HSPBP1 (NM_012267) Human Untagged Clone

CAT#: SC319052

HSPBP1 (untagged)-Human HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 (HSPBP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HSPBP1
• Synonyms: FES1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012267.3 GCAGAGTCAGGTGCGGACGACTTTGTCTGTAGGAGCAGCGGCGGCTTGAGGACCCGGGGA
  GACCCTCAAGAATCGACCCATCAGGACGCCAGAGCTGCTTCAGCGGTGACCACCTTCTCC
  CTCTAACACATTCTTCCCTTCTTCACAAACGGCCCATGTCAGACGAAGGCTCAAGGGGGA
  GCCGCCTGCCCCTGGCGCTGCCCCCGGCCTCCCAGGGTTGCTCTTCAGGGGGCGGCGGCG
  GCGGCTCCTCGGCTGGGGGCTCGGGCAATTCCCGGCCCCCACGCAACCTCCAAGGCTTGC
  TGCAGATGGCCATCACCGCGGGCTCTGAAGAGCCAGACCCTCCTCCAGAACCGATGAGTG
  AGGAGAGGCGTCAGTGGCTGCAGGAGGCCATGTCGGCTGCCTTCCGAGGCCAGCGGGAGG
  AGGTGGAGCAGATGAAGAGCTGCCTCCGAGTGCTGTCACAGCCCATGCCCCCCACTGCTG
  GGGAGGCCGAGCAGGCGGCCGACCAGCAAGAGCGAGAGGGGGCCCTGGAGCTGCTGGCCG
  ACCTGTGTGAGAACATGGACAATGCCGCAGACTTCTGCCAGCTGTCTGGCATGCACCTGC
  TGGTGGGCCGGTACCTGGAGGCGGGGGCTGCGGGACTGCGGTGGCGGGCGGCACAGCTCA
  TCGGCACGTGCAGTCAGAACGTGGCAGCCATCCAGGAGCAGGTGCTGGGCCTGGGTGCCC
  TGCGTAAGCTGCTGCGGCTGCTGGACCGCGACGCCTGCGACACGGTGCGCGTCAAGGCCC
  TCTTCGCCATCTCCTGTCTGGTCCGAGAGCAGGAGGCTGGGCTGCTGCAGTTCCTCCGCC
  TGGACGGCTTCTCTGTGTTGATGAGGGCCATGCAGCAGCAGGTGCAGAAGCTCAAGGTCA
  AATCAGCATTCCTGCTGCAGAACCTGCTGGTGGGCCACCCTGAACACAAAGGGACCCTGT
  GCTCCATGGGGATGGTCCAGCAGCTGGTGGCCCTGGTGCGGACAGAGCACAGCCCCTTCC
  ACGAGCACGTGCTTGGAGCCCTGTGCAGCCTGGTGACAGACTTTCCGCAGGGTGTGCGCG
  AGTGTCGGGAGCCGGAACTGGGCCTGGAGGAGCTCCTCCGCCACCGCTGTCAGCTGCTGC
  AGCAGCATGAGGAGTACCAGGAGGAGCTGGAGTTCTGTGAAAAGCTGCTACAGACCTGTT
  TCTCCAGCCCAGCGGACGACAGCATGGATCGGTGAAACCAGGTGGCTTCTTGCCCCCTTC
  TCCGTGGGAACCCCAGGCCTCTTGCCTCCCTCCCCACCTACAAGGCCCTCTCCCAAGGGA
  TCGCAGGGCCTAGGTGCCTGGACCCAGGGTGTGCCAGCCCGTCTCTGTGCAGTCCCTGGA
  AGGGGCGCTGAGAAAGGCACCAGCTCCTTGGACCCCACCTCCCATGCTCTCACTCTCATC
  CCCGTTCTCTTGTCCACACAGCTCTTCCAATAAAGGTGTTTCTCTTCAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012267.3 unedited
  GGTACCTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCAGAGTCAG
  GTGCGGACGACTTTGTCTGTAGGAGCAGCGGCGGCTTGAGGACCCGGGGAGACCCTCAAG
  AATCGACCCATCAGGACGCCAGAGCTGCTTCAGCGGTGACCACCTTCTCCCTCTAACACA
  TTCTTCCCTTCTTCACAAACGGCCCATGTCAGACGAAGGCTCAAGGGGGAGCCGCCTGCC
  CCTGGCGCTGCCCCCGGCCTCCCAGGGTTGCTCTTCAGGGGGCGGCGGCGGCGGCTCCTC
  GGCTGGGGGCTCGGGCAATTCCCGGCCCCCACGCAACCTCCAAGGCTTGCTGCAGATGGC
  CATCACCGCGGGCTCTGAAGAGCCAGACCCTCCTCCAGAACCGATGAGTGAGGAGAGGCG
  TCAGTGGCTGCAGGAGGCCATGTCGGCTGCCTTCCGAGGCCAGCGGGAGGAGGTGGAGCA
  GATGAAGAGCTGCCTCCGAGTGCTGTCACAGCCCATGCCCCCCACTGCTGGGGAGGCCGA
  GCAGGCGGCCGACCAGCAAGAGCGAGAGGGGGCCCTGGAGCTGCTGGCCGACCTGTGTGA
  GAACATGGACAATGCCGCAGACTTCTGCCAGCTGTCTGGCATGCACCTGCTGGTGGGCCG
  GTACCTGGAGGCGGGGGCTGCGGGACTGCGGTGGCGGGCGGCACAGCTCATCGGCACGTG
  CAGTCAGAACGTGGCAGCCATTCCAGGAGCAGTGCTGGGCCCTGGGTGCCCTGCGTAAGC
  TGCTGCGCTGCTGAACCGCGACGCCTTGCGACACCGGTGGCGCGTCAAGGCCCTTCTTCG
  CCATTCTCCTGTCTGGTTCCGAAAGCAGGAGCTTGGCCTGCATGCAGTTCTCCGCCCTGA
  CGCTCTCTGTGTGTGATTGAGGCCATGCAGCAGCAGGTGGCAGAGCTCTAAAGTTCAAAT
  ACACCAATTCTGGTGCTGTGCAGAA
• Restriction Sites: Please inquire
• ACCN: NM_012267
• ORF Size: 1080 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012267.3, NP_036399.3
• RefSeq Size: 1559
• RefSeq ORF: 1080
• Locus ID: 23640
• Gene Summary: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 3. Variants 1 and 2 encode the same isoform (2), which has a shorter N-terminus, compared to isoform 1.