NT5C3 (NT5C3A) (NM_016489) Human Untagged Clone

CAT#: SC319672

NT5C3 (untagged)-Human 5'-nucleotidase, cytosolic III (NT5C3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NT5C3A
• Synonyms: cN-III; hUMP1; NT5C3; P5'N-1; P5N-1; p36; PN-I; POMP; PSN1; UMPH; UMPH1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016489.11 GGGGCTTTTGCTGGTGTAGCTCGTCCGGTTACCTTCAGGAAGATTGGATAACCAAGAAAT
  GACTAATCAAGAGTCTGCCGTACATGTGAAAATGATGCCAGAATTCCAGAAAAGTTCAGT
  TCGAATCAAGAACCCTACAAGAGTAGAAGAAATTATCTGTGGTCTTATCAAAGGAGGAGC
  TGCCAAACTTCAGATAATAACGGACTTTGATATGACACTCAGTAGATTTTCATATAAAGG
  GAAAAGATGCCCAACATGTCATAATATCATTGACAACTGTAAGCTGGTTACAGATGAATG
  TAGAAAAAAGTTATTGCAACTAAAGGAAAAATACTACGCTATTGAAGTTGATCCTGTTCT
  TACTGTAGAAGAGAAGTACCCTTATATGGTGGAATGGTATACTAAATCACATGGTTTGCT
  TGTTCAGCAAGCTTTACCAAAAGCTAAACTTAAAGAAATTGTGGCAGAATCTGACGTTAT
  GCTCAAAGAAGGATATGAGAATTTCTTTGATAAGCTCCAACAACATAGCATCCCCGTGTT
  CATATTTTCGGCTGGAATCGGCGATGTACTAGAGGAAGTTATTCGTCAAGCTGGTGTTTA
  TCATCCCAATGTCAAAGTTGTGTCCAATTTTATGGATTTTGATGAAACTGGGGTGCTCAA
  AGGATTTAAAGGAGAACTAATTCATGTATTTAACAAACATGATGGTGCCTTGAGGAATAC
  AGAATATTTCAATCAACTAAAAGACAATAGTAACATAATTCTTCTGGGAGACTCCCAAGG
  AGACTTAAGAATGGCAGATGGAGTGGCCAATGTTGAGCACATTCTGAAAATTGGATATCT
  AAATGATAGAGTGGATGAGCTTTTAGAAAAGTACATGGACTCTTATGATATTGTTTTAGT
  ACAAGATGAATCATTAGAAGTAGCCAACTCTATTTTACAGAAGATTCTATAAACAAGCAT
  TCTCCAAGAAGACCTCTCTCCTGTGGGTGCAATTGAACTGTTCATCCGTTCATCTTGCTG
  AGAGACTTATTTATAATATATCCTTACTCTCGAAGTGTTCCCTTTGTATAACTGAAGTAT
  TTTCAGATATGGTGAATGCATTGACTGGAAGCTCCTTTTCTCCACCTCTCTCAACACACT
  CCTCACCGTATCTTTTAACCCATTTTAAAAAAAAAAATCTTAAAGCCAAAATTAGAAAAA
  TAACTCCCTACTTTTCCAAAGTGAATTTTGTAGTTTAATGTTATCATGCAGCTTTTGAGG
  AGTCTTTTACACTGGGAAAGTTTGTAGAAATTTTAAAATAAGTTTTATGAAATGGTGAAA
  TAATATGCATGATTTTAAGTATTGCCATTTTTGTAATTTGGGTTATTATGCTGATGGTAT
  CACCATCTCTTGAAATTGTGTTAGGTTTGGTTATTTTGTCTGGGGAAAAAATATTTACTG
  GAAAAGACTAGCAGTTAGTGTTGGAAAAACCTGGTGGTGTTTACAATGTTGCTAATCATT
  ACAAAACATTCTATATTGAAGCACTGATAATAAATATGAAATCCAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016489.11 unedited
  GGGTATCATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGG
  CTTTTGCTGGTGTAGCTCGTCCGGTTACCTTCAGGAAGATTGGATAACCAAGAAATGACT
  AATCAAGAGTCTGCCGTACATGTGAAAATGATGCCAGAATTCCAGAAAAGTTCAGTTCGA
  ATCAAGAACCCTACAAGAGTAGAAGAAATTATCTGTGGTCTTATCAAAGGAGGAGCTGCC
  AAACTTCAGATAATAACGGACTTTGATATGACACTCAGTAGATTTTCATATAAAGGGAAA
  AGATGCCCAACATGTCATAATATCATTGACAACTGTAAGCTGGTTACAGATGAATGTAGA
  AAAAAGTTATTGCAACTAAAGGAAAAATACTACGCTATTGAAGTTGATCCTGTTCTTACT
  GTAGAAGAGAAGTACCCTTATATGGTGGAATGGTATACTAAATCACATGGTTTGCTTGTT
  CAGCAAGCTTTACCAAAAGCTAAACTTAAAGAAATTGTGGCAGAATCTGACGTTATGCTC
  AAAGAAGGATATGAGAATTTCTTTGATAAGCTCCAACAACATAGCATCCCCGTGTTCATA
  TTTTCGGCTGGAATCGGCGATGTACTAGAGGAAGTTATTCGTCAAGCTGGTGTTTATCAT
  CCCAATGTCAAAGTTGTGTCCAATTTTATGGATTTTGATGAAACTGGGGTGCTCAAAGGA
  TTTAAAGGAGAACTAATTCATGTATTTAACAAACATGATGGTGCCTTGAGATACAGATAT
  TTCAATCAACTAAAGACATAGTACATATTCTCTGGGAGACTCCAGAGACTTAGATGCAGA
  TGAGTGCATGTGAGCACATCTGAAAATGATATCTAATGATGAGTGATGAGCTTTAGAAAG
  TACATGACTTCTATTGATTTGTTTAGTACAGATGATCATAGAGTAGCCACCTCTA
• Restriction Sites: Please inquire
• ACCN: NM_016489
• ORF Size: 894 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016489.11, NP_057573.2
• RefSeq Size: 1552
• RefSeq ORF: 894
• Locus ID: 51251
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism
• Gene Summary: This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4. [provided by RefSeq, Mar 2012]
  Transcript Variant: This variant (3) differs in the 5' UTR, includes an alternate internal exon in the 5' region, and initiates translation at an alternate start codon, compared to variant 1. Variants 2 and 3 encode the same isoform (2), which is shorter and has a distinct N-terminus, compared to isoform 1.