EDEM3 (NM_025191) Human Untagged Clone

CAT#: SC318399

EDEM3 (untagged)-Human ER degradation enhancer, mannosidase alpha-like 3 (EDEM3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EDEM3
• Synonyms: C1orf22
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_025191, the custom clone sequence may differ by one or more nucleotides
  ATGAGCGAAGCCGGCGGCCGGGGCTGTGGGTCCCCGGTTCCCCAGCGAGCGCGATGGAGA
  CTAGTGGCGGCGACGGCCGCGTTCTGCCTGGTGTCGGCCACCTCCGTGTGGACGGCGGGG
  GCCGAGCCCATGAGTAGGGAGGAGAAACAGAAGCTTGGGAATCAAGTACTGGAAATGTTT
  GATCATGCTTATGGTAACTATATGGAACATGCTTACCCTGCTGATGAACTCATGCCTTTA
  ACCTGTAGAGGTCGAGTTAGAGGCCAAGAGCCAAGTCGCGGTGACGTTGATGATGCCTTG
  GGAAAATTTTCTCTGACACTGATTGATTCTTTGGACACTCTTGTGGTTTTAAATAAAACT
  AAAGAATTTGAAGATGCAGTGAGAAAAGTTTTAAGAGATGTTAATTTAGATAACGATGTA
  GTCGTATCAGTCTTTGAAACAAACATCAGAGTTCTTGGGGGTCTTTTGGGTGGGCACTCC
  CTGGCAATCATGCTGAAAGAAAAAGGTGAATATATGCAGTGGTACAATGATGAACTTCTC
  CAAATGGCAAAGCAGTTAGGTTACAAACTTTTACCGGCTTTCAACACTACCAGTGGCCTT
  CCTTATCCAAGAATTAATTTAAAGTTTGGCATCAGAAAACCAGAAGCTCGGACAGGAACT
  GAGACAGATACCTGTACAGCTTGTGCAGGTACCTTGATCCTTGAATTTGCTGCTTTAAGT
  CGATTCACAGGAGCAACAATATTTGAGGAATATGCCAGAAAAGCTCTTGATTTTCTCTGG
  GAAAAAAGACAGCGAAGTAGTAATTTAGTGGGCGTGACTATAAATATTCATACTGGAGAT
  TGGGTACGAAAAGATAGTGGAGTTGGAGCAGGGATTGATTCATATTATGAATATCTGTTG
  AAAGCCTATGTCTTGCTTGGAGATGACAGTTTTCTGGAAAGATTTAACACACACTATGAT
  GCCATAATGAGGTATATTAGCCAGCCACCTCTTCTACTTGATGTGCATATCCACAAACCA
  ATGCTGAATGCTCGGACTTGGATGGATGCTTTGCTTGCCTTCTTCCCAGGCTTGCAGGTG
  TTAAAGGGGGATATTAGACCTGCTATTGAAACTCATGAAATGTTATATCAGGTGATTAAA
  AAACACAATTTTCTACCAGAGGCATTTACCACAGATTTCAGAGTACACTGGGCTCAACAT
  CCTTTAAGGCCAGAATTTGCAGAAAGTACCTACTTCTTATATAAAGCTACAGGAGATCCT
  TACTACCTTGAAGTAGGGAAGACACTTATTGAAAATTTAAATAAATATGCTAGAGTGCCT
  TGCGGATTTGCTGCCATGAAGGATGTTCGTACTGGAAGTCATGAGGACAGAATGGATTCT
  TTCTTCTTGGCTGAAATGTTTAAATATCTTTACCTGTTATTTGCTGATAAAGAAGACATT
  ATTTTTGACATAGAAGATTACATCTTTACAACAGAAGCTCATCTGTTACCTCTTTGGCTC
  TCTACTACAAATCAAAGCATCTCTAAAAAGAACACAACCTCGGAATATACAGAACTGGAT
  GACAGTAACTTCGATTGGACTTGTCCAAATACTCAGATCCTCTTTCCTAATGACCCATTG
  TATGCTCAAAGTATTCGTGAGCCCTTGAAAAATGTGGTGGATAAGAGCTGTCCTAGAGGC
  ATCATCAGAGTAGAGGAGAGTTTCAGGAGTGGAGCTAAACCCCCTCTGAGAGCCAGAGAT
  TTCATGGCCACTAACCCTGAGCATTTAGAAATCCTGAAGAAGATGGGGGTGAGTTTGATT
  CACCTCAAAGATGGGAGAGTCCAGTTGGTCCAACATGCAATCCAAGCTGCTAGTTCAATC
  GACGCTGAAGATGGGTTGAGGTTCATGCAGGAGATGATTGAATTGTCAAGTCAGCAACAA
  AAAGAACAGCAGCTGCCTCCACGAGCTGTACAAATTGTTTCCCACCCATTTTTTGGCAGG
  GTAGTATTGACTGCTGGACCAGCTCAGTTTGGGCTGGATCTGTCTAAACATAAAGAGACA
  AGAGGATTTGTTGCAAGCAGTAAACCATCCAATGGTTGTTCAGAGCTTACTAACCCAGAG
  GCAGTGATGGGAAAAATCGCACTGATACAAAGAGGACAGTGCATGTTTGCAGAAAAGGCA
  CGCAACATCCAGAATGCTGGAGCCATTGGTGGCATTGTTATTGATGACAATGAGGGGAGC
  AGCAGTGATACTGCCCCTCTGTTCCAGATGGCAGGTGATGGAAAGGATACAGATGACATC
  AAGATCCCCATGCTGTTCTTATTCAGCAAAGAAGGAAGTATCATACTGGATGCCATCCGG
  GAATATGAGGAGGTAGAAGTGCTCCTCTCTGATAAAGCAAAAGATCGAGATCCTGAAATG
  GAAAATGAAGAACAACCATCCTCTGAAAATGATTCTCAGAATCAGAGTGGTGAACAGATT
  TCATCAAGTTCTCAGGAGGTTGATTTGGTTGATCAAGAGTCTTCTGAGGAAAATTCTCTA
  AATTCTCACCCAGAATCATTATCTCTAGCAGATATGGACAATGCTGCAAGCATTTCCCCT
  TCTGAACAGACTTCTAATCCCACAGAAAACCATGAGACTACAAATCTTAATGGTGAATGT
  ACAGATTTAGATAACCAGCTTCAAGAACAATCAGAAACTGAGGAAGATTCCAATCCTAAT
  GTTAGCTGGGGTAAAAAGGTCCAGCCTATAGACTCCATATTAGCAGACTGGAATGAAGAT
  ATAGAAGCATTTGAAATGATGGAGAAGGATGAGCTA
  
• Restriction Sites: Please inquire
• ACCN: NM_025191
• ORF Size: 2799 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_025191.3, NP_079467.3
• RefSeq Size: 6670
• RefSeq ORF: 2799
• Locus ID: 80267
• Domains: Glyco_hydro_47, PA
• Gene Summary: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.