TRIT1 (NM_017646) Human Untagged Clone

CAT#: SC317768

TRIT1 (untagged)-Human tRNA isopentenyltransferase 1 (TRIT1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIT1
• Synonyms: COXPD35; GRO1; hGRO1; IPPT; IPT; IPTase; MOD5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017646, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTAC
  CTCTTGTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCT
  CGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGGTCTATGAAGGCCTAGACATCATCACCAACAAGGTT
  TCTGCCCAAGAGCAGAGAATCTGCCGGCACCACATGATCAGCTTTGTGGATCCTCTTGTGACCAATTACA
  CAGTGGTGGACTTCAGAAATAGAGCAACTGCTCTGATTGAAGATATATTTGCCCGAGACAAAATTCCTAT
  TGTTGTGGGAGGAACCAATTATTACATTGAATCTCTGCTCTGGAAAGTTCTTGTCAATACCAAGCCCCAG
  GAGATGGGCACTGAGAAAGTGATTGACCGAAAAGTGGAGCTTGAAAAGGAGGATGGTCTTGTACTTCACA
  AACGCCTAAGCCAGGTGGACCCAGAAATGGCTGCCAAGCTGCATCCACATGACAAACGCAAAGTGGCCAG
  GAGCTTGCAAGTTTTTGAAGAAACAGGAATCTCTCATAGTGAATTTCTCCATCGTCAACATACGGAAGAA
  GGTGGTGGTCCCCTTGGAGGTCCTCTGAAGTTCTCTAACCCTTGCATCCTTTGGCTTCATGCTGACCAGG
  CAGTTCTAGATGAGCGCTTGGATAAGAGGGTGGATGACATGCTTGCTGCTGGGCTCTTGGAGGAACTAAG
  AGATTTTCACAGACGCTATAATCAGAAGAATGTTTCGGAAAATAGCCAGGACTATCAACATGGTATCTTC
  CAATCAATTGGCTTCAAGGAATTTCACGAGTACCTGATCACTGAGGGAAAATGCACACTGGAGACTAGTA
  ACCAGCTTCTAAAGAAAGGTATTGAGGCTCTGAAACAAGTAACTAAGAGATATGCCCGGAAACAAAACCG
  ATGGGTTAAAAACCGTTTTTTGAGCAGACCTGGTCCCATTGTCCCCCCTGTCTATGGCTTAGAGGTATCT
  GATGTCTCGAAGTGGGAAGAGTCTGTTCTTGAACCTGCTCTTGAAATCGTGCAAAGTTTCATCCAGGGCC
  ACAAGCCTACAGCCACTCCAATAAAGATGCCATACAATGAAGCTGAGAACAAGAGAAGTTATCACCTGTG
  TGACCTCTGTGATCGAATCATCATTGGGGATCGCGAATGGGCAGCGCACATAAAATCCAAATCCCACTTG
  AACCAACTGAAGAAAAGAAGAAGATTGGACTCAGATGCTGTCAACACCATAGAAAGTCAGAGTGTTTCCC
  CAGACCATAACAAAGAACCTAAAGAGAAGGGATCCCCAGGGCAGAATGATCAAGAGCTGAAATGCAGCGT
  TTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_017646
• ORF Size: 1404 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017646.5, NP_060116.2
• RefSeq Size: 2159
• RefSeq ORF: 1404
• Locus ID: 54802
• Domains: IPPT, ZnF_U1
• Protein Pathways: Metabolic pathways
• Gene Summary: This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]
  Transcript Variant: This variant (1) encodes the longest functional protein (isoform 1).