Neurexin II alpha (NRXN2) (NM_015080) Human Untagged Clone

CAT#: SC319037

NRXN2 (untagged)-Human neurexin 2 (NRXN2), transcript variant alpha-1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NRXN2
• Synonyms: FLJ40892; KIAA0921
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015080, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTGGCGCTGGCGG
  CGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGCTACGCGCGCTGGGCGGGCGC
  GGCGAGCAGCGGCGAGCTCAGCTTCAGCCTGCGCACCAACGCCACGCGCGCGCTGCTGCTCTACCTGGAC
  GACGGCGGCGACTGCGACTTCCTGGAGCTGCTGCTGGTGGACGGCCGCCTGCGGCTGCGCTTCACGCTTT
  CGTGCGCCGAGCCGGCCACGCTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCT
  GACCCGCGACGCGCGCCGCACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAG
  CGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGCCCGACGTGCGCCTCTCGGCGC
  TTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCCAACCTGAAGCTGGGCGAGCG
  GCCCCCCGCGCTGCTGGGCAGCCAGGGCCTGCGCGGCGCCACCGCCGACCCGCTGTGCGCGCCCGCGCGC
  AACCCCTGCGCCAACGGCGGCCTCTGCACCGTGCTGGCCCCCGGCGAGGTGGGCTGCGACTGCAGCCACA
  CGGGCTTCGGCGGCAAGTTCTGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAAA
  CAGCGAAGTAGGGTCCTTACTGTTCTCCGAGGGGGGGGCCGGGAGAGGAGGAGCCGGCGATGTGCACCAG
  CCAACAAAAGGCAAGGAGGAGTTTGTGGCGACCTTCAAAGGCAATGAGTTCTTCTGCTACGACCTGTCAC
  ACAACCCCATCCAGAGCAGCACTGATGAGATCACACTGGCCTTCCGCACCCTGCAACGCAACGGCCTGAT
  GCTGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCCCTCAAGTCTGGGGCTGTCTGGCTGGTCATC
  AACCTAGGCTCAGGTGCCTTCGAGGCCCTTGTGGAACCCGTCAATGGCAAGTTCAACGACAACGCCTGGC
  ACGACGTCCGGGTCACCCGAAACCTGCGCCAGCACGCAGGGATTGGACACGCTATGGTAAACAAACTGCA
  TTATCTGGTGACCATCTCGGTGGACGGGATCCTGACCACCACAGGCTACACGCAGGAGGATTACACCATG
  CTGGGCTCTGATGACTTCTTCTACATTGGGGGCAGCCCCAACACAGCTGACCTGCCGGGCTCGCCCGTCA
  GCAACAACTTCATGGGCTGCCTCAAGGACGTGGTCTATAAGAACAATGACTTCAAATTGGAACTATCCCG
  CCTGGCAAAGGAAGGGGACCCCAAGATGAAGCTGCAGGGGGACTTGTCATTCCGCTGTGAGGATGTGGCT
  GCCCTGGACCCTGTGACCTTTGAGAGTCCCGAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCTAAGCGCA
  CTGGCTCCATCTCCCTAGACTTCCGCACCACCGAGCCCAATGGGCTGCTGCTCTTCAGCCAGGGCCGGCG
  GGCTGGGGGTGGAGCTGGCAGCCACAGCTCTGCTCAGCGGGCCGACTACTTTGCCATGGAGCTATTGGAC
  GGCCACCTCTATCTTCTGCTGGACATGGGATCTGGGGGCATCAAGCTGCGGGCATCCAGCCGCAAGGTCA
  ATGATGGCGAGTGGTGTCACGTGGACTTCCAGAGGGATGGGCGAAAAGGCTCCATCTCAGTGAATAGTCG
  CAGCACGCCGTTCTTGGCCACTGGAGACAGCGAGATTCTGGACCTGGAGAGTGAGCTGTACCTGGGCGGT
  CTCCCTGAGGGGGGCCGGGTGGACCTGCCCCTGCCCCCAGAGGTGTGGACAGCAGCACTCCGGGCAGGCT
  ACGTGGGCTGTGTGCGGGACCTCTTCATAGATGGGCGTAGCCGAGACCTCCGGGGCCTGGCTGAGGCTCA
  GGGGGCTGTGGGCGTTGCCCCCTTTTGCTCCCGGGAGACGCTGAAGCAGTGTGCATCTGCCCCCTGTCGC
  AATGGGGGCGTCTGTCGAGAAGGCTGGAACCGCTTCATCTGTGACTGCATCGGGACCGGCTTTCTTGGGC
  GGGTCTGTGAGAGAGAGGCCACGGTCCTGAGCTACGATGGCTCCATGTACATGAAGATCATGCTGCCTAA
  CGCCATGCACACGGAGGCAGAGGATGTGTCCCTGCGTTTCATGTCCCAGCGGGCCTACGGACTCATGATG
  GCCACCACTTCCAGGGAGTCTGCCGACACCCTACGCCTGGAGCTGGATGGGGGGCAGATGAAGCTCACTG
  TCAACCTCGACTGCCTGCGCGTCGGCTGCGCACCCAGTAAAGGCCCCGAAACGCTGTTTGCGGGGCACAA
  GCTCAATGACAATGAGTGGCACACGGTGAGGGTGGTCCGGCGTGGCAAGAGCCTGCAGCTGTCTGTGGAC
  AACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGTTCCACAACATTGAGACGGGCA
  TCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGGCATCTGAGTGGGCTCGTGTT
