P2Y12 (P2RY12) (NM_022788) Human Untagged Clone

CAT#: SC319680

P2RY12 (untagged)-Human purinergic receptor P2Y, G-protein coupled, 12 (P2RY12), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: P2RY12
• Synonyms: ADPG-R; BDPLT8; HORK3; P2T(AC); P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; SP1999
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022788.3 ATCACAATCAGAAGACAGGAGCTGCAGAACAGAACACTTTCTCATGTCCAGGGTCAGATT
  ACAAGAGCACTCAAGACTTTACTGACGAAAACTCAGGAAATCCTCTATCACAAAGAGGTT
  TGGCAACTAAACTAAGACATTAAAAGGAAAATACCAGATGCCACTCTGCAGGCTGCAATA
  ACTACTACTTACTGGATACATTCAAACCCTCCAGAATCAACAGTTATCAGGTAACCAACA
  AGAAATGCAAGCCGTCGACAATCTCACCTCTGCGCCTGGGAACACCAGTCTGTGCACCAG
  AGACTACAAAATCACCCAGGTCCTCTTCCCACTGCTCTACACTGTCCTGTTTTTTGTTGG
  ACTTATCACAAATGGCCTGGCGATGAGGATTTTCTTTCAAATCCGGAGTAAATCAAACTT
  TATTATTTTTCTTAAGAACACAGTCATTTCTGATCTTCTCATGATTCTGACTTTTCCATT
  CAAAATTCTTAGTGATGCCAAACTGGGAACAGGACCACTGAGAACTTTTGTGTGTCAAGT
  TACCTCCGTCATATTTTATTTCACAATGTATATCAGTATTTCATTCCTGGGACTGATAAC
  TATCGATCGCTACCAGAAGACCACCAGGCCATTTAAAACATCCAACCCCAAAAATCTCTT
  GGGGGCTAAGATTCTCTCTGTTGTCATCTGGGCATTCATGTTCTTACTCTCTTTGCCTAA
  CATGATTCTGACCAACAGGCAGCCGAGAGACAAGAATGTGAAGAAATGCTCTTTCCTTAA
  ATCAGAGTTCGGTCTAGTCTGGCATGAAATAGTAAATTACATCTGTCAAGTCATTTTCTG
  GATTAATTTCTTAATTGTTATTGTATGTTATACACTCATTACAAAAGAACTGTACCGGTC
  ATACGTAAGAACGAGGGGTGTAGGTAAAGTCCCCAGGAAAAAGGTGAACGTCAAAGTTTT
  CATTATCATTGCTGTATTCTTTATTTGTTTTGTTCCTTTCCATTTTGCCCGAATTCCTTA
  CACCCTGAGCCAAACCCGGGATGTCTTTGACTGCACTGCTGAAAATACTCTGTTCTATGT
  GAAAGAGAGCACTCTGTGGTTAACTTCCTTAAATGCATGCCTGGATCCGTTCATCTATTT
  TTTCCTTTGCAAGTCCTTCAGAAATTCCTTGATAAGTATGCTGAAGTGCCCCAATTCTGC
  AACATCTCTGTCCCAGGACAATAGGAAAAAAGAACAGGATGGTGGTGACCCAAATGAAGA
  GACTCCAATGTAAACAAATTAACTAAGGAAATATTTCAATCTCTTTGTGTTCAGAACTCG
  TTAAAGCAAAGCGCTAAGTAAAAATATTAACTGACGAAGAAGCAACTAAGTTAATAATAA
  TGACTCTAAAGAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022788.3 unedited
  AGGGGGGGGGCAGGCGGGCCGATGGTCTTAACAACTACTGGCGGCCGAAAATCGGCCTTA
  CGGCCGGGATCACAATCAGAAGACAGGAGCTGCAGAACAGAACACTTTCTCATGTCCAGG
  GTCAGATTACAAGAGCACTCAAGACTTTACTGACGAAAACTCAGGAAATCCTCTATCACA
  AAGAGGTTTGGCAACTAAACTAAGACATTAAAAGGAAAATACCAGATGCCACTCTGCAGG
  CTGCAATAACTACTACTTACTGGATACATTCAAACCCTCCAGAATCAACAGTTATCAGGT
  AACCAACAAGAAATGCAAGCCGTCGACAATCTCACCTCTGCGCCTGGGAACACCAGTCTG
  TGCACCAGAGACTACAAAATCACCCAGGTCCTCTTCCCACTGCTCTACACTGTCCTGTTT
  TTTGTTGGACTTATCACAAATGGCCTGGCGATGAGGATTTTCTTTCAAATCCGGAGTAAA
  TCAAACTTTATTATTTTTCTTAAGAACACAGTCATTTCTGATCTTCTCATGATTCTGACT
  TTTCCATTCAAAATTCTTAGTGATGCCAAACTGGGAACAGGACCACTGAGAACTTTTGTG
  TGTCAAGTTACCTCCGTCATATTTTATTTCACAATGTATATCAGTATTTCATTCCTGGGA
  CTGATAACTATCGATCGCTACCAGAAGACCACCAGGCCATTTAAAACATCCACCCCAAAA
  TCTCTTGGGGGCTAAGATTCTCTCTGTTGTCATCTGGGCATTCATGTTCTTACTCTCTTT
  GCCTAACATGATTCTGACCAACAGGCAGCCGAGAGACAAGAATTGTGAAGAATGCTCTTC
  TTAATCAGAGTTCGTTCTAGTCTGCATGAAATAGTAAATACATCTGTCAGTCATTTCTGA
  TAATTCTTATTGTATTGTAGTTTACCTCTTACAAAGAACTGACGTCCAACGTAAAACGAG
  GGGTGTAGTAAGTTCCCAGAAAAGTGAACGCTCAAG
• Restriction Sites: Please inquire
• ACCN: NM_022788
• ORF Size: 1029 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_022788.3, NP_073625.1
• RefSeq Size: 1502
• RefSeq ORF: 1029
• Locus ID: 64805
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.