ATG4D (NM_032885) Human Untagged Clone

CAT#: SC317783

ATG4D (untagged)-Human ATG4 autophagy related 4 homolog D (S. cerevisiae) (ATG4D)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATG4D
• Synonyms: APG4-D; APG4D; AUTL4
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_032885, the custom clone sequence may differ by one or more nucleotides
  ATGAACTCAGTGTCGCCGGCCGCCGCGCAGTACCGGAGCAGCAGCCCGGAGGACGCGCGC
  CGCCGGCCCGAGGCCCGCAGGCCGCGGGGTCCCAGAGGCCCAGACCCCAACGGCCTGGGG
  CCTTCCGGAGCCAGCGGCCCCGCTCTTGGCTCTCCCGGGGCTGGCCCGAGTGAGCCGGAC
  GAAGTGGACAAGTTCAAGGCCAAGTTCCTGACAGCCTGGAACAACGTCAAGTACGGTTGG
  GTGGTTAAAAGCCGGACCAGCTTTAGCAAGATCTCCAGCATCCACCTCTGTGGCCGCCGC
  TACCGTTTCGAGGGCGAGGGTGACATACAGCGTTTCCAGCGGGACTTTGTGTCCCGCCTG
  TGGCTCACATACCGCCGGGACTTCCCGCCCCTTCCTGGGGGCTGCCTGACCTCGGACTGT
  GGCTGGGGGTGCATGTTACGCAGCGGCCAGATGATGCTGGCACAGGGCCTTCTGCTGCAT
  TTCCTGCCCAGAGACTGGACATGGGCCGAGGGCATGGGCCTGGGCCCCCCTGAGCTGTCA
  GGGTCAGCCTCTCCCAGCCGGTACCATGGGCCTGCCCGCTGGATGCCCCCACGCTGGGCC
  CAGGGTGCCCCTGAGCTGGAGCAGGAACGCCGGCACCGGCAGATTGTGTCCTGGTTCGCC
  GACCACCCCCGGGCCCCCTTTGGCCTACACCGGCTGGTGGAGCTTGGGCAGAGCTCAGGC
  AAGAAGGCAGGTGACTGGTATGGGCCATCGCTAGTGGCACACATCCTCAGGAAAGCCGTG
  GAGAGCTGCTCCGACGTCACCCGCCTGGTGGTGTACGTTTCTCAGGACTGCACAGTGTAC
  AAGGCGGATGTGGCACGCCTGGTGGCCAGGCCAGACCCCACAGCCGAGTGGAAGTCTGTG
  GTCATCCTGGTGCCCGTGCGACTGGGTGGCGAGACTCTCAACCCCGTGTATGTGCCCTGC
  GTGAAGGAACTCCTGCGTTGCGAGCTGTGCCTGGGCATCATGGGTGGGAAACCGCGACAC
  TCACTGTACTTCATTGGCTACCAAGATGACTTCCTGCTGTACCTGGACCCTCACTACTGC
  CAGCCCACTGTGGATGTCAGCCAGGCCGACTTCCCCCTGGAGTCCTTCCACTGCACCTCG
  CCCCGCAAGATGGCCTTTGCCAAGATGGACCCAAGCTGTACCGTGGGCTTCTATGCTGGA
  GACAGGAAGGAGTTTGAGACACTCTGCTCAGAGCTGACCAGGGTCCTCAGCTCCTCCTCA
  GCCACAGAGCGGTACCCCATGTTCACCCTGGCCGAGGGCCATGCTCAGGACCACAGCCTG
  GACGACCTCTGCTCCCAGCTCGCCCAGCCCACACTCCGGCTCCCTCGCACAGGGCGGCTC
  CTCAGGGCCAAACGCCCCAGCTCTGAGGACTTTGTGTTTTTA
  
• Restriction Sites: Please inquire
• ACCN: NM_032885
• ORF Size: 1425 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032885.4, NP_116274.3
• RefSeq Size: 1929
• RefSeq ORF: 1425
• Locus ID: 84971
• Domains: Peptidase_C54
• Protein Pathways: Regulation of autophagy
• Gene Summary: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) encodes the longer isoform (1).