BBS2 (NM_031885) Human Untagged Clone

CAT#: SC319657

BBS2 (untagged)-Human Bardet-Biedl syndrome 2 (BBS2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BBS2
• Synonyms: BBS; RP74
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_031885.2 GTCCGGCCTGAGGCGGCTGGGGCCGCGCAGGTAGTGTCCCTGCACTTCTTGCCCGGGCGC
  GTGAGGCCAGCTCCGCTGCGCTTGTCTCCAGCTTCCAGCCCTCCTCCCCTAAGCCGCCGC
  CATCATGCTGCTGCCTGTGTTCACCCTGAAACTGCGCCACAAAATCAGCCCCCGAATGGT
  GGCCATAGGGCGCTACGACGGGACTCACCCGTGCCTGGCGGCCGCCACCCAAACGGGCAA
  GGTTTTTATTCATAATCCTCATACACGGAACCAGCATGTCAGTGCATCCAGGGTCTTCCA
  GAGCCCCCTGGAATCTGATGTTTCTCTTCTCAACATTAACCAGGCAGTCAGCTGTCTGAC
  TGCAGGCGTATTGAACCCTGAGCTTGGCTATGATGCCCTTTTAGTGGGGACACAGACTAA
  TCTTTTGGCTTATGATGTCTACAATAATTCGGATTTGTTCTACAGAGAGGTAGCAGATGG
  GGCAAATGTAGTTGTGCTGGGGACATTGGGAGACATTTCTTCCCCTCTTGCGATTATTGG
  TGGCAATTGTGCTCTGCAAGGTTTCAATCATGAAGGAAGTGATCTCTTTTGGACGGTTAC
  TGGAGACAATGTTAATTCCTTGGCCTTGTGTGACTTTGATGGTGATGGAAAGAAAGAGCT
  TCTTGTTGGATCTGAGGATTTTGATATCCGAGTTTTTAAGGAAGATGAGATTGTGGCAGA
  AATGACAGAAACAGAGATAGTCACCTCTCTTTGTCCCATGTATGGCAGTCGATTTGGTTA
  TGCCCTTTCCAATGGCACAGTTGGAGTTTATGACAAAACATCCCGATACTGGAGAATTAA
  ATCGAAAAATCATGCCATGAGCATTCATGCTTTTGACCTTAATTCTGATGGAGTGAATGA
  ACTGATAACTGGTTGGTCCAATGGGAAGGTTGATGCTCGAAGTGACCGAACTGGGGAGGT
  CATCTTTAAGGACAATTTTTCTTCTGCAATTGCCGGTGTGGTAGAGGGAGATTACCGGAT
  GGATGGCCACATACAGTTAATCTGCTGCTCAGTGGATGGGGAAATCCGGGGCTACCTGCC
  TGGCACGGCTGAGATGAGGGGCAACCTCATGGACACCAGTGCAGAGCAGGACCTGATCCG
  AGAGCTGAGTCAGAAGAAGCAGAATCTGTTGCTGGAACTCCGTAACTATGAGGAAAATGC
  CAAGGCTGAATTGGCCAGTCCACTGAACGAGGCTGATGGGCATCGGGGCATAATCCCAGC
  CAATACCAGGCTCCACACCACGCTCTCAGTCAGCCTGGGGAATGAGACCCAAACTGCTCA
  TACAGAATTACGCATTTCCACTTCTAATGACACCATCATCCGAGCAGTATTGATTTTTGC
  AGAAGGAATTTTTACAGGTGAAAGCCACGTGGTACATCCCAGCATTCACAACCTCTCCAG
  TTCCATCTGCATCCCTATTGTGCCTCCCAAAGATGTCCCTGTGGATCTGCACTTGAAGGC
  ATTCGTGGGTTACAGAAGCAGCACCCAGTTTCATGTATTTGAATCGACAAGACAGCTCCC
  TCGATTCTCCATGTATGCGCTGACCAGCCTGGACCCTGCCAGTGAGCCAATCAGTTATGT
  TAACTTTACCATTGCAGAACGGGCACAGAGGGTTGTTGTATGGCTCGGTCAGAACTTTCT
  GTTACCAGAAGACACTCACATTCAGAATGCTCCATTTCAAGTGTGTTTCACATCTTTACG
  GAATGGCGGCCACCTGCATATAAAAATAAAACTTAGTGGAGAGATCACTATAAATACTGA
  TGATATTGATTTGGCTGGTGATATCATCCAGTCAATGGCATCATTTTTTGCTATTGAAGA
  CCTTCAAGTAGAAGCGGATTTTCCTGTCTATTTTGAGGAATTACGAAAGGTGCTAGTTAA
  GGTGGATGAATATCATTCAGTGCATCAGAAGCTCAGTGCTGATATGGCTGATCATTCTAA
  TTTGATCCGAAGTTTGCTGGTCGGAGCTGAGGATGCTCGTCTGATGAGGGACATGAAAAC
  AATGAAGAGTCGTTATATGGAACTCTATGACCTTAATAGAGACTTGCTAAATGGATATAA
  AATTCGCTGTAACAATCACACAGAGCTGTTGGGAAACCTCAAAGCAGTAAATCAAGCAAT
  TCAAAGAGCAGGTCGTCTGCGGGTTGGAAAACCAAAGAACCAGGTGATCACTGCTTGTCG
  GGATGCAATTCGAAGCAATAACATCAACACACTGTTCAAAATCATGCGAGTGGGGACAGC
  TTCTTCCTAGGTGAGGAAAATACAGGTCATGAAGTTCCTGGCAAAGATTTTCTGTTAAAA
  ACCTATGCTGGTTTGCTTTGGATCACACCCTGGTGAACCCCGGGTGCTAAGAATGAAAAT
  AACCTTGGTGAGTTGTACAAATTAAAGACAAAGAACTACATGTGAAAAAAAAAAAAAAAA
  AA
• Restriction Sites: Please inquire
• ACCN: NM_031885
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_031885.2, NP_114091.2
• RefSeq Size: 2978 bp
• RefSeq ORF: 2166 bp
• Locus ID: 583
• Cytogenetics: 16q13
• Domains: FG-GAP
• Protein Families: Druggable Genome
• Gene Summary: 'This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.[provided by RefSeq, Oct 2014]'