Claudin 3 (CLDN3) (NM_001306) Human Untagged Clone

CAT#: SC319526

CLDN3 (untagged)-Human claudin 3 (CLDN3)


  "NM_001306" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CLDN3
Synonyms C7orf1; CPE-R2; CPETR2; HRVP1; RVP1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_001306.2 CAAAGCCACAGGCAGGTGCAGGCGCAGCCGCGGCGAGAGCGTATGGAGCCGAGCCGTTAG
CGCGCGCCGTCGGTGAGTCAGTCCGTCCGTCCGTCCGTCCGTCGGGGCGCCGCAGCTCCC
GCCAGGCCCAGCGGCCCCGGCCCCTCGTCTCCCCGCACCCGGAGCCACCCGGTGGAGCGG
GCCTTGCCGCGGCAGCCATGTCCATGGGCCTGGAGATCACGGGCACCGCGCTGGCCGTGC
TGGGCTGGCTGGGCACCATCGTGTGCTGCGCGTTGCCCATGTGGCGCGTGTCGGCCTTCA
TCGGCAGCAACATCATCACGTCGCAGAACATCTGGGAGGGCCTGTGGATGAACTGCGTGG
TGCAGAGCACCGGCCAGATGCAGTGCAAGGTGTACGACTCGCTGCTGGCACTGCCACAGG
ACCTTCAGGCGGCCCGCGCCCTCATCGTGGTGGCCATCCTGCTGGCCGCCTTCGGGCTGC
TAGTGGCGCTGGTGGGCGCCCAGTGCACCAACTGCGTGCAGGACGACACGGCCAAGGCCA
AGATCACCATCGTGGCAGGCGTGCTGTTCCTTCTCGCCGCCCTGCTCACCCTCGTGCCGG
TGTCCTGGTCGGCCAACACCATTATCCGGGACTTCTACAACCCCGTGGTGCCCGAGGCGC
AGAAGCGCGAGATGGGCGCGGGCCTGTACGTGGGCTGGGCGGCCGCGGCGCTGCAGCTGC
TGGGGGGCGCGCTGCTCTGCTGCTCGTGTCCCCCACGCGAGAAGAAGTACACGGCCACCA
AGGTCGTCTACTCCGCGCCGCGCTCCACCGGCCCGGGAGCCAGCCTGGGCACAGGCTACG
ACCGCAAGGACTACGTCTAAGGGACAGACGCAGGGAGACCCCACCACCACCACCACCACC
AACACCACCACCACCACCGCGAGCTGGAGCGCGCACCAGGCCATCCAGCGTGCAGCCTTG
CCTCGGAGGCCAGCCCACCCCCAGAAGCCAGGAAGCCCCCGCGCTGGACTGGGGCAGCTT
CCCCAGCAGCCACGGCTTTGCGGGCCGGGCAGTCGACTTCGGGGCCCAGGGACCAACCTG
CATGGACTGTGAAACCTCACCCTTCTGGAGCACGGGGCCTGGGTGACCGCCAATACTTGA
CCACCCCGTCGAGCCCCATCGGGCCGCTGCCCCCATGCTCGCGCTGGGCAGGGACCGGCA
GCCCTGGAAGGGGCACTTGATATTTTTCAATAAAAGCCTTTCGTTTTGCAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_001306.2 unedited
GCGTACCTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCAAAGCCACA
GGCAGGTGCAGGCGCAGCCGCGGCGAGAGCGTATGGAGCCGAGCCGTTAGCGCGCGCCGT
CGGTGAGTCAGTCCGTCCGTCCGTCCGTCCGTCGGGGCGCCGCAGCTCCCGCCAGGCCCA
GCGGCCCCGGCCCCTCGTCTCCCCGCACCCGGAGCCACCCGGTGGAGCGGGCCTTGCCGC
GGCAGCCATGTCCATGGGCCTGGAGATCACGGGCACCGCGCTGGCCGTGCTGGGCTGGCT
GGGCACCATCGTGTGCTGCGCGTTGCCCATGTGGCGCGTGTCGGCCTTCATCGGCAGCAA
CATCATCACGTCGCAGAACATCTGGGAGGGCCTGTGGATGAACTGCGTGGTGCAGAGCAC
CGGCCAGATGCAGTGCAAGGTGTACGACTCGCTGCTGGCACTGCCACAGGACCTTCAGGC
GGCCCGCGCCCTCATCGTGGTGGCCATCCTGCTGGCCGCCTTCGGGCTGCTAGTGGCGCT
GGTGGGCGCCCAGTGCACCAACTGCGTGCAGGACGACACGGCCAAGGCCAAGATCACCAT
CGTGGCAGGCGTGCTGTTCCTTCTCGCCGCCCTGCTCACCCTCGTGCCGGTGTCCTGGTC
GGCCAACACCATTATCCGGGACTTCTACAACCCCGTGGTGCCCGAGGCGCAGAAGCGCGA
GATGGGCGCGGGCCTGTACTGAGCTGGGCGGCCCGCGGCGCTGCAGCTGCTGGGGGGCGC
GCTGCTCTGCTGCTCGTGTCCCCCCACGCGAGAAGAAGTACACGGCCACCAAAGGTCGTC
TACTCCGGCGCCGGCGCTCCACCGCCCGGGAGCCAGCCTGGGCACAGGCTACGACGCAGA
CTACGTTCTAGGACAGAACCCAGGGAGGAACCACAACACAACCACCACCAAAACACCACC
A
Restriction Sites Please inquire     
ACCN NM_001306
ORF Size 663 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_001306.2, NP_001297.1
RefSeq Size 1294
RefSeq ORF 663
Locus ID 1365
Domains PMP22_Claudin
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Gene Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

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