGTCCTTCATTGCTGGTTTAACTGCTCCTCCTGGGAGAAGAATGGGTCATGCCGGGGCAATTA
  TTGCTGGAGGAAAAGGTGGAGCTAAAGAGAAGATCTCTGCCCTTCAGAGTGCAGGAGTTGTGGTCAGTAT
  GTCTCCTGCACAGCTGGGAACCACGATCTACAAGGAATTTGAAAAGAGGAAGATGCTATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_003849
• ORF Size: 1041 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003849.3, NP_003840.2
• RefSeq Size: 1475
• RefSeq ORF: 1041
• Locus ID: 8802
• Domains: CoA_binding, ligase-CoA
• Protein Pathways: Citrate cycle (TCA cycle), Metabolic pathways, Propanoate metabolism
• Gene Summary: This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]