Mucolipin 1 (MCOLN1) (NM_020533) Human Untagged Clone

CAT#: SC319381

MCOLN1 (untagged)-Human mucolipin 1 (MCOLN1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCOLN1
• Synonyms: MG-2; ML1; ML4; MLIV; MST080; MSTP080; TRP-ML1; TRPM-L1; TRPML1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020533.1 ATCAGCTGATGCCGGAGGGTTTGAAGCCGCGCCGCGAGGGAGCGAGGTCGCAGTGACAGC
  GGCGGGCGATCGGACCCAGGCTGCCCCGCCGTACCCGCCTGCGTCCCGCGCTCCCGCCCC
  AGCATGACAGCCCCGGCGGGTCCGCGCGGCTCAGAGACCGAGCGGCTTCTGACCCCCAAC
  CCCGGGTATGGGACCCAGGCGGGGCCTTCACCGGCCCCTCCGACACCCCCAGAAGAGGAA
  GACCTTCGCCGTCGTCTCAAATACTTTTTCATGAGTCCCTGCGACAAGTTTCGAGCCAAG
  GGCCGCAAGCCCTGCAAGCTGATGCTGCAAGTGGTCAAGATCCTGGTGGTCACGGTGCAG
  CTCATCCTGTTTGGGCTCAGTAATCAGCTGGCTGTGACATTCCGGGAAGAGAACACCATC
  GCCTTCCGACACCTCTTCCTGCTGGGCTACTCGGACGGAGCGGATGACACCTTCGCAGCC
  TACACGCGGGAGCAGCTGTACCAGGCCATCTTCCATGCTGTGGACCAGTACCTGGCGTTG
  CCTGACGTGTCACTGGGCCGGTATGCGTATGTCCGTGGTGGGGGTGACCCTTGGACCAAT
  GGCTCAGGGCTTGCTCTCTGCCAGCGGTACTACCACCGAGGCCACGTGGACCCGGCCAAC
  GACACATTTGACATTGATCCGATGGTGGTTACTGACTGCATCCAGGTGGATCCCCCCGAG
  CGGCCCCCTCCGCCCCCCAGCGACGATCTCACCCTCTTGGAAAGCAGCTCCAGTTACAAG
  AACCTCACGCTCAAATTCCACAAGCTGGTCAATGTCACCATCCACTTCCGGCTGAAGACC
  ATTAACCTCCAGAGCCTCATCAATAATGAGATCCCGGACTGCTATACCTTCAGCGTCCTG
  ATCACGTTTGACAACAAAGCACACAGTGGGCGGATCCCCATCAGCCTGGAGACCCAGGCC
  CACATCCAGGAGTGTAAGCACCCCAGTGTCTTCCAGCACGGAGACAACAGCTTCCGGCTC
  CTGTTTGACGTGGTGGTCATCCTCACCTGCTCCCTGTCCTTCCTCCTCTGCGCCCGCTCA
  CTCCTTCGAGGCTTCCTGCTGCAGAACGAGTTTGTGGGGTTCATGTGGCGGCAGCGGGGA
  CGGGTCATCAGCCTGTGGGAGCGGCTGGAATTTGTCAATGGCTGGTACATCCTGCTCGTC
  ACCAGCGATGTGCTCACCATCTCGGGCACCATCATGAAGATCGGCATCGAGGCCAAGAAC
  TTGGCGAGCTACGACGTCTGCAGCATCCTCCTGGGCACCTCGACGCTGCTGGTGTGGGTG
  GGCGTGATCCGCTACCTGACCTTCTTCCACAACTACAATATCCTCATCGCCACACTGCGG
  GTGGCCCTGCCCAGCGTCATGCGCTTCTGCTGCTGCGTGGCTGTCATCTACCTGGGCTAC
  TGCTTCTGTGGCTGGATCGTGCTGGGGCCCTATCATGTGAAGTTCCGCTCACTCTCCATG
  GTGTCTGAGTGCCTGTTCTCGCTCATCAATGGGGACGACATGTTTGTGACGTTCGCCGCC
  ATGCAGGCGCAGCAGGGCCGCAGCAGCCTGGTGTGGCTCTTCTCCCAGCTCTACCTTTAC
