EDEM3 (NM_025191) Human Tagged ORF Clone

CAT#: RC222885L3

Lenti-ORF clone of EDEM3 (Myc-DDK-tagged)-Human ER degradation enhancer, mannosidase alpha-like 3 (EDEM3)

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: EDEM3
• Synonyms: C1orf22
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222885).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_025191
• ORF Size: 2796 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_025191.3, NP_079467.3
• RefSeq Size: 6670
• RefSeq ORF: 2799
• Locus ID: 80267
• Domains: Glyco_hydro_47, PA
• MW: 105.1 kDa
• Gene Summary: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]). [supplied by OMIM, Mar 2008]