HOMER3 (NM_004838) Human Untagged Clone

CAT#: SC319896

HOMER3 (untagged)-Human homer homolog 3 (Drosophila) (HOMER3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HOMER3
• Synonyms: HOMER-3; VESL3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004838.2 GCGGCGCGGAGGGCGCGGGCCCGGGAGCCAGGGAGCGAGCGGGGCGCCCGGCAGCGCGGA
  GTCAGCGCCGCGGGGGCCGCACCCGACTCGCGCCTGGACACTCGCGGGGCGCCGACCTGG
  CAGGGGGCCAAACCAGTGCTCCTGCCACCTCTCTGGCTGCCCCCTAGAGCCTGCCCATCC
  CAGCCTGACCAATGTCCACAGCCAGGGAGCAGCCAATCTTCAGCACACGGGCGCACGTGT
  TCCAAATTGACCCAGCCACCAAGCGAAACTGGATCCCAGCGGGCAAGCACGCACTCACTG
  TCTCCTATTTCTACGATGCCACCCGCAATGTGTACCGCATCATCAGCATCGGAGGCGCCA
  AGGCCATCATCAACAGCACTGTCACTCCCAACATGACCTTCACCAAAACTTCCCAGAAGT
  TCGGGCAGTGGGCCGACAGTCGCGCCAACACAGTCTACGGCTTGGGCTTTGCCTCTGAAC
  AGCATCTGACACAGTTTGCCGAGAAGTTCCAGGAAGTGAAGGAAGCAGCCAGGCTGGCCA
  GGGAGAAATCTCAGGATGGCGGGGAGCTCACCAGTCCAGCCCTGGGGCTCGCCTCCCACC
  AGGTGCCCCCGAGCCCTCTCGTCAGTGCCAACGGCCCCGGCGAGGAAAAACTGTTCCGCA
  GCCAGAGCGCTGATGCCCCCGGCCCCACAGAGCGCGAGCGGCTAAAGAAGATGTTGTCTG
  AGGGCTCCGTGGGCGAGGTACAGTGGGAGGCCGAGTTTTTCGCACTGCAGGACAGCAACA
  ACAAGCTGGCAGGCGCCCTGCGAGAGGCCAACGCCGCCGCAGCCCAGTGGAGGCAGCAGC
  TGGAGGCTCAGCGTGCAGAGGCCGAGCGGCTGCGGCAGCGGGTGGCTGAGCTGGAGGCTC
  AGGCAGCTTCAGAGGTGACCCCCACCGGTGAGAAGGAGGGGCTGGGCCAGGGCCAGTCGC
  TGGAACAGCTGGAAGCTCTGGTGCAAACCAAGGACCAGGAGATTCAGACCCTGAAGAGTC
  AGACTGGGGGGCCCCGCGAGGCCCTGGAGGCTGCCGAGCGTGAGGAGACTCAGCAGAAGG
  TGCAGGACCTGGAGACCCGCAATGCGGAGTTGGAGCACCAGCTGCGGGCGATGGAGCGCA
  GCCTGGAGGAGGCACGGGCAGAGCGGGAGCGGGCGCGGGCTGAGGTGGGCCGGGCAGCGC
  AGCTGCTGGACGTCAGGCTGTTTGAGCTGAGTGAGCTGCGTGAGGGCCTGGCCCGCCTGG
  CTGAGGCTGCGCCCTGAGCCGGGGCTGGTTTTCTATGAACGATTCCGGCCTGGGATGCGG
  GCCAGGCTGCAGGCGGCATAGTTGGGCCCATTCGTCCTGGAAAGGGACTGGGGGGTCCCA
  ACTTAGCCCTGGGTGGGCCGGGCCGGGCTGGGCTGGGGTGGGCCCCAGTCGGCTCTGGTT
  GTTGGCAGCTTTGGGGCTGTTTTTGAGCTTCTCATTGTGTAGAATTTCTAGATCCCCCGA
  TTACATTTCTAAGCGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  A
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004838.2 unedited
  AGTAGATTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCGGCGCGGA
  GGGCGCGGGCCCGGGAGCCAGGGAGCGAGCGGGGCGCCCGGCAGCGCGGAGTCAGCGCCG
  CGGGGGCCGCACCCGACTCGCGCCTGGACACTCGCGGGGCGCCGACCTGGCAGGGGGCCA
  AACCAGTGCTCCTGCCACCTCTCTGGCTGCCCCCTAGAGCCTGCCCATCCCAGCCTGACC
  AATGTCCACAGCCAGGGAGCAGCCAATCTTCAGCACACGGGCGCACGTGTTCCAAATTGA
  CCCAGCCACCAAGCGAAACTGGATCCCAGCGGGCAAGCACGCACTCACTGTCTCCTATTT
  CTACGATGCCACCCGCAATGTGTACCGCATCATCAGCATCGGAGGCGCCAAGGCCATCAT
  CAACAGCACTGTCACTCCCAACATGACCTTCACCAAAACTTCCCAGAAGTTCGGGCAGTG
  GGCCGACAGTCGCGCCAACACAGTCTACGGCTTGGGCTTTGCCTCTGAACAGCATCTGAC
  ACAGTTTGCCGAGAAGTTCCAGGAAGTGAAGGAAGCAGCCAGGCTGGCCAGGGAGAAATC
  TCAGGATGGCGGGGAGCTCACCAGTCCAGCCCTGGGGCTCGCCTCCCACCAGGTGCCCCC
  GAGCCCTCTCGTCAGTGCCAACGGCCCCGGCGAGGAAAAACTGTTCCGCAGCCAGAGCGC
  TGATGCCCCCGGCCCCACAGAGCGCGAGCGGCTAAAGAGATGTGTCTGAGGCTCCGTGGG
  GCGAGGTACAGTGGGAGGCCGGAGTTTTCGCACTGCAGACAGCACAACAGCTGCAGCGCC
  CTGCGGAGGCCAACGCCGCCGCAGCCATGAGCAGCAGCTGAGCCTCACGTGCAAGCGACG
  CTGCGCACGGTGCTGACTGAAGCTCAGCACTTCAAGTGAACCCCACGTGAAAGGAGGGTC
  CTGGCAAGCAGTCCTGGACACCTGGAACTCTTGTGGTCA
• Restriction Sites: Please inquire
• ACCN: NM_004838
• ORF Size: 1086 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_004838.2, NP_004829.2
• RefSeq Size: 1561
• RefSeq ORF: 1086
• Locus ID: 9454
• Domains: WH1
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (2), termed Homer-3A01, differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein (isoform 1).