PDCD10 (NM_145860) Human Untagged Clone

CAT#: SC319754

PDCD10 (untagged)-Human programmed cell death 10 (PDCD10), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDCD10
• Synonyms: CCM3; TFAR15
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_145860.1 GGGGGATCCGGGAGTTGAAGAGGGCTGCAAGGTGGGAAGTGAAGTCAGTGCCTCAGTTGC
  TGCTTTCTCCTCTAAATCTTGGTCTCTTGTTTGGAAGTGACTAACAGCATTTTGGCATGA
  GAAAGCCCTAAAAAGATCAGTGTGTTTTTTGTGTCCAATTCTTTTATCACCAAAAAAGAG
  AAGAAATATTGCAGTGAATGAAGATTCCTCTGCATTTTAGCACTGCTTTTTCAACTGTAG
  TTGGCTTTTGAATGAGGATGACAATGGAAGAGATGAAGAATGAAGCTGAGACCACATCCA
  TGGTTTCTATGCCCCTCTATGCAGTCATGTATCCTGTGTTTAATGAGCTAGAACGAGTAA
  ATCTGTCTGCAGCCCAGACACTGAGAGCCGCTTTCATCAAGGCTGAAAAAGAAAATCCAG
  GTCTCACACAAGACATCATTATGAAAATTTTAGAGAAAAAAAGCGTGGAAGTTAACTTCA
  CGGAGTCCCTTCTTCGTATGGCAGCTGATGATGTAGAAGAGTATATGATTGAACGACCAG
  AGCCAGAATTCCAAGACCTAAACGAAAAGGCACGAGCACTTAAACAAATTCTCAGTAAGA
  TCCCAGATGAGATCAATGACAGAGTGAGGTTTCTGCAGACAATCAAGGATATAGCTAGTG
  CAATAAAAGAACTTCTTGATACAGTGAATAATGTCTTCAAGAAATATCAATACCAGAACC
  GCAGGGCACTTGAACACCAAAAGAAAGAATTTGTAAAGTACTCCAAAAGTTTCAGTGATA
  CTCTGAAAACGTATTTTAAAGATGGCAAGGCAATAAATGTGTTCGTAAGTGCCAACCGAC
  TAATTCATCAAACCAACTTAATACTTCAGACCTTCAAAACTGTGGCCTGAAAGTTGTATA
  TGTTAAGAGATGTACTTCTCAGTGGCAGTATTGAACTGCCTTTATCTGTAAATTTTAAAG
  TTTGACTGTATAAATTATCAGTCCCTCCTGAAGGGATCTAATCCAGGATGTTGAATGGGA
  TTATTGCCATCTTACACCATATTTTTGTAAAATGTAGCTTAATCATAATCTCACACTGAA
  GATTTTGCATCACTTTTGCTATTATCATTCTTTTAAGAATTATAAGCCAAAAGAATTTAC
  GCCTTAATGTGTCATTATATAACATTCCTTAAAAGAATTGTAAATATTGGTGTTTGTTTC
  TGACATTTTAACTTGAAAGCGATATGCTGCAAGATAATGTATTTAACAATATTTGGTGGC
  AAATATTCAATAAATAGTTTACATCTGTCCAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145860.1 unedited
  CAGTAGCATTTGTATACGACTCCTATAGGGCGGCCGCTGATATTCGGCCATTACGGCCGG
  GGGATCCGGGAGTTGAAGAGGGCTGCAAGGTGGGAAGTGAAGTCAGTGCCTCAGTTGCTG
  CTTTCTCCTCTAAATCTTGGTCTCTTGTTTGGAAGTGACTAACAGCATTTTGGCATGAGA
  AAGCCCTAAAAAGATCAGTGTGTTTTTTGTGTCCAATTCTTTTATCACCAAAAAAGAGAA
  GAAATATTGCAGTGAATGAAGATTCCTCTGCATTTTAGCACTGCTTTTTCAACTGTAGTT
  GGCTTTTGAATGAGGATGACAATGGAAGAGATGAAGAATGAAGCTGAGACCACATCCATG
  GTTTCTATGCCCCTCTATGCAGTCATGTATCCTGTGTTTAATGAGCTAGAACGAGTAAAT
  CTGTCTGCAGCCCAGACACTGAGAGCCGCTTTCATCAAGGCTGAAAAAGAAAATCCAGGT
  CTCACACAAGACATCATTATGAAAATTTTAGAGAAAAAAAGCGTGGAAGTTAACTTCACG
  GAGTCCCTTCTTCGTATGGCAGCTGATGATGTAGAAGAGTATATGATTGAACGACCAGAG
  CCAGAATTCCAAGACCTAAACGAAAAGGCACGAGCACTTAAACAAATTCTCAGTAAGATC
  CCAGATGAGATCAATGACAGAGTGAGGTTTCTGCAGACAATCAAGATATAGCTAGTGCAA
  TAAAAGAACTTCTTGATACAGTGAATAATGTCTTCAAGAATATCAATACCAGACCGCAGG
  CACTTGACACCAAAGAAAGAATTTGTAAGTACTCAAAGTTTCAGTGATACTCTGAAACGT
  ATTTTAAAGATGCAGCAATAATGTTGTTCGTAGTGCACGACTAATCATCAACACTATTAC
  TCAGACTCAACTGTGCTGAGTTGTATATGTTAAGAGATGTACTCTCATGCAGTATTGACT
  GCTTATCTGTAT
• Restriction Sites: Please inquire
• ACCN: NM_145860
• ORF Size: 639 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_145860.1, NP_665859.1
• RefSeq Size: 1212
• RefSeq ORF: 639
• Locus ID: 11235
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 encode the same isoform.