DLG5 (NM_004747) Human Untagged Clone

CAT#: SC318695

DLG5 (untagged)-Human discs, large homolog 5 (Drosophila) (DLG5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DLG5
• Synonyms: LP-DLG; P-DLG5; PDLG
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004747 edited
  CGGCGCCCTAGGGCTGCTGCCGAGGTGCTCGCCTGCCCGCCCGCCGGCCTCGGGGGGCCC
  GGGAGGCGTCCGGCGGGGCGGGGCGGCGCGGCCCGCCACCATGGAGCCCCAGCGCCGGGA
  GCTGCTCGCCCAGTGTCAGCAGAGCCTGGCCCAGGCCATGACGGAGGTGGAAGCCGTGCT
  CGGGCTGCTCGAGGCCGCGGGAGCGCTCAGTCCCGGCGAGCGGCGGCAGCTGGACGAGGA
  GGCGGGAGGCGCCAAGGCGGAGCTGCTGCTCAAGCTGCTCTTGGCCAAGGAGCGGGACCA
  CTTCCAGGACCTGCGGGCGGCGCTGGAGAAGACGCAGCCTCACCTGCTGCCCATTCTCTA
  CCTGAACGGCGTCGTCGGGCCGCCGCAGCCCGCCGAAGGCGCGGGTTCTACCTACAGCGT
  CCTGTCCACCATGCCCTCAGACTCAGAAAGCAGCAGCTCCCTCAGCAGTGTGGGCACTAC
  CGGGAAGGCGCCGTCCCCACCACCCCTCCTCACTGACCGGCAAGTGAATGAGAAGGTGGA
  GAACCTCTCCATTCAGCTGCGGCTGATGACCCGGGAGAGAAACGAGCTCCGCAAGCGCCT
  GGCCTTTGCTACGCATGGCACGGCCTTTGACAAGAGGCCCTACCACAGGCTGAATCCTGA
  CTATGAGAGGCTGAAGATCCAGTGCGTGCGAGCCATGTCGGACCTGCAGAGCCTGCAGAA
  CCAGCACACCAACGCCTTGAAGAGGTGTGAGGAGGTGGCCAAGGAGACTGACTTCTACCA
  CACACTCCACAGCCGGCTCCTGAGTGACCAGACTCGGCTGAAGGATGACGTGGACATGCT
  GAGGCGGGAGAATGGGCAGCTGCTGCGGGAGCGAAACCTGCTGCAGCAGTCATGGGAGGA
  CATGAAGCGGCTCCACGAGGAGGACCAGAAGGAGATCGGTGACCTCCGTGCCCAGCAGCA
  GCAGGTGTTGAAGCACAACGGGTCATCCGAGATTCTCAACAAACTGTATGACACGGCCAT
  GGACAAGTTGGAGGTGGTCAAGAAGGACTATGACGCCCTTCGGAAGAGGTACAGTGAGAA
  AGTCGCCATCCACAATGCAGACCTGAGCCGCCTGGAGCAGCTGGGGGAGGAGAACCAGCG
  GTTGCTGAAGCAGACAGAGATGCTGACCCAGCAGAGGGACACGGCCATCCAGCTGCAGCA
  CCAGTGCGCCCTCTCCCTGAGGAGGTTTGAGGCGATCCACCATGAGCTGAACAAGGCCAC
  GGCGCAGAACAAGGACCTGCAGTGGGAGATGGAGCTGCTGCAGTCAGAGCTGACCGAGCT
  GAGAACCACGCAGGTGAAGACAGCAAAGGAGTCGGAGAAATACAGGGAGGAGCGGGACGC
  TGTGTACAGCGAGTACAAGCTCATCATGAGTGAGCGTGACCAGGTCATCTCTGAGCTGGA
  CAAGCTGCAGACCGAAGTGGAGCTGGCCGAGTCCAAGCTCAAGAGCAGCACATCTGAGAA
  GAAGGCGGCCAATGAGGAGATGGAGGCGCTGCGGCAGATCAAAGACACGGTGACAATGGA
  TGCTGGGAGAGCCAACAAGGAGGTTGAAATCCTTCGAAAGCAGTGCAAGGCTCTGTGCCA
  GGAGCTGAAGGAAGCCCTCCAGGAGGCGGATGTGGCCAAGTGCCGGCGGGACTGGGCCTT
