Gliomedin (GLDN) (NM_181789) Human Untagged Clone

CAT#: SC317941

GLDN (untagged)-Human gliomedin (GLDN)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GLDN
• Synonyms: CLOM; COLM; CRG-L2; CRGL2; LCCS11; UNC-112
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_181789, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCGAGGCGCTGAGGGAGGCCGTGGGGACGCGGGTTGGGGCCTGCGTGGCGCCCTGGCGGCCGTGG
  CGCTGCTCTCGGCGCTCAACGCTGCGGGCACGGTGTTCGCGCTGTGCCAGTGGCGCGGGCTGAGCTCGGC
  GCTGCGGGCTTTGGAGGCGCAGCGGGGCCGGGAGCAGCGCGAGGACAGTGCCCTGCGCTCCTTCCTGGCC
  GAGTTGAGCCGCGCGCCGCGCGGGGCGTCCGCACCACCCCAAGACCCGGCCAGCTCAGCTCGCAACAAGC
  GCAGCCACAGCGGCGAGCCCGCGCCGCATATCCGCGCCGAGAGCCATGACATGCTGATGATGATGACCTA
  CTCCATGGTGCCGATCCGAGTGATGGTGGACCTGTGCAACAGCACCAAGGGCATCTGCCTCACAGGACCT
  TCTGGACCACCAGGACCTCCGGGAGCCGGCGGGTTGCCAGGACACAACGGATTGGATGGACAGCCTGGTC
  CTCAGGGCCCAAAAGGAGAAAAAGGAGCAAATGGAAAAAGAGGAAAAATGGGGATACCTGGAGCTGCAGG
  AAATCCAGGGGAAAGGGGAGAAAAGGGAGACCATGGTGAACTGGGCCTGCAGGGAAATGAGGGCCCACCA
  GGGCAGAAGGGAGAAAAGGGTGACAAAGGAGATGTGTCCAACGACGTGCTCCTGGCAGGTGCCAAAGGTG
  ACCAAGGCCCACCCGGTCCACCTGGGCCCCCAGGCCCTCCAGGTCCTCCAGGGCCCCCTGGAAGCAGAAG
  AGCCAAAGGCCCTCGGCAGCCAAGCATGTTCAACGGCCAGTGCCCAGGTGAGACTTGTGCCATACCAAAT
  GATGATACCTTGGTTGGAAAAGCTGATGAGAAAGCCAGTGAACACCATTCCCCACAAGCAGAATCCATGA
  TCACTTCCATTGGAAACCCAGTGCAAGTACTGAAAGTGACAGAGACATTTGGGACTTGGATAAGAGAGTC
  TGCTAACAAGAGTGATGACCGGATTTGGGTGACAGAGCATTTTTCAGGCATCATGGTTAAGGAATTCAAG
  GATCAGCCCTCACTTCTGAATGGCAGTTACACGTTCATCCACCTTCCATACTATTTCCATGGCTGTGGGC
  ACGTTGTTTACAACAACTCTCTCTACTACCACAAAGGGGGTTCTAATACCCTAGTGAGATTTGAATTTGG
  CCAGGAAACATCCCAAACTCTGAAGCTTGAAAATGCCTTGTATTTTGATCGAAAATACCTTTTTGCAAAT
  TCCAAAACTTACTTCAATCTAGCTGTAGATGAAAAGGGCCTTTGGATTATCTATGCGTCAAGTGTGGACG
  GCTCGAGCATTCTTGTAGCACAACTGGATGAGAGGACATTCTCAGTGGTGCAACACGTCAATACCACGTA
  CCCTAAATCCAAGGCTGGCAACGCCTTCATTGCCCGAGGAATCCTCTATGTCACAGACACCAAAGATATG
  AGGGTCACATTTGCCTTTGATTTGTTAGGAGGGAAACAGATCAATGCAAACTTTGATTTAAGAACTTCCC
  AGTCTGTTCTTGCCATGTTAGCATACAACATGAGAGATCAGCATTTATATTCATGGGAAGATGGCCATTT
  AATGCTTTATCCTGTGCAGTTTTTGTCAACTACCTTAAATCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_181789
• ORF Size: 1656 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_181789.2, NP_861454.2
• RefSeq Size: 5084
• RefSeq ORF: 1656
• Locus ID: 342035
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1), which undergoes proteolytic processing to generate a secreted form of the protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.