UBE1C (UBA3) (NM_003968) Human Untagged Clone

CAT#: SC319697

UBA3 (untagged)-Human ubiquitin-like modifier activating enzyme 3 (UBA3), transcript variant 1


  "NM_003968" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol UBA3
Synonyms hUBA3; NAE2; UBE1C
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_003968.3 GGGAGAGGCGGAGAACAATATGGCGGATGGCGAGGAGCCGGAGAGGAAAAGAAGGAGAAT
AGAGGAGCTGCTGGCTGAGAAAATGGCTGTTGATGGTGGGTGTGGGGACACTGGAGACTG
GGAAGGTCGCTGGAACCATGTAAAGAAGTTCCTCGAGCGATCTGGACCCTTCACACACCC
TGATTTCGAACCGAGCACTGAATCTCTCCAGTTCTTGTTAGATACATGTAAAGTTCTAGT
CATTGGAGCTGGCGGCTTAGGATGTGAGCTCCTGAAAAATCTGGCCTTGTCTGGTTTTAG
ACAGATTCATGTTATAGATATGGACACTATAGATGTTTCCAATCTAAATAGGCAGTTTTT
ATTTAGGCCTAAAGATATTGGAAGACCTAAGGCTGAAGTTGCTGCAGAATTTCTAAATGA
CAGAGTTCCTAATTGCAATGTAGTTCCACATTTCAACAAGATTCAAGATTTTAACGACAC
TTTCTATCGACAATTTCATATTATTGTATGTGGACTGGACTCTATCATCGCCAGAAGATG
GATAAATGGCATGCTGATATCTCTTCTAAATTATGAAGATGGTGTCTTAGATCCAAGCTC
CATTGTCCCTTTGATAGATGGGGGGACAGAAGGTTTTAAAGGAAATGCCCGGGTGATTCT
GCCTGGAATGACTGCTTGTATCGAATGCACGCTGGAACTTTATCCACCACAGGTTAATTT
TCCCATGTGCACCATTGCATCTATGCCCAGGCTACCAGAACACTGTATTGAGTATGTAAG
GATGTTGCAGTGGCCTAAGGAGCAGCCTTTTGGAGAAGGGGTTCCATTAGATGGAGATGA
TCCTGAACATATACAATGGATTTTCCAAAAATCCCTAGAGAGAGCATCACAATATAATAT
TAGGGGTGTTACGTATAGGCTCACTCAAGGGGTAGTAAAAAGAATCATTCCTGCAGTAGC
TTCCACAAATGCAGTCATTGCAGCTGTGTGTGCCACTGAGGTTTTTAAAATAGCCACAAG
TGCATACATTCCCTTGAATAATTACTTGGTGTTTAATGATGTAGATGGGCTGTATACATA
CACATTTGAAGCAGAAAGAAAGGAAAACTGCCCAGCTTGTAGCCAGCTTCCTCAAAATAT
TCAGTTTTCTCCATCAGCTAAACTACAGGAGGTTTTGGATTATCTAACCAATAGTGCTTC
TCTGCAAATGAAATCTCCAGCCATCACAGCCACCCTAGAGGGAAAAAATAGAACACTTTA
CTTACAGTCGGTAACCTCTATTGAAGAACGAACAAGGCCAAATCTCTCCAAAACATTGAA
AGAATTGGGGCTTGTTGATGGACAAGAACTGGCGGTTGCTGATGTCACCACCCCACAGAC
TGTACTATTCAAACTTCATTTTACTTCTTAAGGAAAATCTCCACATAATAGAAAACTCAT
GGAAATAATATACTTTGTGGATGCTAAGAAGTTGAATCGATGTCATTTTTAGCAATAGTG
TTGCCACGATTTGTCTTTTTTTTATATAATGAACCACTCTTTTTTAACTTTGTAACCTTC
CCTTGAAGACAGAATTTTGGTGTTGGTGCTTGTAAGCATTTTCATTAATAATATGAGAAA
TGATACCTGGAGAGAGAGATTATGAGCAAATGTATTGCTTCTTTTAGAGGAGGAAGCATA
CAACCTCTTTTGTGTGAATTTTGTTATTATGGTCAAAGAATGCATTCCTAAGTTTTCATT
TGAGTACCCAAATACACAAAAGGTGTCCCTTTAAGGAAAATAAAGAATTAAGTTTTAAAT
CAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_003968.3 unedited
AGGACGAGCATGATGTGTTCTTAACTGCTCTAGGGCGGCCGGAATCGGCCATTACGGCCG
GGAGAGGCGGAGAACAATATGGCGGATGGCGAGGAGCCGGAGAGGAAAAGAAGGAGAATA
GAGGAGCTGCTGGCTGAGAAAATGGCTGTTGATGGTGGGTGTGGGGACACTGGAGACTGG
GAAGGTCGCTGGAACCATGTAAAGAAGTTCCTCGAGCGATCTGGACCCTTCACACACCCT
GATTTCGAACCGAGCACTGAATCTCTCCAGTTCTTGTTAGATACATGTAAAGTTCTAGTC
ATTGGAGCTGGCGGCTTAGGATGTGAGCTCCTGAAAAATCTGGCCTTGTCTGGTTTTAGA
CAGATTCATGTTATAGATATGGACACTATAGATGTTTCCAATCTAAATAGGCAGTTTTTA
TTTAGGCCTAAAGATATTGGAAGACCTAAGGCTGAAGTTGCTGCAGAATTTCTAAATGAC
AGAGTTCCTAATTGCAATGTAGTTCCACATTTCAACAAGATTCAAGATTTTAACGACACT
TTCTATCGACAATTTCATATTATTGTATGTGGACTGGACTCTATCATCGCCAGAAGATGG
ATAAATGGCATGCTGATATCTCTTCTAAATTATGAAGATGGTGTCTTAGATCCAAGCTCC
ATTGTCCCTTTGATAGATGGGGGGACAGAAGTTTTAAAGGAAATGCCCGGTGATTCTGCC
TGGAATGACTGCTTGTATCGAATGCACGCTGGAACTTTATCCACCACAGGTTAATTTTCC
ATGTCACATTGCATTCTATGCCCAGCTACCAGACACTGATTGATATTGTAAGATGTTGCA
TGGCTACGAGCAGCTTTGGAGAGGTTCCATAGAATGGAGAAGATCCTGACATATAAAATG
GATTTTCAAAATCCCTAAGA
Restriction Sites Please inquire     
ACCN NM_003968
ORF Size 1392 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_003968.3, NP_003959.3
RefSeq Size 2136
RefSeq ORF 1392
Locus ID 9039
Domains UBACT, ThiF
Protein Pathways Ubiquitin mediated proteolysis
Gene Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) encodes the longer isoform (1).

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