PTPRU (NM_133177) Human Untagged Clone

CAT#: SC318621

PTPRU (untagged)-Human protein tyrosine phosphatase, receptor type, U (PTPRU), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRU
• Synonyms: FMI; hPTP-J; PCP-2; PTP; PTP-J; PTP-PI; PTP-RO; PTPPSI; PTPRO; PTPU2; R-PTP-PSI; R-PTP-U
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_133177, the custom clone sequence may differ by one or more nucleotides
  ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACC
  GAGACTCCGGCAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAG
  TACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAGTGCGAATCCACCCTGGCACC
  CGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCC
  CCAGGCCAGCGAGCCCATGTCATCTTCCAGAGCCTGAGCGAGAATGATACCCACTGTGTG
  CAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCTGGGCGTCTAC
  GTGCGCGTTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGC
  CGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAATGAATATCAGGTG
  CTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTG
  CTTCTCAGCTACCCCTGCGCAAAGGCCCCACACTTCTCCCGCCTGGGCGACGTGGAGGTC
  AACGCGGGCCAGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAA
  CGCTTCCTCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGGCACATC
  AGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCGCGCCGAGCAGGAC
  CTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTC
  ATCGTCAAGGAGCCCCCAACTCCCATCGCGCCCCCACAGCTGCTGCGTGCTGGCCCCACC
  TACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAG
  GAGATTGAGTACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAG
  ACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATGAGATCAGCGTGCTGCTCACG
  CGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGC
  GCAGAGCCCATGAGGGCCCCCAAAGGCCTGGCTTTTGCTGAGATCCAGGCCCGTCAGCTG
  ACCCTGCAGTGGGAACCACTGGGCTACAACGTGACGCGTTGCCACACCTATACTGTGTCG
  CTGTGCTATCACTACACCCTGGGCAGCAGCCACAACCAGACCATCCGAGAGTGTGTGAAG
  ACAGAGCAAGGTGTCAGCCGCTACACCATCAAGAACCTGCTGCCCTATCGGAACGTTCAC
  GTGAGGCTTGTCCTCACTAACCCTGAGGGGCGCAAAGAGGGCAAGGAGGTCACTTTCCAG
  ACGGATGAGGATGTGCCCAGTGGGATTGCAGCCGAGTCCCTGACCTTCACTCCACTGGAG
  GACATGATCTTCCTCAAGTGGGAGGAGCCCCAGGAGCCCAATGGTCTCATCACCCAGTAT
  GAGATCAGCTACCAGAGCATCGAGTCATCAGACCCGGCAGTGAACGTGCCAGGCCCACGA
  CGTACCATCTCCAAGCTCCGCAATGAGACCTACCATGTCTTCTCCAACCTGCACCCAGGC
  ACCACCTACCTGTTCTCCGTGCGGGCCCGCACAGGCAAAGGCTTCGGCCAGGCGGCACTC
  ACTGAGATAACCACTAACATCTCTGCTCCCAGCTTTGATTATGCCGACATGCCGTCACCC
  CTGGGCGAGTCTGAGAACACCATCACCGTGCTGCTGAGGCCGGCACAGGGCCGCGGTGCG
  CCCATCAGTGTGTACCAGGTGATTGTGGAGGAGGAGCGGGCGCGGAGGCTGCGGCGGGAG
  CCAGGTGGACAGGACTGCTTCCCAGTGCCATTGACCTTCGAGGCGGCGCTGGCCCGAGGC
  CTGGTGCACTACTTCGGGGCCGAACTGGCGGCCAGCAGTCTACCTGAGGCCATGCCCTTT
  ACCGTGGGTGACAACCAGACCTACCGAGGCTTCTGGAACCCACCACTTGAGCCTAGGAAG
  GCCTATCTCATCTACTTCCAGGCAGCAAGCCACCTGAAGGGGGAGACCCGGCTGAATTGC