  CCAGGAGCGAGACAAGATTGTAGCAGAGCGTGACAGCATCCGGACACTGTGTGACAACCT
  GAGGCGGGAGCGGGACCGTGCGGTGAGCGAGCTGGCTGAGGCCCTGCGCAGCCTGGATGA
  CACCCGCAAGCAGAAGAATGATGTCAGCCGCGAGCTGAAGGAGCTCAAGGAACAGATGGA
  ATCCCAGTTGGAAAAGGAGGCCCGGTTCCGACAGCTGATGGCCCACAGCTCCCACGACTC
  GGCCATTGACACGGATTCCATGGAGTGGGAAACGGAAGTTGTAGAGTTCGAGAGGGAGAC
  GGAGGATATTGACTTGAAGGCACTGGGGTTTGATATGGCAGAAGGTGTGAATGAGCCTTG
  TTTCCCGGGGGACTGTGGCATATTTGTCACTAAAGTGGACAAAGGAAGCATTGCTGATGG
  CCGCTTAAGGGTCAATGACTGGCTGCTGAGAATCAACGATGTGGACCTCATCAACAAGGA
  CAAGAAGCAGGCCATCAAGGCGCTCCTCAATGGGGAGGGGGCCATCAACATGGTCGTGCG
  GCGGAGGAAGTCCCTGGGTGGGAAGGTGGTCACGCCGCTGCACATCAACCTCAGTGGACA
  GAAAGACAGTGGCATCAGTCTGGAGAATGGAGTGTATGCTGCCGCTGTGCTGCCTGGAAG
  CCCTGCCGCTAAAGAAGGGTCCCTTGCTGTGGGAGACAGGATCGTTGCGATCAATGGCAT
  TGCACTGGACAACAAGTCTCTGAATGAATGTGAATCTCTGCTGCGGAGCTGCCAGGACTC
  CCTGACCCTGTCCCTCCTGAAGGTATTCCCTCAGAGCTCCTCGTGGAGTGGCCAGAACAT
  TTTTGAAAATATCAAAGACTCTGATAAGATGCTGAGTTTTCGAGCCCATGGCCCGGAGGT
  CCAGGCTCATAACAAACGGAACTTGATACAGCACAATAACTCCACGCAGACAGACATCTT
  CTACACGGACAGGCTGGAAGACAGGAAGGAGCCAGGCCCCCCAGGAGGCAGCAGCTCCTT
  TCTGCATAAGCCATTCCCTGGGGGACCCTTGCAGGTCTGCCCCCAGGCCTGTCCCAGTGC
  CTCTGAGCGTAGCCTGAGCTCCTTCCGCTCAGATGCCTCTGGGGACCGTGGCTTTGGGCT
  GGTGGACGTGCGTGGCCGGCGGCCACTGCTGCCCTTTGAGACCGAGGTGGGCCCCTGTGG
  GGTTGGGGAGGCCTCCCTGGACAAGGCAGACTCTGAAGGCTCCAACAGCGGCGGGACCTG
  GCCCAAGGCCATGCTCAGCTCCACGGCAGTGCCTGAGAAGCTCTCTGTTTATAAAAAGCC
  AAAGCAAAGAAAGTCCATCTTTGACCCTAACACTTTCAAACGCCCCCAGACACCCCCCAA
  AATAGACTACCTGCTTCCAGGTCCTGGGCCTGCTCACTCTCCCCAGCCCTCCAAGAGGGC
  GGGGCCTCTGACACCCCCAAAACCTCCCAGAAGGAGCGACTCCATTAAGTTCCAGCACAG
  GCTGGAGACTAGCTCCGAGTCAGAAGCCACTCTGGTGGGCAGCTCCCCATCCACTAGTCC
  CCCGAGCGCCCTGCCCCCTGACGTGGACCCCGGGGAGCCCATGCACGCATCACCCCCTCG
  CAAGGCCAGGGTCCGCATTGCTTCCAGCTACTACCCTGAAGGAGATGGGGACTCCTCCCA
  CCTGCCGGCCAAGAAATCCTGTGATGAGGACCTCACCTCCCAGAAGGTGGATGAGCTGGG
  GCAGAAGCGTCGCCGGCCAAAATCTGCTCCCAGTTTTCGGCCGAAGCTTGCTCCAGTAGT
  GATTCCTGCTCAGTTCCTGGAGGAACAGAAGTGTGTCCCGGCCAGTGGAGAACTCTCCCC
  GGAGCTCCAGGAGTGGGCACCTTACTCGCCTGGGCATTCCAGCCGGCACAGCAACCCCCC
