NFAT5 (NM_001113178) Human Untagged Clone

CAT#: SC319033

NFAT5 (untagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFAT5
• Synonyms: NF-AT5; NFATL1; NFATZ; OREBP; TONEBP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001113178, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCTCGGACTTCATCTCATTGCTCAGCGCGGACCTAGACCTGGAATCGCCCAAGTCCCTCTACTCGC
  GAGATTCTCTGAAGTTACACCCATCACAGAATTTTCATAGAGCTGGACTATTGGAAGAATCTGTCTATGA
  TCTTCTCCCAAAGGAGTTACAGTTACCTCCATCTAGAGAAACATCTGTAGCATCAATGAGTCAGACAAGC
  GGTGGTGAGGCAGGCTCGCCTCCTCCAGCTGTTGTTGCTGCTGATGCTTCTTCAGCTCCCTCCTCTTCCT
  CCATGGGCGGTGCTTGCAGCTCCTTTACCACCTCTTCCAGCCCTACCATTTATTCTACCTCAGTCACCGA
  CAGCAAGGCTATGCAAGTGGAGAGCTGCTCCTCAGCCGTGGGGGTAAGTAACAGAGGGGTAAGTGAAAAG
  CAGTTAACCAGTAACACAGTTCAGCAGCATCCATCAACACCGAAGAGGCACACAGTCTTGTACATCTCAC
  CACCACCTGAGGACTTGCTGGATAACAGTCGGATGTCCTGCCAGGATGAGGGGTGTGGATTGGAATCTGA
  GCAGAGCTGCAGTATGTGGATGGAGGATTCCCCCTCCAACTTCAGTAACATGAGCACCAGTTCCTACAAT
  GATAACACTGAGGTACCTCGTAAATCACGAAAACGAAATCCAAAGCAGAGGCCGGGGGTCAAACGACGAG
  ATTGTGAAGAATCTAATATGGATATATTTGATGCCGACAGTGCCAAAGCACCTCACTATGTGCTTTCTCA
  GCTTACCACGGACAACAAAGGCAACTCAAAAGCGGGAAATGGAACATTGGAAAACCAAAAAGGAACTGGA
  GTAAAGAAGAGCCCTATGTTGTGTGGACAATATCCTGTTAAAAGTGAGGGAAAGGAGCTGAAGATAGTTG
  TACAACCTGAGACACAGCACCGAGCTCGGTACCTGACTGAGGGCAGCCGTGGCTCAGTGAAAGATAGAAC
  ACAGCAAGGCTTTCCTACAGTAAAGCTGGAAGGCCATAATGAACCTGTAGTGTTGCAAGTGTTTGTGGGC
  AACGACTCTGGACGAGTGAAACCACATGGATTTTATCAGGCCTGCAGAGTAACTGGACGAAATACAACTC
  CTTGCAAAGAAGTGGACATTGAAGGCACTACTGTTATAGAAGTCGGCCTTGATCCTAGCAACAACATGAC
  ACTGGCGGTGGACTGCGTAGGGATATTGAAATTGAGGAATGCTGATGTCGAAGCCAGAATAGGAATTGCT
  GGTTCCAAGAAGAAAAGCACTCGTGCCAGATTGGTTTTTCGAGTTAATATCATGAGGAAAGATGGCTCCA
  CTTTGACACTGCAAACACCCTCTTCTCCAATTTTGTGTACTCAGCCAGCAGGAGTGCCAGAAATCTTAAA
  GAAAAGCTTGCATAGCTGTTCAGTGAAAGGAGAAGAAGAAGTGTTTTTAATCGGCAAGAACTTTCTGAAA
  GGAACTAAAGTTATTTTCCAAGAAAATGTTTCTGATGAAAACTCTTGGAAGTCAGAAGCTGAAATTGATA
  TGGAACTATTTCATCAGAATCATCTTATTGTGAAGGTTCCTCCCTATCATGACCAACATATAACTTTGCC
  TGTGTCAGTGGGAATATATGTAGTGACAAATGCTGGAAGATCTCATGATGTTCAACCATTCACTTACACT
  CCAGACCCAGCAGCTGGTGCTTTGAATGTAAATGTGAAGAAGGAAATATCTAGTCCAGCAAGACCTTGCT
  CTTTTGAAGAGGCCATGAAAGCAATGAAAACTACTGGATGTAATTTAGATAAGGTAAATATTATCCCTAA
  TGCCCTGATGACTCCACTCATACCAAGCAGTATGATTAAGAGTGAAGATGTTACTCCAATGGAAGTAACA
  GCAGAAAAAAGATCTTCCACTATTTTTAAGACTACAAAGTCTGTTGGATCAACTCAGCAAACATTAGAAA
  ACATCTCAAACATAGCAGGAAATGGCTCTTTTTCATCACCATCATCTTCCCACCTACCTTCTGAAAATGA
  AAAACAGCAGCAGATTCAGCCCAAGGCATACAACCCAGAGACCCTGACAACTATTCAAACCCAGGACATC
  TCACAGCCTGGTACTTTTCCAGCAGTTTCTGCTTCTAGTCAGCTGCCCAACAGCGATGCACTATTGCAGC
  AGGCTACACAGTTTCAGACAAGAGAAACTCAGTCTAGAGAGATATTACAGTCAGATGGTACAGTGGTTAA
  TTTGTCACAACTGACTGAGGCATCACAACAACAGCAGCAGTCACCACTACAAGAACAAGCACAGACTTTA
  CAGCAGCAGATTTCATCAAATATTTTTCCATCACCAAATAGTGTGAGTCAGCTTCAGAATACTATTCAGC
  AGCTGCAAGCAGGGAGTTTCACAGGCAGTACTGCTAGTGGCAGCAGTGGAAGTGTTGACTTGGTCCAACA