  CAATGGCCAGCCCTACATGGACCAGTGCAAGGATGGTGACATCACCTACTGTGAGCTCAATGCTCGCTTT
  GGCCTGCGTGCCATCGTGGCCGATCCCGTCACCTTCAAGAGTCGCAGCAGCTACCTGGCACTCGCCACGC
  TCCAAGCCTATGCTTCCATGCACCTCTTCTTCCAGTTCAAGACCACGGCCCCTGATGGGCTTCTTCTGTT
  CAACTCGGGCAACGGCAATGACTTCATTGTCATCGAGCTGGTCAAGGGGTACATCCACTACGTGTTTGAC
  CTGGGGAATGGCCCGTCCTTGATGAAGGGGAACTCAGACAAACCAGTCAATGACAACCAGTGGCACAACG
  TGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCCCGCACTGTCACGCAGCACTC
  CAATGGCGCCCGAAACCTCGATCTCAAAGGGGAGTTGTACATTGGCGGTCTGAGCAAGAATATGTTCAGC
  AACCTGCCCAAGCTGGTGGCCTCCCGGGATGGCTTTCAGGGCTGCCTGGCCTCAGTGGACCTCAACGGAC
  GTCTCCCAGACCTCATCGCCGACGCCCTGCACCGCATTGGGCAGGTGGAGAGGGGCTGTGATGGCCCCAG
  CACCACCTGCACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGCAGTGGGATGGCTTCACCTGC
  GACTGCACCATGACTTCCTATGGAGGCCCTGTCTGCAATGATCCCGGGACCACATACATCTTTGGGAAGG
  GGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACGAGGATGGATCGCCTGGCCGT
  GGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGGGTGGACAGCGCCTCCGGCCTTGGAGACTAC
  CTGCAGCTGCACATCGACCAGGGCACCGTGGGGGTGATCTTTAACGTGGGCACGGACGACATTACCATCG
  ACGAGCCCAACGCCATAGTAAGCGACGGCAAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGC
  CACCCTGCAGGTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGAAACTTTGATAACGAGCGCCTG
  GCGATTGCTAGACAGAGAATCCCCTACCGGCTTGGTCGAGTAGTAGATGAGTGGCTGCTCGACAAAGGCC
  GCCAGCTGACCATCTTCAACAGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCA
  GGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTGGCCGCCGAGAGCGACCCCAAT
  GTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGG
  CCACCACCCTGCTGGCTGACATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCACCAC
  GCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCACCCAGAACACAGATGACCTGCTGGTGGCCTCT
  GCTGAGTGTCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTGC
  CCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGTGCCCCCGCCCCC
  TACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCAAGACACGCTGCCCCCGCCCGCCGCGCGCCGC
  CCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCATCGAGGCCTCGG
  GCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTT
  TCCCCTGGTCACGGACCGCACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACA
  GATGGGGCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCTGCCGGCGGGCA
  AAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTC
  CTTTGAGCCGCGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCTGCCC
  ACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCGGGCGCAGTGGAGGTGATCCGGGAGTCCAGCA
  GCACCACGGGCATGGTGGTGGGCATTGTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCAT
  GTATAAGTACCGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCG
  GCCCAGAGCAATGGGGCGGTGGTGAAAGAGAAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAAGA
  AGAACAAAGACAAGGAGTATTATGTCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015080
• ORF Size: 5139 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015080.3, NP_055895.1
• RefSeq Size: 6639
• RefSeq ORF: 5139
• Locus ID: 9379
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992). [provided by RefSeq, Jun 2010]
  Transcript Variant: This variant (alpha-1) encodes the longest isoform (alpha-1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.