TTF1 (NKX2-1) (NM_001079668) Human Untagged Clone

CAT#: SC319511

NKX2 (untagged)-Human NK2 homeobox 1 (NKX2-1), transcript variant 1


  "NM_001079668" in other vectors (6)

Reconstitution Protocol

USD 760.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NKX2-1
Synonyms BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_001079668.1 GGCGACTGGGGCTCAGCGCAGCGAAGCCCGATGTGGTCCGGAGGCAGTGGGAAGGCGCGG
GGCTGGGAGGCCGCGGCGGGAGGGAGGAGCAGCCCCGGCAGGCTCAGCCGCCGCCGAATC
ATGTCGATGAGTCCAAAGCACACGACTCCGTTCTCAGTGTCTGACATCTTGAGTCCCCTG
GAGGAAAGCTACAAGAAAGTGGGCATGGAGGGCGGCGGCCTCGGGGCTCCGCTGGCGGCG
TACAGGCAGGGCCAGGCGGCACCGCCAACAGCGGCCATGCAGCAGCACGCCGTGGGGCAC
CACGGCGCCGTCACCGCCGCCTACCACATGACGGCGGCGGGGGTGCCCCAGCTCTCGCAC
TCCGCCGTGGGGGGCTACTGCAACGGCAACCTGGGCAACATGAGCGAGCTGCCGCCGTAC
CAGGACACCATGAGGAACAGCGCCTCTGGCCCCGGATGGTACGGCGCCAACCCAGACCCG
CGCTTCCCCGCCATCTCCCGCTTCATGGGCCCGGCGAGCGGCATGAACATGAGCGGCATG
GGCGGCCTGGGCTCGCTGGGGGACGTGAGCAAGAACATGGCCCCGCTGCCAAGCGCGCCG
CGCAGGAAGCGCCGGGTGCTCTTCTCGCAGGCGCAGGTGTACGAGCTGGAGCGACGCTTC
AAGCAACAGAAGTACCTGTCGGCGCCGGAGCGCGAGCACCTGGCCAGCATGATCCACCTG
ACGCCCACGCAGGTCAAGATCTGGTTCCAGAACCACCGCTACAAAATGAAGCGCCAGGCC
AAGGACAAGGCGGCGCAGCAGCAACTGCAGCAGGACAGCGGCGGCGGCGGGGGCGGCGGG
GGCACCGGGTGCCCGCAGCAGCAACAGGCTCAGCAGCAGTCGCCGCGACGCGTGGCGGTG
CCGGTCCTGGTGAAAGACGGCAAACCGTGCCAGGCGGGTGCCCCCGCGCCGGGCGCCGCC
AGCCTACAAGGCCACGCGCAGCAGCAGGCGCAGCACCAGGCGCAGGCCGCGCAGGCGGCG
GCAGCGGCCATCTCCGTGGGCAGCGGTGGCGCCGGCCTTGGCGCACACCCGGGCCACCAG
CCAGGCAGCGCAGGCCAGTCTCCGGACCTGGCGCACCACGCCGCCAGCCCCGCGGCGCTG
CAGGGCCAGGTATCCAGCCTGTCCCACCTGAACTCCTCGGGCTCGGACTACGGCACCATG
TCCTGCTCCACCTTGCTATACGGTCGGACCTGGTGAGAGGACGCCGGGCCGGCCCTAGCC
CAGCGCTCTGCCTCACCGCTTCCCTCCTGCCCGCCACACAGACCACCATCCACCGCTGCT
CCACGCGCTTCGACTTTTCTTAACAACCTGGCCGCGTTTAGACCAAGGAACAAAAAAACC
ACAAAGGCCAAACTGCTGGACGTCTTTCTTTTTTTCCCCCCCTAAAATTTGTGGGTTTTT
TTTTTAAAAAAAAGAAAATGAAAAACAACCAAGCGCATCCAATCTCAAGGAATCTTTAAG
CAGAGAAGGGCATAAAACAGCTTTGGGGTGTCTTTTTTTGGTGATTCAAATGGGTTTTCC
ACGCTAGGGCGGGGCACAGATTGGAGAGGGCTCTGTGCTGACATGGCTCTGGACTCTAAA
GACCAAACTTCACTCTGGGCACACTCTGCCAGCAAAGAGGACTCGCTTGTAAATACCAGG
ATTTTTTTTTTTTTTTGAAGGGAGGACGGGAGCTGGGGAGAGGAAAGAGTCTTCAACATA
ACCCACTTGTCACTGACACAAAGGAAGTGCCCCCTCCCCGGCACCCTCTGGCCGCCTAGG
CTCAGCGGCGACCGCCCTCCGCGAAAATAGTTTGTTTAATGTGAACTTGTAGCTGTAAAA
CGCTGTCAAAAGTTGGACTAAATGCCTAGTTTTTAGTAATCTGTACATTTTGTTGTAAAA
AGAAAAACCACTCCCAGTCCCCAGCCCTTCACATTTTTTATGGGCATTGACAAATCTGTG
TATATTATTTGGCAGTTTGGTATTTGCGGCGTCAGTCTTTTTCTGTTGTAACTTATGTAG
ATATTTGGCTTAAATATAGTTCCTAAGAAGCTTCTAATAAATTATACAAATTAAAAAGAT
TCTTTTTCTGATTAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_001079668
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001079668.1, NP_001073136.1
RefSeq Size 2183 bp
RefSeq ORF 1206 bp
Locus ID 7080
Cytogenetics 14q13.3
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Gene Summary 'This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]'
Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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