  TCCTTCATCAGCCTCTTCATCTACATGGTGCTCAGCCTCTTCATCGCGCTCATCACCGGC
  GCCTACGACACCATCAAGCATCCCGGCGGCGCAGGCGCAGAGGAGAGCGAGCTGCAGGCC
  TACATCGCACAGTGCCAGGACAGCCCCACCTCCGGCAAGTTCCGCCGCGGGAGCGGCTCG
  GCCTGCAGCCTTCTCTGCTGCTGCGGAAGGGACCCCTCGGAGGAGCATTCGCTGCTGGTG
  AATTGATTCGACCTGACTGCCGTTGGACCGTAGGCCCTGGACTGCAGAGACCCCCGCCCC
  CGACCCCGCTTATTTATTTGTAGGGTTTGCTTTTAAGGATCGGCTCCCTGTCGCGCCCGA
  GGAGGGCCTGGACCTTTCGTGTCGGACCCTTGGGGGCGGGGAGACTGGGTGGGGAGGGTG
  TTGAATAAAAGGGAAAATAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020533.1 unedited
  GGCTAATTTGTCATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGATCAGCTGA
  TGCCGGAGGGTTTGAAGCCGCGCCGCGAGGGAGCGAGGTCGCAGTGACAGCGGCGGGCGA
  TCGGACCCAGGCTGCCCCGCCGTACCCGCCTGCGTCCCGCGCTCCCGCCCCAGCATGACA
  GCCCCGGCGGGTCCGCGCGGCTCAGAGACCGAGCGGCTTCTGACCCCCAACCCCGGGTAT
  GGGACCCAGGCGGGGCCTTCACCGGCCCCTCCGACACCCCCAGAAGAGGAAGACCTTCGC
  CGTCGTCTCAAATACTTTTTCATGAGTCCCTGCGACAAGTTTCGAGCCAAGGGCCGCAAG
  CCCTGCAAGCTGATGCTGCAAGTGGTCAAGATCCTGGTGGTCACGGTGCAGCTCATCCTG
  TTTGGGCTCAGTAATCAGCTGGCTGTGACATTCCGGGAAGAGAACACCATCGCCTTCCGA
  CACCTCTTCCTGCTGGGCTACTCGGACGGAGCGGATGACACCTTCGCAGCCTACACGCGG
  GAGCAGCTGTACCAGGCCATCTTCCATGCTGTGGACCAGTACCTGGCGTTGCCTGACGTG
  TCACTGGGCCGGTATGCGTATGTCCGTGGTGGGGGGTGACCCTTGGACCAATGGCTCAGG
  GCTTGCTCTCTGCCAGCGGTACTACCACCGAGGCCACGTGGACCCGGCCAACGACACATT
  TGACATTGATCCGATGGTGGTTACTGACTGCATCCAGGTGGATCCCCCCGAGCGGCCCCC
  TCCGCCCCCCAGCGACGATCTCACCCTCTTGAAAGCAGCTCCAGTTACAGACCTCACGCT
  CAATTCACAGCTTGTCAATGTCACATCACTCGGCTGAGACATACCTCAAGCTCATCATAT
  GAATTCGACTGCTATACTCAGCGTCTGATCACGTTGACAACAAAGCACACATGC
• Restriction Sites: Please inquire
• ACCN: NM_020533
• ORF Size: 1743 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA

Reference Data

• RefSeq: NM_020533.1, NP_065394.1
• RefSeq Size: 2051
• RefSeq ORF: 1743
• Locus ID: 57192
• Domains: ion_trans
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Gene Summary: This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV. [provided by RefSeq, Oct 2009]