SH3BP1 (NM_018957) Human Untagged Clone

CAT#: SC318179

SH3BP1 (untagged)-Human SH3-domain binding protein 1 (SH3BP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SH3BP1
• Synonyms: ARHGAP43
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018957, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATGAAGAGGCAGCTGCACCGCATGCGGCAGCTGGCCCAGACGGGCAGCTTGGGACGCACCCCGGAGA
  CCGCTGAGTTCCTGGGTGAGGACCTGCTGCAGGTAGAACAGCGGCTGGAGCCGGCCAAGCGGGCAGCCCA
  CAACATCCACAAGCGGCTGCAGGCCTGTCTGCAGGGCCAGAGCGGGGCAGACATGGACAAGCGGGTGAAG
  AAGCTTCCCCTCATGGCTCTGTCCACCACGATGGCTGAGAGCTTCAAGGAGCTGGACCCTGATTCCAGCA
  TGGGGAAGGCCTTGGAGATGAGCTGTGCCATCCAGAATCAGCTGGCCCGCATCCTGGCCGAGTTTGAGAT
  GACCCTGGAGAGGGACGTCCTGCAGCCACTCAGCAGGCTGAGTGAGGAGGAGCTGCCAGCCATCCTCAAA
  CACAAGAAAAGCCTCCAGAAGCTCGTGTCCGACTGGAACACACTCAAGAGCAGGCTCAGTCAGGCAACCA
  AGAATTCAGGCAGCAGTCAAGGCCTAGGAGGCAGCCCGGGTAGTCACAGCCATACGACCATGGCCAACAA
  GGTGGAGACGCTGAAGGAGGAGGAGGAGGAGCTGAAGAGGAAAGTGGAGCAATGCAGGGACGAGTACTTG
  GCTGACCTGTACCACTTTGTTACCAAGGAGGACTCCTATGCCAACTACTTCATTCGTCTCCTGGAGATTC
  AGGCCGATTACCATCGCAGGTCACTGAGCTCGCTGGACACAGCCCTGGCTGAGCTGAGGGAGAACCACGG
  CCAAGCAGACCACTCCCCTTCGATGACAGCCACCCACTTCCCCAGGGTGTATGGGGTGTCGCTGGCAACC
  CACCTGCAAGAGCTGGGCCGGGAGATTGCCCTGCCCATCGAGGCCTGCGTCATGATGCTGCTTTCTGAGG
  GCATGAAGGAAGAGGGTCTCTTCCGTCTGGCTGCTGGGGCCTCGGTGCTGAAGCGTCTCAAGCAGACAAT
  GGCCTCGGACCCCCACAGCCTGGAGGAGTTCTGCTCCGACCCGCACGCTGTGGCAGGTGCCCTCAAGTCC
  TATCTGCGGGAGCTGCCAGAGCCTCTGATGACCTTCGACCTCTATGATGACTGGATGAGGGCAGCCAGCC
  TGAAGGAGCCAGGGGCCCGGCTGCAGGCCCTCCAAGAGGTGTGCAGCCGCCTACCCCCCGAGAACCTCAG
  CAACCTCAGGTACCTGATGAAGTTCCTGGCACGGCTGGCCGAGGAGCAGGAGGTGAACAAGATGACACCC
  AGCAACATCGCCATAGTCCTGGGACCCAACTTGCTGTGGCCACCTGAGAAAGAAGGGGACCAGGCCCAGC
  TGGATGCAGCCTCCGTGTCTTCCATCCAGGTGGTGGGCGTCGTCGAGGCGCTGATCCAGAGCGCAGACAC
  CCTCTTCCCTGGAGACATCAACTTCAACGTGTCAGGCCTCTTCTCAGCTGTTACCCTCCAGGACACAGTC
  AGTGACAGGCTGGCCTCTGAGGAACTTCCGTCCACTGCCGTGCCCACCCCAGCCACCACCCCGGCTCCGG
  CTCCGGCTCCAGCTCCAGCTCCGGCCCCAGCCTTGGCTTCAGCAGCTACCAAGGAAAGGACAGAGTCTGA
  GGTGCCTCCCAGACCAGCCTCCCCCAAGGTCACCAGGAGTCCCCCGGAGACAGCTGCCCCAGTGGAGGAC
  ATGGCTCGGAGGACCAAGCGCCCGGCGCCAGCCCGGCCCACCATGCCGCCCCCCCAGGTCTCCGGCTCCC
  GCTCCTCCCCTCCAGCCCCGCCCTTGCCCCCTGGCTCTGGCAGCCCTGGGACCCCCCAAGCCCTGCCCCG
  ACGTCTGGTTGGCAGCAGCCTCCGAGCCCCCACAGTGCCACCCCCGTTACCCCCCACACCCCCTCAGCCT
  GCCCGGCGCCAAAGCCGGCGTTCACCAGCCTCCCCCAGCCCGGCCTCCCCAGGTCCAGCCTCCCCCAGCC
  CAGTCTCTTTGAGTAACCCTGCACAGGTGGACCTGGGGGCTGCCACAGCAGAGGGAGGAGCCCCTGAGGC
  TATCAGTGGGGTCCCCACTCCCCCAGCTATCCCCCCTCAGCCCCGCCCCAGGAGCCTTGCCTCAGAGACC
  AACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_018957
• ORF Size: 2106 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018957.3, NP_061830.3
• RefSeq Size: 2592
• RefSeq ORF: 2106
• Locus ID: 23616
• Domains: RhoGAP
• Gene Summary: This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).