TXNDC5 (NM_030810) Human Untagged Clone

CAT#: SC317697

TXNDC5 (untagged)-Human thioredoxin domain containing 5 (endoplasmic reticulum) (TXNDC5), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TXNDC5
• Synonyms: ENDOPDI; ERP46; HCC-2; HCC2; PDIA15; STRF8; UNQ364
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_030810 edited
  CCCAGCCCCGCCGCGATGCCCGCGCGCCCAGGACGCCTCCTCCCGCTGCTGGCCCGGCCG
  GCGGCCCTGACTGCGCTGCTGCTGCTGCTGCTGGGCCATGGCGGCGGCGGGCGCTGGGGC
  GCCCGGGCCCAGGAGGCGGCGGCGGCGGCGGCGGACGGGCCCCCCGCGGCAGACGGCGAG
  GACGGACAGGACCCGCACAGCAAGCACCTGTACACGGCCGACATGTTCACGCACGGGATC
  CAGAGCGCCGCGCACTTCGTCATGTTCTTCGCGCCCTGGTGTGGACACTGCCAGCGGCTG
  CAGCCGACTTGGAATGACCTGGGAGACAAATACAACAGCATGGAAGATGCCAAAGTCTAT
  GTGGCTAAAGTGGACTGCACGGCCCACTCCGACGTGTGCTCCGCCCAGGGGGTGCGAGGA
  TACCCCACCTTAAAGCTTTTCAAGCCAGGCCAAGAAGCTGTGAAGTACCAGGGTCCTCGG
  GACTTCCAGACACTGGAAAACTGGATGCTGCAGACACTGAACGAGGAGCCAGTGACACCA
  GAGCCGGAAGTGGAACCGCCCAGTGCCCCCGAGCTCAAGCAAGGGCTGTATGAGCTCTCA
  GCAAGCAACTTTGAGCTGCACGTTGCACAAGGCGACCACTTTATCAAGTTCTTCGCTCCG
  TGGTGTGGTCACTGCAAAGCCCTGGCTCCAACCTGGGAGCAGCTGGCTCTGGGCCTTGAA
  CATTCCGAAACTGTCAAGATTGGCAAGGTTGATTGTACACAGCACTATGAACTCTGCTCC
  GGAAACCAGGTTCGTGGCTATCCCACTCTTCTCTGGTTCCGAGATGGGAAAAAGGTGGAT
  CAGTACAAGGGAAAGCGGGATTTGGAGTCACTGAGGGAGTACGTGGAGTCGCAGCTGCAG
  CGCACAGAGACTGGAGCGACGGAGACCGTCACGCCCTCAGAGGCCCCGGTGCTGGCAGCT
  GAGCCCGAGGCTGACAAGGGCACTGTGTTGGCACTCACTGAAAATAACTTCGATGACACC
  ATTGCAGAAGGAATAACCTTCATCAAGTTTTATGCTCCATGGTGTGGTCATTGTAAGACT
  CTGGCTCCTACTTGGGAGGAACTCTCTAAAAAGGAATTCCCTGGTCTGGCGGGGGTCAAG
  ATCGCCGAAGTAGACTGCACTGCTGAACGGAATATCTGCAGCAAGTATTCGGTACGAGGC
  TACCCCACGTTATTGCTTTTCCGAGGAGGGAAGAAAGTCAGTGAGCACAGTGGAGGCAGA
  GACCTTGACTCGTTACACCGCTTTGTCCTGAGCCAAGCGAAAGATGAACTTTAGGAACAC
  AGTTGGAGGTCACCTCTCCTGCCCAGCTCCCGCACCCTGCGTTTAGGAGTTCAGTCCCAC
  AGAGGCCACTGGGTTCCCAGTGGTGGCTGTTCAGAAAGCAGAACATACTAAGCGTGAGGT
  ATCTTCTTTGTGTGTGTGTTTTCCAAGCCAACACACTCTACAGATTCTTTATTAAGTTAA
  GTTTCTCTAAGTAAATGTGTAACTCATGGTCACTGTGTAAACATTTTCAGTGGCGATATA
  TCCCCTTTGACCTTCTCTTGATGAAATTTACATGGTTTCCTTTGAGACTAAAATAGCGTT
  GAGGGAAATGAAATTGCTGGACTATTTGTGGCTCCTGAGTTGAGTGATTTTGGTGAAAGA
  AAGCACATCCAAAGCATAGTTTACCTGCCCACGAGTTCTGGAAAGGTGGCCTTGTGGCAG
  TATTGACGTTCCTCTGATCTTAAGGTCACAGTTGACTCAATACTGTGTTGGTCCGTAGCA
  TGGAGCAGATTGAAATGCAAAAACCCACACCTCTGGAAGATACCTTCACGGCCGCTGCTG
  GAGCTTCTGTTGCTGTGAATACTTCTCTCAGTGTGAGAGGTTAGCCGTGATGAAAGCAGC
  GTTACTTCTGACCGTGCCTGAGTAAGAGAATGCTGATGCCATAACTTTATGTGTCGATAC
  TTGTCAAATCAGTTACTGTTCAGGGGATCCTTCTGTTTCTCACGGGGTGAAACATGTCTT
  TAGTTCCTCATGTTAACACGAAGCCAGAGCCCACATGAACTGTTGGATGTCTTCCTTAGA
  AAGGGTAGGCATGGAAAATTCCACGAGGCTCATTCTCAGTATCTCATTAACTCATTGAAA
  GATTCCAGTTGTATTTGTCACCTGGGGTGACAAGACCAGACAGGCTTTCCCAGGCCTGGG
  TATCCAGGGAGGCTCTGCAGCCCTGCTGAAGGGCCCTAACTAGAGTTCTAGAGTTTCTGA
  TTCTGTTTCTCAGTAGTCCTTTTAGAGGCTTGCTATACTTGGTCTGCTTCAAGGAGGTCG
  ACCTTCTAATGTATGAAGAATGGGATGCATTTGATCTCAAGACCAAAGACAGATGTCAGT
  GGGCTGCTCTGGCCCTGGTGTGCACGGCTGTGGCAGCTGTTGATGCCAGTGTCCTCTAAC
  TCATGCTGTCCTTGTGATTAAACACYTCTATCTCCCTTGGGAATAAGCACATACAGGCTT
  AAGCTCTAAGATAGATAGGTGTTTGTCCTTTTACCATCGAGCTACTTCCCATAATAACCA
  CTTTGCATCCAACACTCTTCACCCACCTCCCATACGCAAGGGGATGTGGATACTTGGCCC
  AAAGTAACTGGTGGTAGGAATCTTAGAAACAAGACCACTTATACTGTCTGTCTGAGGCAG
  AAGATAACAGCAGCATCTCGACCAGCCTCTGCCTTAAAGGAAATCTTTATTAATCACGTR
  TGGTTCACAGATAATTCTTTTTTTAAAAAAACCCAACCTCCTAGAGAAGCACAACTGTCA
  AGAGTCKKGTACACACAACTTCAGCTTCAGCTTTGCATCACGAGTCTTGTATTCCAAGAA
  AATCAAAGTGGTACAATTTGTTTGTTTACACTATGATACTTTCTAAATAAACTCTTTTTT
  TT
  
• Restriction Sites: Please inquire
• ACCN: NM_030810
• ORF Size: 1299 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_030810.2, NP_110437.2
• RefSeq Size: 2970
• RefSeq ORF: 1299
• Locus ID: 81567
• Domains: thiored
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).