  ATCCGCATTGCCAGGAAAGCTGCCTGCAAGGAAAGCAAGCGGCCCCTGGAGGTGTCCCAG
  AGATCGGAGGAGATGGGGCTTATCCTGGGCATCTGTGCAGGGGGGCTTGCTGTCCTCATC
  CTTCTCCTGGGTGCCATCATTGTCATCATCCGCAAAGGGAAGCCGGTGAACATGACCAAG
  GCCACCGTCAACTACCGCCAGGAGAAGACACACATGATGAGCGCCGTGGACCGCAGCTTC
  ACAGACCAGAGCACCCTGCAGGAGGACGAGCGGCTGGGCCTGTCCTTCATGGACACCCAT
  GGCTACAGCACCCGGGGAGACCAGCGCAGCGGTGGGGTCACTGAGGCCAGCAGCCTCCTG
  GGGGGCTCCCCGAGGCGTCCCTGTGGCCGGAAGGGCTCCCCATACCACACGGGGCAGCTG
  CACCCTGCGGTGCGTGTCGCAGACCTTCTGCAGCACATCAACCAGATGAAGACGGCCGAG
  GGTTACGGCTTCAAGCAGGAGTATGAGAGCTTCTTTGAAGGCTGGGACGCCACAAAGAAG
  AAAGACAAGGTCAAGGGCAGCCGGCAGGAGCCAATGCCTGCCTATGATCGGCACCGAGTG
  AAACTGCACCCGATGCTGGGAGACCCCAATGCCGACTACATTAATGCCAACTACATAGAT
  ATTCGGATAAACCGAGAAGGTTACCACAGGTCAAACCACTTCATAGCCACTCAAGGGCCG
  AAGCCTGAGATGGTCTATGACTTCTGGCGTATGGTGTGGCAGGAGCACTGTTCCAGCATC
  GTCATGATCACCAAGCTGGTCGAGGTGGGCAGGGTGAAATGCTCACGGTACTGGCCGGAG
  GACTCAGACACCTACGGGGACATCAAGATTATGCTGGTGAAGACAGAGACCCTGGCTGAG
  TATGTCGTGCGCACTTTTGCCCTGGAGCGGAGAGGCTACTCTGCCCGGCACGAGGTCCGC
  CAGTTCCACTTCACAGCGTGGCCAGAGCATGGCGTCCCCTACCATGCCACGGGGCTGCTG
  GCTTTCATCCGGCGCGTGAAGGCCTCCACCCCACCTGATGCCGGGCCCATTGTCATCCAC
  TGCAGCGCGGGCACCGGCCGCACAGGTTGCTATATCGTCCTGGATGTGATGCTGGACATG
  GCAGAGTGTGAGGGCGTCGTGGACATTTACAACTGTGTGAAGACTCTCTGCTCCCGGCGT
  GTCAACATGATCCAGACTGAGGAGCAGTACATCTTCATTCATGATGCAATCCTGGAGGCC
  TGCCTGTGTGGGGAGACCACCATCCCTGTCAGTGAGTTCAAGGCCACCTACAAGGAGATG
  ATCCGCATTGATCCTCAGAGTAATTCCTCCCAGCTGCGGGAAGAGTTCCAGACGCTGAAC
  TCGGTCACCCCGCCGCTGGACGTGGAGGAGTGCAGCATCGCCCTGTTGCCCCGGAACCGC
  GACAAGAACCGCAGCATGGACGTCCTGCCGCCCGACCGCTGCCTGCCCTTCCTCATCTCC
  ACTGATGGGGACTCCAACAACTACATTAATGCAGCCCTGACTGACAGCTACACACGGAGT
  GCGGCCTTCATCGTGACCCTGCACCCGCTGCAGAGCACCACGCCCGACTTCTGGCGGCTG
  GTCTACGATTACGGGTGCACCTCCATCGTCATGCTCAACCAGCTGAACCAGTCCAACTCC
  GCCTGGCCCTGCCTGCAGTACTGGCCAGAGCCAGGCCGGCAGCAATATGGCCTCATGGAG
  GTGGAGTTTATGTCGGGCACAGCTGATGAAGACTTAGTGGCTCGAGTCTTCCGGGTGCAG
  AACATCTCTCGGTTGCAGGAGGGGCACCTGCTGGTGCGGCACTTCCAGTTCCTGCGCTGG
  TCTGCATACCGGGACACACCTGACTCCAAGAAGGCCTTCTTGCACCTGCTGGCTGAGGTG
  GACAAGTGGCAGGCCGAGAGTGGGGATGGGCGCACCATCGTGCACTGCCTAAACGGGGGA
  GGACGCAGCGGCACCTTCTGCGCCTGCGCCACGGTCCTGGAGATGATCCGCTGCCACAAC
  TTGGTGGACGTTTTCTTTGCTGCCAAAACCCTCCGGAACTACAAACCCAACATGGTGGAG
  ACCATGGATCAGTACCACTTTTGCTACGATGTGGCCCTGGAGTACTTGGAGGGGCTGGAG
  TCAAGA
  
• Restriction Sites: Please inquire
• ACCN: NM_133177
• ORF Size: 4329 bp
• Insert Size: 5614
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_133177.2, NP_573438.2
• RefSeq Size: 5614
• RefSeq ORF: 4329
• Locus ID: 10076
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon, contains an alternate in-frame exon, and uses an alternate, in-frame splice site compared to variant 3. The resulting isoform (2) has the same N- and C-termini but is 6 aa shorter than isoform 3.