CBX8 (NM_020649) Human Untagged Clone

CAT#: SC319326

CBX8 (untagged)-Human chromobox homolog 8 (CBX8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CBX8
• Synonyms: PC3; RC1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020649.1 ATGGTCTGTCGTGCGCTGGCTGCTGCTTTTCTGCTCCTGGAAGCGGCCAAGGGGGGAAGC
  GGCGAGTCAACATGGAGCTTTCAGCGGTGGGGGAGCGGGTGTTCGCGGCCGAAGCCCTCC
  TGAAGCGGCGCATACGGAAAGGACGCATGGAATACCTCGTGAAATGGAAGGGATGGTCGC
  AGAAGTACAGCACATGGGAACCGGAGGAAAACATCCTGGATGCTCGCTTGCTCGCAGCCT
  TTGAGGAAAGGGAAAGAGAGATGGAGCTCTATGGCCCCAAAAAGCGTGGACCCAAGCCCA
  AAACCTTCCTCCTCAAAGCGCAGGCCAAGGCAAAGGCCAAAACTTACGAGTTTCGAAGTG
  ACTCAGCCAGGGGCATCCGGATCCCCTACCCTGGCCGCTCGCCCCAGGACCTGGCCTCCA
  CTTCCCGGGCCCGGGAGGGCCTTCGAAACATGGGTTTGTCCCCGCCAGCGAGCAGCACCA
  GCACCAGCAGCACCTGCCGCGCAGAGGCCCCTCGGGACCGGGACCGAGACCGGGATAGGG
  ACCGGGAGCGGGATCGAGAAAGGGAGAGGGAGCGAGAGAGGGAGCGGGAACGTGAGAGGG
  AACGAGAGCGGGGTACCAGCAGAGTGGATGACAAGCCCAGCTCACCGGGGGACAGCTCGA
  AGAAGCGAGGCCCCAAGCCCCGGAAGGAGCTCCCGGACCCCTCACAGAGGCCCTTAGGCG
  AACCCAGCGCCGGCCTCGGAGAGTACCTCAAGGGCAGGAAGCTGGACGACACCCCTTCCG
  GGGCAGGAAAGTTTCCAGCCGGCCACAGTGTGATCCAGCTGGCCCGAAGACAGGACTCGG
  ACCTGGTGCAGTGTGGTGTGACCAGCCCTAGCTCAGCTGAGGCCACGGGCAAACTGGCTG
  TGGACACCTTCCCGGCCAGGGTGATAAAGCACAGGGCTGCCTTCCTGGAGGCCAAAGGCC
  AGGGTGCCCTAGATCCCAATGGCACCCGGGTCCGACATGGCTCAGGCCCCCCCAGCTCTG
  GGGGGGGCCTGTACCGGGACATGGGGGCCCAGGGGGGAAGGCCCTCCCTCATCGCCAGGA
  TCCCTGTGGCCAGAATCCTGGGGGACCCGGAGGAAGAGTCCTGGAGCCCCTCCCTGACTA
  ACCTGGAGAAGGTGGTGGTCACGGACGTGACCTCAAACTTTTTGACCGTCACCATTAAGG
  AAAGTAACACGGACCAAGGCTTTTTTAAAGAGAAAAGATGAATGCTGGGTGGGTGTGTCC
  AGGAGGAGAGCAGGGGAGAGAGTGAGCGTGAGCTTGGCATAGTGATTTTTATTTCTGGGT
  GGGATGTGGCCTTTTGGCTGGTCCCGTCCCTGATGTCACCCCCACCCCACCAGCCCCTTT
  CATCCCTCCTTCCTCCCCCTCAGTTTTTGTTGGAAAGATTATCTCTAGAGTTATATTTTC
  TATTAGATGTAAATATGTTATTTAAGAAAAATATCTAAATATATATATTTCAAAAAAAAA
  AAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020649.1 unedited
  GGCCATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGATGGTCTGTCGT
  GCGCTGGCTGCTGCTTTTCTGCTCCTGGAAGCGGCCAAGGGGGGAAGCGGCGAGTCAACA
  TGGAGCTTTCAGCGGTGGGGGAGCGGGTGTTCGCGGCCGAAGCCCTCCTGAAGCGGCGCA
  TACGGAAAGGACGCATGGAATACCTCGTGAAATGGAAGGGATGGTCGCAGAAGTACAGCA
  CATGGGAACCGGAGGAAAACATCCTGGATGCTCGCTTGCTCGCAGCCTTTGAGGAAAGGG
  AAAGAGAGATGGAGCTCTATGGCCCCAAAAAGCGTGGACCCAAGCCCAAAACCTTCCTCC
  TCAAAGCGCAGGCCAAGGCAAAGGCCAAAACTTACGAGTTTCGAAGTGACTCAGCCAGGG
  GCATCCGGATCCCCTACCCTGGCCGCTCGCCCCAGGACCTGGCCTCCACTTCCCGGGCCC
  GGGAGGGCCTTCGAAACATGGGTTTGTCCCCGCCAGCGAGCAGCACCAGCACCAGCAGCA
  CCTGCCGCGCAGAGGCCCCTCGGGACCGGGACCGAGACCGGGATAGGGACCGGGAGCGGG
  ATCGAGAAAGGGAGAGGGAGCGAGAGAGGGAGCGGGAACGTGAGAGGGAACGAGAGCGGG
  GTACCAGCAGAGTGGATGACAAGCCCAGCTCACCGGGGGACAGCTCGAAGAGCGAGGCCC
  CAAGCCCCGGAAGGAGCTCCCGGACCCCTCACAGAGGCCCTTAGGCGAACCCAGCGCCGG
  CCTCGGAGGAGTACCTCAGGGCAGGAAGCTGACGACACCCCTTCCGGGGCAGGAAAGTTT
  CAGCGCCACAGTGTGATCCAGCTGGCCGGAGACTGACTCGACTGTGCATGTGGGTGTGAC
  AGTCTAGCTCAGCTGAGCCACGGCAACTGGGCTGTGGAACACCCTTGCG
• Restriction Sites: Please inquire
• ACCN: NM_020649
• ORF Size: 1170 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020649.1, NP_065700.1
• RefSeq Size: 1542
• RefSeq ORF: 1170
• Locus ID: 57332
• Domains: CHROMO
• Protein Families: Transcription Factors
• Gene Summary: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. [UniProtKB/Swiss-Prot Function]