C4BPB (NM_001017365) Human Untagged Clone

CAT#: SC319699

C4BPB (untagged)-Human complement component 4 binding protein, beta (C4BPB), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: C4BPB
• Synonyms: C4BP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001017365.1 ATTCCCAGAAACCAGGAAATTTCTGAAACTGAGTTTTAAACCTGGCAACTCTTTTACCAT
  CCCTTTGTATTTTTGCAGTTCCTCCCTATACCAGCTTCCTTACAGCTGTTCTGATTTCCT
  GTCGTAAGATTTTTTCTTTTCATTTTCTCCAGGGAGGGTAAATCAATATAACCTCTTCTC
  TAGAGAGGAGGTGGTTAGGTTGGTCTTAAGCAGTGTTAGAAGATCTATTTTTTTTCAAAC
  CAGGTGTCTGAGCTGGGTGAATTCCAGCCTGGGGAGAGGACTTTGATCACCAGATGTTTT
  TTTGGTGTGCGTGCTGTCTTATGGTTGCGTGGCGAGTTTCTGCTTCAGATGAGCACTGTC
  CAGAGCTTCCTCCAGTGGACAATAGCATATTTGTCGCAAAGGAGGTGGAAGGACAGATTC
  TGGGGACTTACGTTTGTATCAAGGGCTACCACCTGGTAGGAAAGAAGACCCTTTTTTGCA
  ATGCCTCTAAGGAGTGGGATAACACCACTACTGAGTGCCGCTTGGGCCACTGTCCTGATC
  CTGTGCTGGTGAATGGAGAGTTCAGTTCTTCAGGGCCTGTGAATGTAAGTGACAAAATCA
  CGTTTATGTGCAATGACCACTACATCCTCAAGGGCAGCAATCGGAGCCAGTGTCTAGAGG
  ACCACACCTGGGCACCTCCCTTTCCCATCTGCAAAAGTAGGGACTGTGACCCTCCTGGGA
  ATCCAGTTCATGGCTATTTTGAAGGAAATAACTTCACCTTAGGATCCACCATTAGTTATT
  ACTGTGAAGACAGGTACTACTTAGTGGGCGTGCAGGAGCAGCAATGCGTTGATGGGGAGT
  GGAGCAGTGCACTTCCAGTCTGCAAGTTGATCCAGGAAGCTCCCAAACCAGAGTGTGAGA
  AGGCACTTCTTGCCTTTCAGGAGAGTAAGAACCTCTGCGAAGCCATGGAGAACTTTATGC
  AACAATTAAAGGAAAGTGGCATGACAATGGAGGAGCTAAAATATTCTCTGGAGCTGAAGA
  AAGCTGAGTTGAAGGCAAAATTGTTGTAACACTACAGCTGAGCAGATGTAATAGAAATAA
  ACCTATGAATAAATTTTCTTCTTGGTTCTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001017365.1 unedited
  GTGTAGGTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGA
  TTCCCAGAAACCAGGAAATTTCTGAAACTGAGTTTTAAACCTGGCAACTCTTTTACCATC
  CCTTTGTATTTTTGCAGTTCCTCCCTATACCAGCTTCCTTACAGCTGTTCTGATTTCCTG
  TCGTAAGATTTTTTCTTTTCATTTTCTCCAGGGAGGGTAAATCAATATAACCTCTTCTCT
  AGAGAGGAGGTGGTTAGGTTGGTCTTAAGCAGTGTTAGAAGATCTATTTTTTTTCAAACC
  AGGTGTCTGAGCTGGGTGAATTCCAGCCTGGGGAGAGGACTTTGATCACCAGATGTTTTT
  TTGGTGTGCGTGCTGTCTTATGGTTGCGTGGCGAGTTTCTGCTTCAGATGAGCACTGTCC
  AGAGCTTCCTCCAGTGGACAATAGCATATTTGTCGCAAAGGAGGTGGAAGGACAGATTCT
  GGGGACTTACGTTTGTATCAAGGGCTACCACCTGGTAGGAAAGAAGACCCTTTTTTGCAA
  TGCCTCTAAGGAGTGGGATAACACCACTACTGAGTGCCGCTTGGGCCACTGTCCTGATCC
  TGTGCTGGTGAATGGAGAGTTCAGTTCTTCAGGGCCTGTGAATGTAAGTGACAAAATCAC
  GTTTATGTGCAATGACCACTACATCCTCAAGGGCAGCAATCGGAGCCAGTGTCTAGAGGA
  CCACACCTGGGCACCTCCCTTTCCCATCTGCAAAAGTAGGGACTGTGACCCTCCTGGAAT
  CCAGTTCATGGCTATTTTGAAGAATACTTCACCTTAGATCCACCATTAGTTATTACTGTG
  AAGAAAGTACTACTATGGGCGTGCAGAGCAGCATGCGTGATGGGGAGTGGAGCATGCACT
  CAGTCTGCAGTGATCAGAGCTCCAACAGAGTGTGGGAGCACTCTGCTTTCAGAAAGTAGA
  ACCTTCTGCGAGCATGGAGAACTTTATGCA
• Restriction Sites: Please inquire
• ACCN: NM_001017365
• ORF Size: 759 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001017365.1, NP_001017365.1
• RefSeq Size: 968
• RefSeq ORF: 759
• Locus ID: 725
• Protein Pathways: Complement and coagulation cascades
• Gene Summary: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3), also known as A12, differs in the 5' UTR compared to variant 1. Variants 1, 3 and 5 encode the same isoform (1).