  GCTATACCCTAGCAGGCCGTCTGTGGGCACTGTTCCCCGGAGTTTGACCCCCAGCACCAC
  TGTGAGCTCCATCCTGCGGAACCCCATCTACACTGTGCGCAGTCACAGGGTCGGCCCCTG
  CAGCTCTCCACCTGCGGCCCGAGATGCTGGCCCCCAGGGTTTGCATCCCAGTGTCCAGCA
  CCAGGGACGCCTGAGCCTGGACCTGAGCCACAGGACCTGCAGCGACTACTCCGAGATGAG
  AGCCACCCATGGGTCCAACTCACTGCCCTCCAGCGCCCGCCTGGGTTCTTCGAGTAACTT
  GCAGTTCAAGGCGGAACGCATTAAAATCCCATCAACACCAAGATATCCGCGGAGTGTCGT
  GGGCTCTGAGAGAGGTTCAGTGTCACATTCTGAATGCAGCACTCCTCCACAGTCACCCCT
  GAACATCGACACCCTGTCCTCTTGTAGCCAGTCCCAGACCTCAGCCTCCACATTGCCCAG
  AATCGCTGTCAACCCCGCGTCCCTCGGGGAGCGGAGAAAGGACAGGCCTTATGTGGAGGA
  GCCACGCCACGTGAAGGTGCAGAAGGGCTCAGAGCCGCTGGGCATCTCCATCGTGAGTGG
  AGAGAAGGGCGGCATCTACGTCTCCAAGGTGACCGTGGGGAGCATCGCTCACCAGGCTGG
  CCTCGAGTATGGGGATCAGTTACTGGAGTTCAACGGCATAAACCTGCGGAGCGCCACGGA
  GCAGCAGGCGCGGCTCATCATCGGGCAGCAGTGTGATACCATCACCATCCTGGCCCAGTA
  CAACCCCCACGTGCACCAGCTCAGCAGCCACTCCCGGTCCAGCTCACACCTGGACCCTGC
  CGGTACCCACTCCACTCTCCAGGGCAGTGGCACCACCACCCCGGAGCATCCATCTGTCAT
  CGACCCACTGATGGAGCAGGACGAGGGGCCTAGCACCCCCCCAGCCAAGCAGAGCAGCTC
  CAGGATTGCGGGAGATGCCAACAAGAAGACCCTGGAGCCACGCGTTGTCTTCATCAAAAA
  GTCCCAGCTGGAGCTTGGGGTGCACTTGTGTGGTGGGAACCTGCATGGGGTGTTTGTGGC
  CGAGGTGGAGGATGACAGTCCTGCCAAGGGTCCTGACGGCCTCGTGCCAGGGGACCTCAT
  CCTGGAGTATGGCAGCCTGGACGTGCGGAACAAGACAGTGGAGGAAGTCTATGTGGAGAT
  GCTGAAGCCCAGGGATGGCGTCCGCCTGAAGGTGCAGTACCGCCCTGAGGAGTTCACGAA
  GGCCAAGGGCCTGCCTGGTGACAGCTTCTACATCAGGGCCCTGTACGACCGGCTGGCAGA
  TGTGGAGCAAGAGTTGAGCTTTAAGAAGGATGACATCCTCTACGTGGATGACACCTTACC
  CCAGGGCACGTTCGGGTCCTGGATGGCTTGGCAGCTGGACGAGAATGCCCAGAAGATCCA
  GCGCGGGCAGATTCCCAGCAAATATGTGATGGACCAAGAATTCTCCAGGAGGCTCAGCAT
  GTCTGAAGTCAAAGATGACAATAGCGCCACAAAGACGCTGTCAGCGGCTGCACGCCGGTC
  CTTTTTTCGGAGGAAACACAAGCACAAACGCAGCGGGTCCAAGGACGGGAAAGACCTGCT
  CGCCTTGGATGCCTTTTCCAGTGACTCCATTCCACTCTTTGAAGATTCGGTGAGCCTGGC
  CTATCAGCGGGTCCAGAAGGTGGACTGCACCGCTCTGAGGCCTGTCCTGATTCTGGGGCC
  TTTGCTGGACGTGGTGAAGGAGATGCTGGTGAATGAGGCTCCTGGCAAGTTCTGCAGATG
  TCCCCTTGAGGTGATGAAGGCCTCCCAGCAGGCCATTGAGCGGGGTGTCAAAGATTGCCT
  GTTTGTCGACTATAAGCGGAGAAGCGGCCATTTCGATGTGACCACTGTGGCGTCAATAAA
  GGAGATCACAGAAAAGAACCGACACTGCCTCCTGGACATTGCTCCGCACGCTATTGAGCG
