DOK7 (NM_173660) Human Untagged Clone

CAT#: SC317850

DOK7 (untagged)-Human docking protein 7 (DOK7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DOK7
• Synonyms: C4orf25; CMS1B; CMS10; FADS3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_173660, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCGAGGCGGCGCTGGTGGAGGGCCAGGTCAAGCTGCGGGACGGCAAGAAGTGGAAGAGTAGGTGGC
  TGGTGCTGCGGAAGCCGTCGCCCGTGGCAGACTGCCTGCTGATGCTGGTCTACAAGGACAAGTCGGAGCG
  TATCAAGGGCCTGCGGGAGCGCAGCAGCCTGACGCTAGAGGACATCTGCGGGCTGGAGCCCGGCCTGCCC
  TACGAGGGCCTGGTCCACACGCTGGCCATTGTCTGCCTGTCCCAGGCCATCATGCTGGGCTTTGACAGCC
  ACGAGGCCATGTGTGCGTGGGATGCCCGGATCCGCTATGCGCTCGGCGAGGTGCATAGGTTCCATGTGAC
  AGTGGCTCCAGGCACCAAGTTGGAGAGCGGCCCGGCTACCCTGCACCTCTGCAATGATGTCCTCGTCTTG
  GCCAGGGACATCCCCCCGGCTGTCACGGGGCAGTGGAAGCTGTCTGACCTCCGGCGCTACGGGGCCGTGC
  CAAGCGGATTCATCTTTGAAGGCGGGACCAGGTGTGGGTACTGGGCTGGCGTCTTCTTCCTGTCCTCGGC
  CGAGGGGGAGCAGATCAGCTTCCTGTTCGACTGCATCGTCCGAGGCATCTCCCCCACCAAGGGCCCCTTT
  GGGCTGCGGCCGGTTCTACCAGACCCAAGTCCCCCGGGACCCTCGACTGTGGAGGAGCGTGTGGCCCAGG
  AAGCCCTGGAAACCCTACAGCTGGAGAAGCGGCTGAGCCTCCTCTCACATGCGGGCAGGCCGGGCAGTGG
  AGGGGATGACCGCAGCCTGTCCAGCTCATCCTCAGAGGCCAGTCACTTGGACGTCAGCGCCAGCAGCCGG
  CTCACCGCATGGCCAGAGCAATCCTCGTCGTCAGCCAGCACGTCACAGGAGGGGCCTAGACCAGCAGCTG
  CCCAGGCCGCCGGGGAAGCCATGGTGGGTGCCTCAAGGCCACCCCCCAAGCCGCTGCGTCCGCGGCAGCT
  GCAGGAGGTTGGCCGCCAGAGCTCCTCGGACAGCGGCATCGCCACTGGCAGCCACTCCTCTTACTCCAGC
  AGCCTCTCGTCCTACGCGGGCAGCAGCCTGGACGTGTGGCGGGCCACAGATGAACTGGGCTCACTGCTCA
  GCCTGCCAGCAGCGGGGGCCCCCGAGCCCAGCCTGTGCACCTGCCTGCCCGGGACAGTCGAGTACCAGGT
  GCCCACCTCCCTGCGGGCCCACTATGACACACCACGCAGCCTTTGCCTGGCTCCTAGAGACCACAGCCCC
  CCCTCACAGGGCAGCCCCGGCAACAGTGCGGCCAGGGACTCAGGCGGCCAGACGTCCGCCGGGTGTCCCT
  CTGGCTGGCTGGGCACGAGACGGCGGGGCCTGGTGATGGAGGCCCCCCAGGGCAGCGAGGCCACACTGCC
  TGGCCCTGCCCCTGGCGAGCCCTGGGAAGCAGGCGGCCCCCACGCGGGGCCACCCCCGGCTTTCTTTTCG
  GCATGTCCAGTCTGTGGAGGACTCAAGGTAAACCCCCCTCCTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_173660
• ORF Size: 1515 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_173660.4, NP_775931.3
• RefSeq Size: 2583
• RefSeq ORF: 1515
• Locus ID: 285489
• Gene Summary: The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
  Transcript Variant: This variant (1) differs in the 3' UTR and coding sequence compared to variant 4. The resulting isoform (1) has a shorter and distinct C-terminus compared to isoform 4.