  AGTTTTAGAGGCACAGCAGCAGTTATCTTCAGTTTTATTTTCTGCTCCAGATGGTAATGAGAATGTTCAA
  GAGCAGCTTAGTGCAGATATTTTTCAACAAGTCAGTCAAATTCAGAGTGGTGTAAGCCCTGGAATGTTTT
  CCTCAACAGAGCCAACAGTCCATACCAGACCAGATAATTTATTACCTGGAAGAGCTGAAAGTGTTCATCC
  ACAGTCTGAAAACACGTTATCTAATCAACAGCAGCAGCAGCAGCAGCAACAGCAAGTGATGGAATCTTCA
  GCCGCAATGGTGATGGAGATGCAACAGAGTATCTGCCAGGCAGCTGCCCAGATTCAGTCAGAGTTATTCC
  CTTCAACTGCTTCAGCAAATGGAAACCTTCAGCAATCGCCAGTTTACCAGCAGACTTCTCACATGATGAG
  TGCATTGTCTACCAATGAGGATATGCAAATGCAGTGTGAATTGTTTTCTTCTCCTCCTGCAGTTTCTGGA
  AATGAAACTTCTACAACTACCACACAGCAGGTTGCAACCCCTGGCACTACCATGTTTCAGACATCAAGTT
  CAGGAGATGGAGAAGAAACTGGAACACAAGCAAAACAGATTCAGAACAGTGTCTTTCAGACCATGGTCCA
  AATGCAACATAGTGGGGACAATCAACCTCAAGTTAACCTTTTTTCATCCACAAAAAGTATGATGAGTGTT
  CAGAATAGTGGTACCCAACAACAAGGTAATGGTTTATTCCAGCAAGGGAATGAGATGATGTCACTTCAAT
  CTGGAAATTTTTTGCAGCAGTCTTCTCATTCACAGGCCCAACTTTTTCATCCTCAAAATCCTATTGCCGA
  TGCTCAGAACCTTTCCCAGGAAACTCAAGGTTCTCTCTTTCATAGTCCAAATCCTATTGTCCACAGTCAG
  ACTTCTACAACCTCCTCTGAACAAATGCAGCCTCCAATGTTTCACTCTCAAAGTACCATTGCTGTGTTAC
  AGGGCTCTTCAGTTCCTCAAGACCAGCAGTCAACCAACATATTTCTTTCCCAGAGTCCCATGAATAATCT
  TCAGACTAACACAGTAGCCCAAGAAGCATTTTTTGCAGCACCGAACTCAATTTCTCCACTTCAGTCAACA
  TCAAACAGTGAACAACAAGCTGCTTTCCAACAGCAAGCTCCAATATCACACATCCAGACTCCTATGCTTT
  CCCAAGAACAGGCACAACCCCCGCAGCAGGGTTTATTTCAGCCTCAGGTGGCCCTGGGCTCCCTTCCACC
  TAATCCAATGCCTCAAAGCCAACAAGGAACCATGTTCCAGTCACAGCACTCAATAGTTGCCATGCAGAGT
  AACTCTCCATCCCAGGAACAGCAGCAGCAGCAGCAACAGCAGCAGCAACAGCAGCAGCAACAACAACAGA
  GCATTTTATTCAGTAATCAGAATACCATGGCTACAATGGCGTCTCCAAAGCAACCACCACCAAACATGAT
  ATTCAACCCAAATCAAAATCCAATGGCTAATCAGGAGCAACAGAACCAGTCAATTTTTCACCAACAAAGT
  AACATGGCCCCAATGAATCAAGAGCAACAGCCCATGCAATTTCAGAGTCAGTCCACAGTTTCCTCACTTC
  AGAACCCAGGTCCTACCCAGTCGGAATCATCACAGACCCCCTTGTTCCATAGCTCTCCTCAGATTCAGTT
  GGTACAAGGGTCACCTAGTTCTCAAGAGCAGCAAGTAACTCTCTTCTTATCTCCAGCATCCATGTCTGCC
  TTGCAGACCAGTATAAATCAACAAGATATGCAACAGTCTCCTCTTTATTCCCCTCAGAACAACATGCCTG
  GAATTCAAGGAGCCACATCTTCGCCTCAACCACAGGCTACTTTATTTCACAACACAGCAGGAGGCACAAT
  GAACCAACTGCAGAATTCTCCTGGCTCATCTCAGCAGACATCAGGAATGTTCTTATTTGGCATTCAAAAT
  AACTGTAGTCAGCTTTTAACCTCTGGACCAGCTACATTGCCTGATCAGTTGATGGCCATAAGTCAGCCAG
  GCCAACCACAAAACGAGGGCCAGCCACCTGTGACAACACTTCTTTCTCAGCAAATGCCAGAGAATTCTCC
  ACTGGCATCCTCTATAAACACCAACCAGAACATCGAAAAGATTGATTTGCTTGTTTCATTGCAAAACCAA
  GGGAACAACTTGACTGGCTCCTTTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001113178
• ORF Size: 4647 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001113178.2, NP_001106649.1
• RefSeq Size: 13304
• RefSeq ORF: 4647
• Locus ID: 10725
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (6) lacks an exon in the 5' region and uses an alternate in-frame splice site in the central coding region, compared to variant 1. These differences result in an isoform (d) with a longer N-terminus and lacking an internal aa, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.