ARHGEF14 (MCF2L) (NM_001112732) Human Untagged Clone

CAT#: SC319026

MCF2L (untagged)-Human MCF.2 cell line derived transforming sequence-like (MCF2L), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCF2L
• Synonyms: ARHGEF14; DBS; OST
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001112732, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGTTTTGGCTGAGGACTGAAGAGATGGCCTTGGAAGAAATGGTGCAGAGATTAAATGCGGTTTCCA
  AGCACACGGATGAAATCATGCACCAGGACATCGTCCCGCTCTGTGCTGCCGACATCCAGGACCAGCTAAA
  GAAGCGCTTTGCTTACCTGTCCGGTGGGCGGGGGCAGGACGGAAGCCCGGTTATCACCTTCCCTGACTAC
  CCGGCCTTCAGCGAGATTCCGGACAAGGAGTTCCAGAATGTCATGACCTACCTCACCAGCATCCCCAGCC
  TGCAGGACGCTGGCATCGGATTCATCCTGGTGATAGACCGGCGACGGGACAAATGGACCTCCGTGAAGGC
  GTCCGTCCTGCGCATCGCAGCATCTTTCCCGGCAAACCTGCAGCTCGTCCTCGTGCTTCGCCCGACGGGT
  TTTTTCCAAAGGACTCTCTCCGACATCGCTTTCAAATTCAATAGAGATGACTTTAAGATGAAGGTGCCGG
  TCATAATGCTGAGCTCCGTACCAGACTTACACGGTTACATCGATAAGTCGCAGCTGACCGAGGACCTGGG
  TGGGACCCTGGACTACTGCCACTCCCGGTGGCTGTGCCAGCGCACGGCCATCGAAAGTTTCGCCCTCATG
  GTGAAGCAGACGGCTCAGATGCTGCAGTCCTTCGGGACCGAGCTGGCTGAAACAGAGCTGCCCAATGACG
  TCCAGTCGACAAGCTCAGTGCTGTGTGCGCACACAGAGAAGAAGGACAAGGCGAAGGAGGATTTGAGGCT
  GGCACTGAAAGAGGGGCACAGTGTCCTGGAGAGCCTCAGGGAGCTGCAGGCTGAGGGCTCAGAGCCCAGT
  GTGAACCAGGACCAGCTTGACAACCAGGCCACCGTGCAGAGGCTCCTGGCCCAGCTGAACGAAACCGAGG
  CTGCCTTCGATGAGTTCTGGGCAAAGCATCAGCAGAAACTGGAGCAGTGTCTGCAGCTCCGGCACTTTGA
  GCAGGGCTTCCGGGAGGTCAAAGCCATCTTGGACGCAGCGTCCCAGAAGATAGCAACCTTCACAGACATC
  GGCAACAGCCTGGCGCATGTGGAGCACCTGCTGAGGGACCTGGCCAGCTTCGAGGAGAAATCAGGCGTGG
  CCGTGGAGAGGGCCCGGGCCCTGTCTCTGGACGGCGAGCAGCTCATTGGGAACAAGCACTACGCGGTAGA
  CTCCATCCGCCCAAAGTGCCAGGAGCTCCGGCACCTCTGTGACCAGTTCTCTGCGGAGATCGCAAGGAGG
  AGGGGGCTGCTCAGCAAGTCCCTGGAGCTGCACCGCCGCCTGGAGACGTCCATGAAGTGGTGTGATGAAG
  GGATTTACCTGCTGGCCTCACAACCTGTGGACAAGTGCCAGTCCCAGGACGGCGCGGAGGCTGCCCTCCA
  GGAAATCGAGAAGTTTTTGGAGACCGGTGCGGAAAATAAGATCCAGGAGCTCAACGCGATTTACAAGGAA
  TACGAATCCATCCTCAACCAAGATCTCATGGAGCACGTGCGAAAGGTCTTCCAGAAGCAGGCAAGCATGG
  AGGAGGTGTTCCACCGCAGGCAGGCCAGCCTGAAGAAGCTGGCGGCCAGGCAGACGCGGCCCGTGCAGCC
  GGTGGCCCCCAGACCCGAGGCACTGGCAAAGTCGCCCTGCCCCTCCCCAGGCATTCGGCGAGGCTCTGAG
  AACTCCAGCTCCGAGGGCGGTGCGCTCCGGAGAGGGCCCTACCGGAGGGCCAAGAGTGAGATGAGTGAGA
