NUDT5 (NM_014142) Human Untagged Clone

CAT#: SC319410

NUDT5 (untagged)-Human nudix (nucleoside diphosphate linked moiety X)-type motif 5 (NUDT5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NUDT5
• Synonyms: hNUDT5; YSA1; YSA1H; YSAH1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014142.2 AAAAAGAGCTTTAGTCTCGAAAGAGGAATTACCGAAGTGTCGAGAGAGGAATTTTAAGAA
  GTTTACAACTCCGTCTTCGCCCTAAACGCACGCTGACCCGGAAAGTAATCTCCTGAAGCT
  AGGTCAAAGGCGGGGGTTCTACGGATGCCGGAAGGAGGGTGCGCGCCCATCCTTTTAGCA
  CCGCGAGAGGCGCCGGTGTTTCGAGCCGTGGCACCGGCATCGGCTGACACTGCTGCCTCC
  AGCTAGTTATTTCGTCCTCTTCCGTTCTTCACCCCTACACCTTGGAGGTGAACTTCTCAC
  CTGAGGGCTGTAAAGACTCGTTTGAAAATGGAGAGCCAAGAACCAACGGAATCTTCTCAG
  AATGGCAAACAGTATATCATTTCAGAGGAGTTAATTTCAGAAGGAAAATGGGTCAAGCTT
  GAAAAAACAACGTACATGGATCCTACTGGTAAAACTAGAACTTGGGAATCAGTGAAACGT
  ACAACCAGGAAAGAGCAGACTGCGGATGGTGTCGCGGTCATCCCCGTGCTGCAGAGAACA
  CTTCACTATGAGTGTATCGTTCTGGTGAAACAGTTCCGACCACCAATGGGGGGCTACTGC
  ATAGAGTTCCCTGCAGGTCTCATAGATGATGGTGAAACCCCAGAAGCAGCTGCTCTCCGG
  GAGCTTGAAGAAGAAACTGGCTACAAAGGGGACATTGCCGAATGTTCTCCAGCGGTCTGT
  ATGGACCCAGGCTTGTCAAACTGTACTATACACATCGTGACAGTCACCATTAACGGAGAT
  GATGCCGAAAACGCAAGGCCGAAGCCAAAGCCAGGGGATGGAGAGTTTGTGGAAGTCATT
  TCTTTACCCAAGAATGACCTGCTGCAGAGACTTGATGCTCTGGTAGCTGAAGAACATCTC
  ACAGTGGACGCCAGGGTCTATTCCTACGCTCTAGCACTGAAACATGCAAATGCAAAGCCA
  TTTGAAGTGCCCTTCTTGAAATTTTAAGCCCAAATATGACACTGGCCATTTTTGTAAACG
  AGACCACCAGGCCTTCTTCACTAAGACTTTGTATTCAACTTAGTTTAATGTAGATTTGCC
  ATTAGCTTTTTCGTAAAATAAAAGCACAGAACAGAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014142.2 unedited
  GTACTCTTGTCATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGAAAAAGAGCT
  TTAGTCTCGAAAGAGGAATTACCGAAGTGTCGAGAGAGGAATTTTAAGAAGTTTACAACT
  CCGTCTTCGCCCTAAACGCACGCTGACCCGGAAAGTAATCTCCTGAAGCTAGGTCAAAGG
  CGGGGGTTCTACGGATGCCGGAAGGAGGGTGCGCGCCCATCCTTTTAGCACCGCGAGAGG
  CGCCGGTGTTTCGAGCCGTGGCACCGGCATCGGCTGACACTGCTGCCTCCAGCTAGTTAT
  TTCGTCCTCTTCCGTTCTTCACCCCTACACCTTGGAGGTGAACTTCTCACCTGAGGGCTG
  TAAAGACTCGTTTGAAAATGGAGAGCCAAGAACCAACGGAATCTTCTCAGAATGGCAAAC
  AGTATATCATTTCAGAGGAGTTAATTTCAGAAGGAAAATGGGTCAAGCTTGAAAAAACAA
  CGTACATGGATCCTACTGGTAAAACTAGAACTTGGGAATCAGTGAAACGTACAACCAGGA
  AAGAGCAGACTGCGGATGGTGTCGCGGTCATCCCCGTGCTGCAGAGAACACTTCACTATG
  AGTGTATCGTTCTGGTGAAACAGTTCCGACCACCAATGGGGGGCTACTGCATAGAGTTCC
  CTGCAGGTCTCATAGATGATGGTGAAACCCCAGAAGCAGCTGCTCTCCGGGAGCTTGAAG
  AGAAACTGGCTACAAAGGGGACATTGCCGAATGTTCTCCAGCGGTCTGTTATGGACCCAG
  GCTTGTCAAACTGTACTATACACATCGTGACAGTCACCATTACGGAGATGATGCCGAAAA
  ACGCAGCCGAGCAAAGGCAGGGATGGAGAGTTTGGTGGAGTTCATTTCTTTACCAGGATG
  ACTGCTGCAAGGACTTGGATGCTTTTGGTAGCTGAGAGAACTTCTCACATG
• Restriction Sites: Please inquire
• ACCN: NM_014142
• ORF Size: 660 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014142.2, NP_054861.2
• RefSeq Size: 1224
• RefSeq ORF: 660
• Locus ID: 11164
• Domains: NUDIX
• Protein Pathways: Purine metabolism
• Gene Summary: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]