  GCTCCACCACATGCACATCTACCCTATTGTCATCTTCATCCACTACAAGAGCGCCAAGCA
  CATCAAGGAGCAGAGAGACCCCATCTACCTGAGGGACAAGGTGACTCAGAGGCATTCCAA
  AGAGCAGTTTGAGGCGGCGCAGAAGCTTGAGCAGGAGTACAGCAGGTACTTCACAGGGGT
  CATCCAGGGAGGAGCCCTGTCAAGCATTTGCACTCAGATCTTGGCAATGGTCAATCAAGA
  ACAAAATAAAGTCCTGTGGATTCCAGCCTGCCCGCTCTAGGAGAATGCTGTGCTGTGGAT
  GACTGCAGCTGGCCGCCTGAGGGGACGCCAGACTCAGCTCTTTTCTAGCGACTGAAAGTA
  GAAGTCTGTCCGTCTATGAACATGCAGGGGAAGGATCCGGAACCAGGACCCAGAAGCACC
  TCCTTTGTAGACAGAGGGCCACGGCTGCGTGCGATCCAGGCCCAGGCCCACACACTCTGC
  CCGTGTCACACGTGTGCTTTAACACAAAACAGATAACACTAAAGACGGGTTCAGCACCCA
  CCTTTCTTTAGCCAGCTGATCAGAGATGCTGCAAAGAGAACCTTTCGGATCACTCGTTTA
  CAAGCCTTTTCTAAGTATTTGGTGGTTTATGTTTACTTGAACGGCTCCATGTTGCCGGTG
  CCCAGCCCCTGTCCCCTCTGTCAACCCCCTGTCGCTTTGGTGTTGGTTTCGTTCCCGTCT
  TCAGCAAAACGACCTTGGAACCTCAATGGGGGCTGCTTTGCTTTGGGAGGTTCTTGTTGG
  TGGGACCAGAGCTTTGACAAACCTCCTGCTCCTTGGTGGCACCTCTCCTGGAAGGACGTC
  ACAACTCCAGGTGCTCAGACTGCCTGTGGCAGCAGAACCAGTGCCTTTGGCATTTTCCTC
  CCACAATGGGGAAGGTGACTTTGGCATTCTTACAAACTCGTCTCTCGGCCTTTCTCTCCT
  GCCTTCCACAGCCTCTCGTTTCTCCTCCATCTGTGCTTATTACTTGAGGACTGTGTCTGC
  TCCGTGAGAGCTGCGTGGGCAGGGCTGCAGTGGGGTCCAGGTGGTGTTCAGCTGTGCTGA
  TGCCTGCCATTGGGTCCTCCTTAGGCTCTGTAAGTCGTGACAGCCTTCATCAGTGCAATG
  TTTGCAGGGTAATTCTTAAACTTTTTAGAGGGTGGCAGGTACATCAGTTCTTTTTGATAT
  GAAAACATTCATGTTTCAGACATTGAATTGAGAGCTTTTAGGGGAAGCATAATGGTTATT
  GTCACTATCAACAGTCTAAAAAGAAAAACTGAGGTCTTTTTAATCTTGATTACAGCACTC
  ACGGCATGCACCCTACTCAGTGTGGGTGTCTTCGTTTGGGGGCTTTTTTTTTTTTTGCAC
  TTCTGAGGCTAGATATGTCTGGCTGAAGATTTGATGTGGTTCCTCCTTAAGCTATGCGTC
  CTGTTAATAATAGGTACTGTACTGGGCTCTGTGTAAGTGTCGTTGGGGTAGGACCTATAT
  TTTAATACTGTTCCTAACATTTCATTTTACTAGCGAGAAATCTTTGATTTCATTTTATTC
  TTTGTAATTCTAGA
  
• Restriction Sites: Please inquire
• ACCN: NM_004747
• ORF Size: 5760 bp
• Insert Size: 7200
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_004747.3.

Reference Data

• RefSeq: NM_004747.3, NP_004738.3
• RefSeq Size: 7493
• RefSeq ORF: 5760
• Locus ID: 9231
• Domains: SH3, PDZ, Guanylate_kin, GuKc
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]