PPP1R14A (NM_033256) Human Untagged Clone

CAT#: SC319588

PPP1R14A (untagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 14A (PPP1R14A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPP1R14A
• Synonyms: CPI-17; CPI17; PPP1INL
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_033256.1 CTGGGTCCAGCAGCGCGATGGCAGCTCAGCGGCTGGGCAAGCGCGTGCTGAGCAAGCTGC
  AGTCTCCATCGCGGGCCCGCGGGCCAGGGGGCAGTCCCGGGGGGCTGCAGAAGCGGCACG
  CGCGCGTCACCGTCAAGTATGACCGGCGGGAGCTGCAGCGGCGGCTGGACGTGGAGAAGT
  GGATCGACGGGCGCCTGGAGGAGCTGTACCGCGGCATGGAGGCAGACATGCCCGATGAGA
  TCAACATTGATGAATTGTTGGAGTTAGAGAGTGAAGAGGAGAGAAGCCGGAAAATCCAGG
  GACTCCTGAAGTCATGTGGGAAACCTGTCGAGGACTTCATCCAGGAGCTGCTGGCAAAGC
  TTCAAGGCCTCCACAGGCAGCCCGGCCTCCGCCAGCCAAGCCCCTCCCACGACGGCAGCC
  TCAGCCCCCTCCAGGACCGGGCCCGGACTGCTCACCCCTGACCCTCTTGCACTCTCCCTG
  CCCCCCGGACGCCGCCCAGCTTGCTTGTGTATAAGTTGTATTTAATGGTTCTGTAACAAT
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033256.1 unedited
  CCGTGTACTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGCTGGGTCCA
  GCAGCGCGATGGCAGCTCAGCGGCTGGGCAAGCGCGTGCTGAGCAAGCTGCAGTCTCCAT
  CGCGGGCCCGCGGGCCAGGGGGCAGTCCCGGGGGGCTGCAGAAGCGGCACGCGCGCGTCA
  CCGTCAAGTATGACCGGCGGGAGCTGCAGCGGCGGCTGGACGTGGAGAAGTGGATCGACG
  GGCGCCTGGAGGAGCTGTACCGCGGCATGGAGGCAGACATGCCCGATGAGATCAACATTG
  ATGAATTGTTGGAGTTAGAGAGTGAAGAGGAGAGAAGCCGGAAAATCCAGGGACTCCTGA
  AGTCATGTGGGAAACCTGTCGAGGACTTCATCCAGGAGCTGCTGGCAAAGCTTCAAGGCC
  TCCACAGGCAGCCCGGCCTCCGCCAGCCAAGCCCCTCCCACGACGGCAGCCTCAGCCCCC
  TCCAGGACCGGGCCCGGACTGCTCACCCCTGACCCTCTTGCACTCTCCCTGCCCCCCGGA
  CGCCGCCCAGCTTGCTTGTGTATAAGTTGTATTTAATGGTTCTGTAACAATAAAAAAAAA
  AAAAAAAAAAAAAAACTCTCGAGGTTTAAACGGCCGGCCCGCGGTCATAGCTGTTTCCTG
  AACAGATCCCGGGTGGCATCCCTGTGACCCCCTCCCCAGTGCCTCTCCTGGCCCTGGAGT
  TGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGA
  CTAGTGTCCTCTATAATATATGGGTGAGGGGGGTGGTATGGACAGGCCCAACTGCAAACA
  CTGTACGCCTGCGGTCTATGGGAACCACTGAATGCATGCCATCTGTCTCATGAATCCCGC
  CTCTGGTCAGCATGTACTCTGAGTCCATCTAGAGAGGC
• Restriction Sites: Please inquire
• ACCN: NM_033256
• ORF Size: 444 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_033256.1, NP_150281.1
• RefSeq Size: 723
• RefSeq ORF: 444
• Locus ID: 94274
• Domains: PP1_inhibitor
• Protein Families: Druggable Genome
• Protein Pathways: Vascular smooth muscle contraction
• Gene Summary: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]
  Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1, also known as CPI-17alpha).