  GCCGGCAGGGCCGCGGCTCAGCGGGGGAGGAGGAGGAAAGCCTGGCCATCCTGCGCAGGCACGTGATGAG
  CGAGCTCCTGGACACAGAACGGGCCTACGTGGAGGAGCTGCTGTGCGTCCTGGAGGGCTACGCCGCGGAG
  ATGGATAACCCACTGATGGCTCACCTCCTGTCAACAGGCCTTCACAACAAGAAGGATGTTTTGTTTGGAA
  ACATGGAGGAAATCTATCACTTCCACAACAGGATATTCCTCAGGGAGCTGGAAAACTACACTGACTGCCC
  AGAACTGGTTGGAAGATGCTTTCTGGAGAGGATGGAAGATTTCCAGATCTATGAGAAGTACTGTCAGAAC
  AAGCCCCGCTCTGAGAGCCTGTGGAGACAGTGCTCCGACTGCCCGTTTTTCCAGGAATGCCAGAGAAAGC
  TGGACCACAAGCTGAGCCTGGACTCCTACCTGCTGAAGCCAGTGCAGAGGATCACCAAGTACCAGCTGCT
  GCTCAAGGAAATGCTGAAATACAGCAGGAACTGCGAGGGGGCTGAGGACCTGCAGGAGGCGCTGAGCTCC
  ATCCTGGGCATCCTGAAGGCCGTGAACGACTCCATGCACCTCATCGCTATCACCGGCTATGACGGGAATC
  TCGGCGACCTGGGCAAGCTGCTGATGCAGGGCTCGTTCAGCGTCTGGACCGACCACAAGAGGGGCCACAC
  CAAGGTGAAGGAGCTGGCCAGGTTCAAGCCCATGCAGCGGCACCTGTTCCTGCACGAGAAGGCAGTGCTC
  TTCTGCAAGAAGAGGGAGGAGAATGGGGAGGGGTATGAGAAAGCTCCCTCCTACAGCTACAAGCAGTCCT
  TAAACATGGCTGCCGTTGGCATTACGGAGAACGTGAAGGGAGATGCTAAGAAGTTCGAGATCTGGTACAA
  CGCGCGCGAGGAGGTCTACATCGTCCAGGCGCCAACTCCTGAGATTAAAGCCGCGTGGGTGAATGAAATT
  CGGAAAGTGCTGACCAGCCAGCTGCAGGCTTGTAGAGAAGCCAGCCAGCACCGGGCGCTGGAGCAGTCAC
  AGAGCCTGCCCCTGCCGGCCCCGACCAGCACCAGTCCCTCAAGAGGAAACTCAAGGAACATCAAGAAGCT
  GGAAGAAAGGAAAACAGACCCCCTAAGCCTGGAGGGATACGTCAGCTCAGCGCCACTGACAAAGCCCCCC
  GAAAAGGGCAAAGGTTGGAGCAAAACGTCCCACTCACTGGAGGCACCTGAGGACGACGGGGGCTGGTCAA
  GTGCAGAGGAGCAGATTAACTCGTCCGACGCAGAGGAGGACGGCGGGTTGGGCCCCAAGAAGCTGGTTCC
  AGGTAAATACACGGTCGTGGCGGACCACGAGAAGGGAGGCCCCGATGCGCTGCGCGTGAGGAGCGGGGAC
  GTGGTGGAGCTGGTGCAGGAGGGCGACGAGGGCCTCTGGTACGTCAGGGACCCGACCACTGGCAAGGAGG
  GCTGGGTGCCGGCCAGCAGCCTGTCCGTCCGGCTCGGCCCGTCCGGCTCGGCCCAGTGCCTGAGCAGCTC
  AGAGTCGAGCCCGGGGTCGGCCGTGCTGAGCAACTCGTCCAGCTGCAGCGAGGGCGGCCAGGCCCCCTTC
  TCCGACCTGCAGGGGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001112732
• ORF Size: 3378 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001112732.2, NP_001106203.2
• RefSeq Size: 6424
• RefSeq ORF: 3378
• Locus ID: 23263
• Gene Summary: This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  Transcript Variant: This variant (1) encodes isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The coding region has been updated to represent an alternative splicing pattern that is more supported by the available transcript data.