SF3B2 (NM_006842) Human Untagged Clone

CAT#: SC318368

SF3B2 (untagged)-Human splicing factor 3b, subunit 2, 145kDa (SF3B2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SF3B2
• Synonyms: Cus1; SAP145; SF3b1; SF3B145; SF3b150
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006842, the custom clone sequence may differ by one or more nucleotides
  ATGGCGACGGAGCATCCCGAGCCTCCCAAAGCAGAATTGCAGCTGCCGCCGCCGCCACCT
  CCAGGCCACTATGGCGCCTGGGCTGCCCAGGAGCTTCAGGCCAAGTTGGCAGAGATCGGA
  GCTCCGATCCAGGGTAATCGCGAGGAGCTGGTGGAGCGGCTGCAGAGCTACACCCGCCAG
  ACTGGCATCGTGCTGAATCGGCCGGTTTTGAGAGGGGAAGATGGGGACAAAGCCGCTCCA
  CCTCCCATGTCGGCACAGCTCCCTGGAATTCCCATGCCACCACCACCTTTGGGACTCCCC
  CCTCTGCAGCCTCCTCCGCCACCCCCACCACCTCCACCAGGCCTTGGCCTTGGCTTTCCT
  ATGGCCCACCCACCAAATTTGGGGCCCCCGCCTCCTCTCCGTGTGGGTGAGCCAGTGGCA
  CTGTCAGAGGAGGAGCGGCTGAAGTTGGCTCAGCAGCAGGCGGCATTGCTGATGCAGCAG
  GAGGAGCGTGCCAAGCAGCAGGGAGATCATTCGCTGAAGGAACATGAGCTCTTGGAGCAG
  CAGAAGCGGGCAGCTGTGTTACTGGAGCAGGAACGACAGCAGGAGATTGCCAAGATGGGC
  ACCCCAGTCCCTCGGCCCCCACAAGACATGGGCCAGATTGGTGTGCGCACTCCTCTGGGT
  CCTCGAGTAGCTGCTCCAGTGGGCCCAGTGGGCCCCACTCCTACAGTTTTGCCCATGGGA
  GCCCCTGTTCCCCGGCCTCGTGGTCCCCCACCGCCCCCTGGAGATGAGAACAGAGAGATG
  GATGACCCCTCTGTGGGCCCCAAGATCCCCCAGGCTTTGGAGAAGATCCTGCAGCTGAAG
  GAGAGCCGCCAGGAAGAGATGAATTCTCAGCAGGAGGAAGAGGAAATGGAAACAGATGCT
  CGCTCGTCCCTGGGCCAGTCAGCGTCAGAGACTGAGGAGGACACAGTGTCCGTATCTAAA
  AAGGAGAAAAACCGGAAGCGTAGGAACCGAAAGAAGAAGAAAAAGCCCCAGCGGGTGCGA
  GGGGTGTCCTCTGAGAGCTCTGGGGACCGGGAGAAAGACTCAACCCGGTCCCGTGGCTCT
  GATTCCCCAGCAGCTGATGTTGAGATTGAGTATGTGACTGAAGAACCTGAAATTTACGAG
  CCCAACTTTATCTTCTTTAAGAGGATCTTTGAGGCTTTTAAGCTCACTGATGATGTGAAG
  AAGGAGAAAGAGAAGGAGCCAGAGAAACTTGACAAACTGGAGAACTCTGCAGCCCCCAAG
  AAGAAGGGATTTGAAGAGGAGCACAAGGACAGTGATGATGACAGCAGTGATGACGAGCAG
  GAAAAGAAGCCAGAAGCCCCCAAGCTGTCCAAGAAGAAGTTGCGCCGAATGAACCGCTTC
  ACTGTGGCTGAACTCAAGCAGCTGGTGGCTCGGCCCGATGTCGTGGAGATGCACGATGTG
  ACAGCGCAGGACCCTAAGCTCTTGGTTCACCTCAAGGCCACTCGGAACTCTGTGCCTGTG
  CCACGCCACTGGTGTTTTAAGCGCAAATACCTGCAGGGCAAACGGGGCATTGAGAAGCCC
  CCCTTCGAGCTGCCAGACTTCATCAAACGCACAGGCATCCAGGAGATGCGAGAGGCCCTG
  CAGGAGAAGGAAGAACAGAAGACCATGAAGTCAAAAATGCGAGAGAAAGTTCGGCCTAAG
  ATGGGCAAAATTGACATCGACTACCAGAAACTGCATGATGCCTTCTTCAAGTGGCAGACC
  AAGCCAAAGCTGACCATCCATGGGGACCTGTACTATGAGGGGAAGGAGTTCGAGACACGA
  CTGAAGGAGAAGAAGCCAGGAGATCTGTCTGATGAGCTAAGGATTTCCTTGGGGATGCCA
  GTAGGACCAAATGCCCACAAGGTCCCTCCCCCATGGCTGATTGCCATGCAGCGATATGGA
  CCACCCCCATCGTATCCCAACCTGAAAATCCCTGGGCTGAACTCGCCCATCCCTGAGAGC
  TGTTCCTTTGGGTACCATGCTGGTGGCTGGGGCAAACCTCCAGTGGATGAGACTGGGAAA
  CCGCTCTATGGGGACGTGTTTGGAACCAATGCTGCTGAATTTCAGACCAAGACTGAGGAA
  GAAGAGATTGATCGGACCCCTTGGGGGGAACTGGAACCATCTGATGAAGAATCCTCAGAA
  GAAGAGGAAGAGGAAGAAAGTGATGAAGACAAACCAGATGAGACAGGCTTTATTACCCCT
  GCAGACAGTGGCCTTATCACTCCTGGAGGCTTTTCATCAGTGCCTGCTGGAATGGAGACC
  CCTGAACTCATTGAGCTGAGGAAGAAGAAGATTGAGGAGGCGATGGACGGAAGTGAGACA
  CCTCAGCTCTTCACTGTGTTGCCAGAGAAGAGAACAGCCACTGTTGGAGGGGCCATGATG
  GGATCAACCCACATTTATGACATGTCCACGGTTATGAGCCGGAAGGGCCCGGCTCCTGAG
  CTGCAAGGTGTGGAAGTGGCGCTGGCGCCTGAAGAGTTGGAGCTGGATCCTATGGCCATG
  ACCCAGAAGTATGAGGAGCATGTGCGGGAGCAGCAGGCTCAAGTAGAGAAGGAGGACTTC
  AGTGACATGGTGGCTGAGCACGCTGCCAAACAGAAGCAAAAAAAACGGAAAGCTCAGCCC
  CAGGACAGCCGTGGGGGCAGCAAGAAATATAAGGAGTTCAAGTTT
  
• Restriction Sites: Please inquire
• ACCN: NM_006842
• ORF Size: 2688 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006842.2, NP_006833.2
• RefSeq Size: 2902
• RefSeq ORF: 2688
• Locus ID: 10992
• Domains: SAP, PSP, DUF382
• Protein Pathways: Spliceosome
• Gene Summary: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]