TIPRL (NM_001031800) Human Untagged Clone

CAT#: SC319268

TIPRL (untagged)-Human TIP41, TOR signaling pathway regulator-like (S. cerevisiae) (TIPRL), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TIPRL
• Synonyms: TIP; TIP41; TIPRL1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001031800.1 CCTCTGCGGGTCCTGCCTCAGCCATGATGATCCACGGCTTCCAGAGCAGCCACCGGGATT
  TCTGCTTCGGGCCCTGGAAGCTGACGGCGTCCAAGACCCACATCATGAAGTCGGCGGATG
  TGGAGAAATTAGCCGATGAATTACATATGCCATCTCTCCCTGAAATGATGTTTGGAGACA
  ACGTTTTAAGAATCCAGCATGGGTCTGGCTTTGGAATTGAGTTCAATGCTACAGATGCGT
  TAAGATGTGTAAACAACTACCAAGGAATGCTTAAAGTGGCCTGTGCTGAAGAGTGGCAAG
  AAAGCAGGACGGAGGGTGAACACTCCAAAGAGGTTATTAAACCATATGATTGGACCTATA
  CAACAGATTATAAGGGAACCTTACTTGGAGAATCTCTTAAGTTAAAGGTTGTACCTACAA
  CAGATCATATAGATACAGAAAAATTGAAAGCCAGAGAACAGATTAAGTTTTTTGAAGAAG
  TTCTCCTTTTTGAGGATGAACTTCATGATCATGGAGTTTCAAGCCTGAGTGTGAAGATTC
  CTGGTGGCGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAGCGTGAAC
  CCGGGAGGCGGAGCTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCCTCCAGCCT
  GGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAATAAAATAAAATAAAAGAAGTAG
  AAAACACAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001031800.1 unedited
  GGCACTTGTATACGACTCCTATAGGGCGGCCGGGTAATTCGGCACGAGGCCTCTGCGGGT
  CCTGCCTCAGCCATGATGATCCACGGCTTCCAGAGCAGCCACCGGGATTTCTGCTTCGGG
  CCCTGGAAGCTGACGGCGTCCAAGACCCACATCATGAAGTCGGCGGATGTGGAGAAATTA
  GCCGATGAATTACATATGCCATCTCTCCCTGAAATGATGTTTGGAGACAACGTTTTAAGA
  ATCCAGCATGGGTCTGGCTTTGGAATTGAGTTCAATGCTACAGATGCGTTAAGATGTGTA
  AACAACTACCAAGGAATGCTTAAAGTGGCCTGTGCTGAAGAGTGGCAAGAAAGCAGGACG
  GAGGGTGAACACTCCAAAGAGGTTATTAAACCATATGATTGGACCTATACAACAGATTAT
  AAGGGAACCTTACTTGGAGAATCTCTTAAGTTAAAGGTTGTACCTACAACAGATCATATA
  GATACAGAAAAATTGAAAGCCAGAGAACAGATTAAGTTTTTTGAAGAAGTTCTCCTTTTT
  GAGGATGAACTTCATGATCATGGAGTTTCAAGCCTGAGTGTGAAGATTCCTGGTGGCGGG
  CACCTGTAGTCCCAGTACTCCCGGGAGGCTGAGGCAGAGAAGCGTGAACCCGGGAGGCGG
  AGCTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCCTCAGCCTGGGCGACGAGCA
  AGACTCGTCTCAGAAAAAAAGATAGAATAAGATAAGAGTACAAACCCAAGAGAGAAGAAA
  GCTCGAGTTAACTGGCGGCCCGGTCATACTGTTCCTGACGATCCGGTGGCATCACTGAAC
  CGTACGATGGCCTCCTGGTCATGGA
• Restriction Sites: Please inquire
• ACCN: NM_001031800
• ORF Size: 537 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001031800.1, NP_001026970.1
• RefSeq Size: 854
• RefSeq ORF: 537
• Locus ID: 261726
• Gene Summary: TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]). [supplied by OMIM, Nov 2010]
  Transcript Variant: This variant (2) lacks several exons, and uses an alternate 3'-terminal exon, compared to variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.