NEI3 (NEIL3) (NM_018248) Human Untagged Clone

CAT#: SC319567

NEIL3 (untagged)-Human nei endonuclease VIII-like 3 (E. coli) (NEIL3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NEIL3
• Synonyms: FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_018248.1 GCGCAGCGTTGAGTTGCACAGCGGTATTCTCACCAGGCCCTGCAATCGGTGGGCCACAGT
  GCCGGCCACAGAGATGGTGGAAGGACCAGGCTGTACTCTGAATGGAGAGAAGATTCGAGC
  GCGGGTGCTCCCGGGCCAGGCGGTGACCGGCGTGCGGGGAAGCGCTCTGCGGAGTCTGCA
  GGGCCGCGCCTTGCGGCTCGCAGCCTCCACGGTTGTGGTCTCCCCGCAGGCTGCTGCACT
  GAATAATGATTCCAGCCAGAATGTCTTGAGCCTGTTTAATGGATATGTTTACAGTGGCGT
  GGAAACTTTGGGGAAGGAGCTCTTTATGTACTTTGGACCAAAAGCTTTACGGATTCATTT
  CGGAATGAAAGGCTTCATCATGATTAATCCACTTGAGTATAAATATAAAAATGGAGCTTC
  TCGTGTTTTGGAAGTGCAGCTCACCAAAGATTTGATTTGTTTCTTTGACTCATCAGTAGA
  ACTCAGAAACTCAATGGAAAGCCAACAGAGAATAAGAATGATGAAAGAATTAGATGTATG
  TTCACCTGAATTTAGTTTCTTGAGAGCAGAAAGTGAAGTTAAAAAACAGAAAGGCCGGAT
  GCTAGGTGATGTGCTAATGGATCAGAACGTATTGCCTGGAGTAGGGAACATCATCAAAAA
  TGAAGCTCTCTTTGACAGTGGTCTCCACCCAGCTGTTAAAGTTTGTCAATTAACAGATGA
  ACAGATCCATCACCTCATGAAAATGATACGTGATTTCAGCATTCTCTTTTACAGGTGCCG
  TAAAGCAGGACTTGCTCTCTCTAAACACTATAAGGTTTACAAGCGTCCCAATTGTGGTCA
  GTGCCACTGCAGAATAACTGTGTGCCGCTTTGGGGACAATAACAGAATGACATATTTCTG
  TCCTCACTGTCAAAAAGAAAATCCTCAACATGTTGACATATGCAAGCTACCGACTAGAAA
  TACTATAATCAGTTGGACATCTAGCAGGGTGGATCATGTTATGGACTCCGTGGCTCGGAA
  GTCGGAAGAGCACTGGACCTGTGTGGTGTGTACTTTAATCAATAAGCCCTCTTCTAAGGC
  ATGTGATGCTTGCTTGACCTCAAGGCCTATTGATTCAGTGCTCAAGAGTGAAGAAAATTC
  TACTGTCTTTAGCCACTTAATGAAGTACCCGTGTAATACTTTTGGAAAACCTCATACAGA
  AGTCAAGATCAACAGGAAAACTGCATTTGGAACTACAACTCTTGTCTTGACTGATTTTAG
  CAATAAATCCAGTACTTTGGAAAGAAAAACAAAGCAAAACCAGATACTAGATGAGGAGTT
  TCAAAACTCTCCTCCTGCTAGTGTGTGTTTGAATGATATACAGCACCCCTCCAAGAAGAC
  AACAAACGATATAACTCAACTATCCAGCAAAGTAAACATATCACCTACAATCAGTTCAGA
  ATCTAAATTATTTAGTCCAGCACATAAAAAACCGAAAACAGCCCACTACTCATCACCAGA
  GCTTAAAAGCTGCAACCCTGGATATTCTAACAGTGAACTTCAAATTAATATGACAGATGG
  CCCTCGTACCTTAAATCCTGACAGCCCTCGCTGCAGTAAACACAACCGCCTCTGCATTCT
  CCGAGTTGTGAGGAAGGATGGGGAAAACAAGGGCAGGCAGTTTTATGCCTGTCCTCTACC
  TAGAGAAGCACAATGTGGATTTTTTGAATGGGCAGATTTGTCCTTCCCATTCTGCAACCA
  TGGCAAGCGTTCCACCATGAAAACAGTATTGAAGATTGGACCTAACAATGGAAAGAATTT
  TTTTGTGTGTCCTCTTGGGAAGGAAAAACAATGCAATTTTTTCCAGTGGGCAGAAAATGG
  GCCAGGAATAAAAATTATTCCTGGATGCTAATATCTGTAGATTCTCTGGCATTTAGTCTC
  TTCAAACTGTGTATAATGTTTGGTCCTCCTCTGTTTCATAGAAAAGTCATAGAATATGAT
  ACATTGAAAAGTTACTGCAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018248.1 unedited
  TAGTTACATAGATGTTATACGACCTCCCTATAGGGCGGCTCGGGAATCTCGGCACGAGGG
  CGCAGCGTTTGAGTCTGCACAGCGGTATTTCTCACCAGGCCCTGCAATCGGTGGGCCACA
  GTGCCGGCCACAGAGATGGTGGAAGGACCAGGCTGTACTCTGAATGGAGAGAAGATTCGA
  GCGCGGGTGCTCCCGGGCCAGGCGGTGACCGGCGTGCGGGGAAGCGCTCTGCGGAGTCTG
  CAGGGCCGCGCCTTGCGGCTCGCAGCCTCCACGGTTGTGGTCTCCCCGCAGGCTGCTGCA
  CTGAATAATGATTCCAGCCAGAATGTCTTGAGCCTGTTTAATGGATATGTTTACAGTGGC
  GTGGAAACTTTGGGGAAGGAGCTCTTTATGTACTTTGGACCAAAAGCTTTACGGATTCAT
  TTCGGAATGAAAGGCTTCATCATGATTAATCCACTTGAGTATAAATATAAAAATGGAGCT
  TCTCGTGTTTTGGAAGTGCAGCTCACCAAAGATTTGATTTGTTTCTTTGACTCATCAGTA
  GAACTCAGAAACTCAATGGAAAGCCAACAGAGAATAAGAATGATGAAAGAATTAGATGTA
  TGTTCACCTGAATTTAGTTTCTTGAGAGCAGAAAGTGAAGTTAAAAAACAGAAAGGCCGG
  ATGCTAGTGATGTGCTAATGGATCAGACGTATTGCCTGGAGTAGGGAACATCATCAAAAA
  TGAAGCTCTCTTTGACAGTGGTCCTCCACCCAGCTGTAAAGTTTGTCAATTAACAGATGA
  ACAGATCCATCACTCATGAAATGATACGTGATTTCAGCATTCTCTTTACAGTGCGTAAGC
  AGACTGCTCTCTCTAACACTATAGGTTACAGCGTTCCATTGTGGTCATGCCCTGCAGATA
  CTGGTGGTGGCGGCTTGGGG
• Restriction Sites: Please inquire
• ACCN: NM_018248
• ORF Size: 1818 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_018248.1, NP_060718.1
• RefSeq Size: 2273
• RefSeq ORF: 1818
• Locus ID: 55247
• Domains: Fapy_DNA_glyco, zf-RanBP
• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair
• Gene Summary: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]). [supplied by OMIM, Mar 2008]