DEDD (NM_001039711) Human Untagged Clone

CAT#: SC319347

DEDD (untagged)-Human death effector domain containing (DEDD), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DEDD
• Synonyms: CASP8IP1; DEDD1; DEFT; FLDED1; KE05
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001039711.1 CACGGCCGCGGCGGCGGCGGCGGCGGCGGCTGCTGGAGCCCGGATGCGGCGCCGTGAGGC
  AGGCCCGGGAGAGCGGCGCGGATGGATCCAACATGGCGGCGCCGAGCCTGAGCCGAGAGA
  AGAGACCTGGGAAATTAAGTTTCTTGCGGAGTACGGTGGGGATTGCAGCTGCTGAGCAGG
  GATTCTGGAAAGCATTGCGTACCTGAGCCCCCAGCATGGCGGGCCTAAAGCGGCGGGCAA
  GCCAGGTGTGGCCAGAAGAGCATGGTGAGCAGGAACATGGGCTGTACAGCCTGCACCGCA
  TGTTTGACATCGTGGGCACTCATCTGACACACAGAGATGTGCGCGTGCTTTCTTTCCTCT
  TTGTTGATGTCATTGATGACCACGAGCGTGGACTCATCCGAAATGGACGTGACTTCTTAT
  TGGCACTGGAGCGCCAGGGCCGCTGTGATGAAAGTAACTTTCGCCAGGTGCTGCAGCTGC
  TGCGCATCATCACTCGCCACGACCTGCTGCCCTACGTCACCCTCAAGAGGAGACGGGCTG
  TGTGCCCTGATCTTGTAGACAAGTATCTGGAGGAGACATCAATTCGCTATGTGACCCCCA
  GAGCCCTCAGTGATCCAGAACCAAGGCCTCCCCAGCCCTCTAAAACAGTGCCTCCCCACT
  ATCCTGTGGTGTGTTGCCCCACTTCGGGTCCTCAGATGTGTAGCAAGCGGCCAGCCCGAG
  GGAGAGCCACACTTGGGAGCCAGCGAAAACGCCGGAAGTCAGTGACACCAGATCCCAAGG
  AGAAGCAGACATGTGACATCAGACTGCGGGTTCGGGCTGAATACTGCCAGCATGAGACTG
  CTCTGCAGGGCAATGTCTTCTCTAACAAGCAGGACCCACTTGAGCGCCAGTTTGAGCGCT
  TTAACCAGGCCAACACCATCCTCAAGTCCCGGGACCTGGGCTCCATCATCTGTGACATCA
  AGTTCTCTGAGCTCACCTACCTCGATGCATTCTGGCGTGACTACATCAATGGCTCTTTAT
  TAGAGGCACTTAAAGGTGTCTTCATCACAGACTCCCTCAAGCAAGCTGTGGGCCATGAAG
  CCATCAAGCTGCTGGTAAATGTAGACGAGGAGGACTATGAGCTGGGCCGACAGAAACTCC
  TGAGGAACTTGATGCTGCAAGCATTGCCCTGACCTATTCCCTCTTCTCACTTTGGGGACT
  GTTCCCATCACCCACCTCTGGAGCTTACACTGTTCTGGGGTTTGTTCTCTACCCTTCCAA
  CCAATCACACCCCTGCCTTTTTTTTTTTTTTTTTAAAGAAAAAGACAAAAGAAAGTGGAA
  GTGGTATTCCCCACCCCTCCCTGCACCCATGTGCCTGGGCTTCCCCTTTATTTCCCTTTT
  CCATTTACCCCGTAATGTGTCTCTACAGCTACCTTACCACTGAGCCGTAAGACAAATGTA
  TAGGAAGAAGCAAAGTCTACAGCACATAGTCTTTGTAAGGGATTGATGTGAACACTTTTT
  TTTGGATGCACTAAGGAGTTATCAATACTTCTGGCTTTATGAGAGCTCTTAAATTTTGTC
  TAAAAAACCAAAGGGCTGTGAGTAAGGGAGCTATGTGGAAAGTGGGACTCTGAAGTGTAT
  TTTGAAAATTAATCGCCACCCTCTTCCAAATTATAGAATTTTTTAAAAACAAGCTGTGGC
  CCTTTCCACTCTCTCCTGGCCTCTGGTGCTGCTCCTCTCTGCCGCCTTTCCTCCATTCCA
  TGGCTTGAAACCTCTGCCTGATGTGGCTCCTTCCTTTTTCCCATTTGTCAAACCCTCTTC
  AAAGGAGGAACAGATAAGACTGGGTCAGCCTAGTCATGCCTCCCAACTGTGGTGGTATAT
  GTGTACACACATACACAGGGTGGATGGAGAAGAGGTTGCTGATTAAAATACACTCCCCCT
  ATAAAGGGGAAGGGGGAGTGTGACACTTTCTTTCCATGTTCAAGTGAAAATAAATAATGT
  ACCCTGCAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001039711.1 unedited
  GTACCTTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCACGGCCGCGG
  CGGCGGCGGCGGCGGCGGCTGCTGGAGCCCGGATGCGGCGCCGTGAGGCAGGCCCGGGAG
  AGCGGCGCGGATGGATCCAACATGGCGGCGCCGAGCCTGAGCCGAGAGAAGAGACCTGGG
  AAATTAAGTTTCTTGCGGAGTACGGTGGGGATTGCAGCTGCTGAGCAGGGATTCTGGAAA
  GCATTGCGTACCTGAGCCCCCAGCATGGCGGGCCTAAAGCGGCGGGCAAGCCAGGTGTGG
  CCAGAAGAGCATGGTGAGCAGGAACATGGGCTGTACAGCCTGCACCGCATGTTTGACATC
  GTGGGCACTCATCTGACACACAGAGATGTGCGCGTGCTTTCTTTCCTCTTTGTTGATGTC
  ATTGATGACCACGAGCGTGGACTCATCCGAAATGGACGTGACTTCTTATTGGCACTGGAG
  CGCCAGGGCCGCTGTGATGAAAGTAACTTTCGCCAGGTGCTGCAGCTGCTGCGCATCATC
  ACTCGCCACGACCTGCTGCCCTACGTCACCCTCAAGAGGAGACGGGCTGTGTGCCCTGAT
  CTTGTAGACAAGTATCTGGAGGAGACATCAATTCGCTATGTGACCCCCAGAGCCCTCAGT
  GATCCAGAACCAAAGCCTCCCCAGCCCTCTAAAACAGTGCCTCCCCACTATCCTGTGGTG
  TGTTGCCCCACTTCGGGTCCTCAGATGTGTAGCAAGCGGCCAGCCCGAGGGAGAGCCACC
  ACTTGGGAGCCAGCGAAAACGCCGAGTCAGTGACACCAGATCCCAGAGAGCAGAACATTG
  TGAACATCAGACTGCGGTTCGGGCTGAATACTGCAGCATGAGACTGCTCTGCAGCCATGT
  TCTTTCTCTAACCAGCAAGGACCCACTTGGAGGCGCCAGT
• Restriction Sites: Please inquire
• ACCN: NM_001039711
• ORF Size: 957 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001039711.1, NP_001034800.1
• RefSeq Size: 2329
• RefSeq ORF: 957
• Locus ID: 9191
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 3, and 4 all encode the same isoform (b).