CYP2R1 (NM_024514) Human Untagged Clone

CAT#: SC317844

CYP2R1 (untagged)-Human cytochrome P450, family 2, subfamily R, polypeptide 1 (CYP2R1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYP2R1
• Synonyms: MGC4663
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_024514, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGAAGCTTTGGAGAGCTGAAGAGGGCGCGGCGGCGCTCGGCGGCGCGCTCTTCCTGCTGCTCTTCG
  CGCTAGGGGTCCGCCAGCTGCTGAAGCAGAGGCGGCCGATGGGCTTCCCCCCGGGGCCGCCGGGGCTGCC
  ATTTATCGGCAACATCTATTCCCTGGCAGCCTCATCCGAGCTTCCCCATGTCTACATGAGAAAGCAGAGC
  CAGGTGTACGGAGAGATCTTCAGTTTAGATCTTGGAGGCATATCAACTGTGGTTCTAAATGGCTATGATG
  TAGTAAAGGAATGCCTTGTTCATCAAAGCGAAATTTTTGCAGACAGACCATGCCTTCCTTTATTCATGAA
  GATGACAAAAATGGGAGGCTTACTCAATTCCAGATATGGCCGAGGATGGGTTGATCACAGACGATTAGCT
  GTAAACAGTTTTCGATATTTTGGATATGGCCAAAAGTCTTTTGAATCTAAAATCTTGGAAGAAACCAAAT
  TTTTCAATGATGCTATTGAAACATACAAAGGTAGACCTTTTGACTTTAAACAGTTAATAACGAATGCTGT
  TTCAAACATAACCAATCTGATCATTTTTGGAGAACGATTCACTTATGAAGACACCGATTTTCAGCACATG
  ATTGAGTTATTTAGTGAAAATGTGGAACTAGCTGCCAGTGCCTCAGTCTTCTTGTATAATGCCTTTCCAT
  GGATTGGCATCCTGCCTTTTGGAAAACATCAACAGCTGTTTAGAAATGCAGCTGTAGTCTATGATTTTCT
  CTCCAGACTCATTGAAAAAGCTTCAGTCAACAGAAAGCCTCAGCTACCTCAGCATTTTGTTGATGCTTAT
  TTAGATGAGATGGATCAAGGTAAAAATGACCCATCATCTACTTTCTCCAAAGAAAACCTAATTTTCTCAG
  TGGGTGAACTCATCATTGCTGGAACTGAAACTACAACCAATGTGCTACGGTGGGCGATTCTTTTCATGGC
  CCTTTATCCTAATATTCAAGGACAAGTTCAGAAAGAGATTGATTTAATTATGGGCCCTAATGGGAAGCCT
  TCTTGGGACGACAAATGCAAAATGCCTTATACTGAGGCAGTTTTGCATGAAGTTTTAAGATTCTGTAATA
  TAGTTCCATTAGGGATTTTCCATGCAACCTCTGAAGATGCAGTTGTACGTGGTTATTCCATTCCTAAAGG
  CACAACAGTAATTACAAATCTTTATTCTGTACACTTTGATGAAAAGTACTGGAGAGACCCAGAAGTGTTC
  CATCCTGAGCGATTTCTGGACAGCAGTGGATATTTTGCCAAGAAGGAAGCTTTGGTTCCTTTTTCCCTAG
  GAAGAAGACATTGTCTTGGAGAACACTTGGCTCGGATGGAAATGTTCTTGTTTTTTACAGCATTGCTTCA
  GAGGTTTCATTTGCATTTTCCACATGAACTAGTTCCAGATCTGAAGCCCAGGTTAGGCATGACATTGCAG
  CCCCAACCCTACCTCATCTGTGCTGAAAGACGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_024514
• ORF Size: 1506 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_024514.4, NP_078790.2
• RefSeq Size: 1633
• RefSeq ORF: 1506
• Locus ID: 120227
• Protein Families: Druggable Genome, P450, Transmembrane
• Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]