Complement Component 6 (C6) (NM_001115131) Human Untagged Clone

CAT#: SC319008

C6 (untagged)-Human complement component 6 (C6), transcript variant 2


  "NM_001115131" in other vectors (4)

Reconstitution Protocol

USD 760.00

3 Weeks*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol C6
Synonyms complement component 6; OTTHUMP00000120010
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001115131, the custom clone sequence may differ by one or more nucleotides


ATGGCCAGACGCTCTGTCTTGTACTTCATCCTGCTGAATGCTCTGATCAACAAGGGCCAAGCCTGCTTCT
GTGATCACTATGCATGGACTCAGTGGACCAGCTGCTCAAAAACTTGCAATTCTGGAACCCAGAGCAGACA
CAGACAAATAGTAGTAGATAAGTACTACCAGGAAAACTTTTGTGAACAGATTTGCAGCAAGCAGGAGACT
AGAGAATGTAACTGGCAAAGATGCCCCATCAACTGCCTCCTGGGAGATTTTGGACCATGGTCAGACTGTG
ACCCTTGTATTGAAAAACAGTCTAAAGTTAGATCTGTCTTGCGTCCCAGTCAGTTTGGGGGACAGCCATG
CACTGCGCCTCTGGTAGCCTTTCAACCATGCATTCCATCTAAGCTCTGCAAAATTGAAGAGGCTGACTGC
AAGAATAAATTTCGCTGTGACAGTGGCCGCTGCATTGCCAGAAAGTTAGAATGCAATGGAGAAAATGACT
GTGGAGACAATTCAGATGAAAGGGACTGTGGGAGGACAAAGGCAGTATGCACACGGAAGTATAATCCCAT
CCCTAGTGTACAGTTGATGGGCAATGGGTTTCATTTTCTGGCAGGAGAGCCCAGAGGAGAAGTCCTTGAT
AACTCTTTCACTGGAGGAATATGTAAAACTGTCAAAAGCAGTAGGACAAGTAATCCATACCGTGTTCCGG
CCAATCTGGAAAATGTCGGCTTTGAGGTACAAACTGCAGAAGATGACTTGAAAACAGATTTCTACAAGGA
TTTAACTTCTCTTGGACACAATGAAAATCAACAAGGCTCATTCTCAAGTCAGGGGGGGAGCTCTTTCAGT
GTACCAATTTTTTATTCCTCAAAGAGAAGTGAAAATATCAACCATAATTCTGCCTTCAAACAAGCCATTC
AAGCCTCTCACAAAAAGGATTCTAGTTTTATTAGGATCCATAAAGTGATGAAAGTCTTAAACTTCACAAC
GAAAGCTAAAGATCTGCACCTTTCTGATGTCTTTTTGAAAGCACTTAACCATCTGCCTCTAGAATACAAC
TCTGCTTTGTACAGCCGAATATTCGATGACTTTGGGACTCATTACTTCACCTCTGGCTCCCTGGGAGGCG
TGTATGACCTTCTCTATCAGTTTAGCAGTGAGGAACTAAAGAACTCAGGTTTAACCGAGGAAGAAGCCAA
ACACTGTGTCAGGATTGAAACAAAGAAACGCGTTTTATTTGCTAAGAAAACAAAAGTGGAACATAGGTGC
ACCACCAACAAGCTGTCAGAGAAACATGAAGGTTCATTTATACAGGGAGCAGAGAAATCCATATCCCTGA
TTCGAGGTGGAAGGAGTGAATATGGAGCAGCTTTGGCATGGGAGAAAGGGAGCTCTGGTCTGGAGGAGAA
GACATTTTCTGAGTGGTTAGAATCAGTGAAGGAAAATCCTGCTGTGATTGACTTTGAGCTTGCCCCCATC
GTGGACTTGGTAAGAAACATCCCCTGTGCAGTGACAAAACGGAACAACCTCAGGAAAGCTTTGCAAGAGT
ATGCAGCCAAGTTCGATCCTTGCCAGTGTGCTCCATGCCCTAATAATGGCCGACCCACCCTCTCAGGGAC
TGAATGTCTGTGTGTGTGTCAGAGTGGCACCTATGGTGAGAACTGTGAGAAACAGTCTCCAGATTATAAA
TCCAATGCAGTAGACGGACAGTGGGGTTGTTGGTCTTCCTGGAGTACCTGTGATGCTACTTATAAGAGAT
CGAGAACCCGAGAATGCAATAATCCTGCCCCCCAACGAGGAGGGAAACGCTGTGAGGGGGAGAAGCGACA
AGAGGAAGACTGCACATTTTCAATCATGGAAAACAATGGACAACCATGTATCAATGATGACGAAGAAATG
AAAGAGGTCGATCTTCCTGAGATAGAAGCAGATTCCGGGTGTCCTCAGCCAGTTCCTCCAGAAAATGGAT
TTATCCGGAATGAAAAGCAACTATACTTGGTTGGAGAAGATGTTGAAATTTCATGCCTTACTGGCTTTGA
AACTGTTGGATACCAGTACTTCAGATGCTTACCAGACGGGACCTGGAGACAAGGGGATGTGGAATGCCAA
CGGACGGAGTGCATCAAGCCAGTTGTGCAGGAAGTCCTGACAATTACACCATTTCAGAGATTGTATAGAA
TTGGTGAATCCATTGAGCTAACTTGCCCCAAAGGCTTTGTTGTTGCTGGGCCATCAAGGTACACATGCCA
GGGGAATTCCTGGACACCACCCATTTCAAACTCTCTCACCTGTGAAAAAGATACTCTAACAAAATTAAAA
GGCCATTGTCAGCTGGGACAGAAACAATCAGGATCTGAATGCATTTGTATGTCTCCAGAAGAAGACTGTA
GCCATCATTCAGAAGATCTCTGTGTGTTTGACACAGACTCCAACGATTACTTTACTTCACCCGCTTGTAA
GTTTTTGGCTGAGAAATGTTTAAATAATCAGCAACTCCATTTTCTACATATTGGTTCCTGCCAAGACGGC
CGCCAGTTAGAATGGGGTCTTGAAAGGACAAGACTTTCATCCAACAGCACAAAGAAAGAATCCTGTGGCT
ATGACACCTGCTATGACTGGGAAAAATGTTCAGCCTCCACTTCCAAATGTGTCTGCCTATTGCCCCCACA
GTGCTTCAAGGGTGGAAACCAACTCTACTGTGTCAAAATGGGATCATCAACAAGTGAGAAAACATTGAAC
ATCTGTGAAGTGGGAACTATAAGATGTGCAAACAGGAAGATGGAAATACTGCATCCTGGAAAGTGTTTGG
CCTAG


Restriction Sites SgfI-RsrII     
ACCN NM_001115131
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001115131.2, NP_001108603.2
RefSeq Size 3749 bp
RefSeq ORF 2805 bp
Locus ID 729
Cytogenetics 5p13.1
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
Gene Summary 'This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]'
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.