FGFR1 Oncogene Partner (FGFR1OP) (NM_194429) Human Untagged Clone

CAT#: SC319912

FGFR1OP (untagged)-Human FGFR1 oncogene partner (FGFR1OP), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FGFR1OP
• Synonyms: FOP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_194429.1 GAGAGAGAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGG
  GACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTC
  CGAGCAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTA
  GTTAATGAGAGCCTGAGAAAGTTTTTAAATACCAAAGACGGTCGTTTAGTGGCTAGTCTT
  GTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAA
  ACTAGCACACTGCAAGGTCTCGAAGGTCGAGAGAATTTAGCCCGAGATTTAGGTATAATT
  GAAGCAGAAGGTACTGTGGGTGGACCCTTATTATTAGAAGTGATCAGGCGCTGTCAACAG
  AAAGAAAAAGGGCCAACCACTGGGGAAGGTGCACTTGATCTATCTGATGTACATTCTCCA
  CCAAAGTCACCAGAGGGAAAAACAAGTGCACAGACAACACCAAGTAAGAAGGCCAATGAT
  GAGGCCAATCAGAGTGATACAAGTGTCTCCTTGTCAGAACCCAAGAGCAAAAGCAGCCTT
  CACTTACTGTCCCATGAAACAAAAATTGGATCTTTTCTAAGCAACAGAACTTTAGATGGC
  AAAGACAAAGCTGGCCTTTGTCCAGATGAAGATGATATGGAAGGAGATTCTTTCTTTGAT
  GATCCCATTCCTAAGCCAGAGAAAACTTACGGTTTGAGGAATGAACCTAGGAAGCAAGCA
  GGAAGTCTGGCCTCGCTCTCGGATGCACCCCCCTTAAAAAGTGGACTCAGCTCCCTGGCG
  GGAGCCCCTTCTTTAAAAGACTCTGAGAGTAAAAGGGGAAATACAGTTTTGAAAGATCTG
  AAATTGATCAGTGATAAAATTGGATCACTTGGATTAGGAACTGGAGAAGATGATGACTAT
  GTTGATGATTTTAATAGTACCAGCCATCGCTCAGAGAAAAGTGAGATAAGTATTGGTGAA
  GAGATAGAAGAAGACCTTTCTGTGGAAATAGATGACATCAATACCAGTGATAAGCTTGAT
  GACCTCACACAAGATCTGACTGTATCCCAGCTCAGTGATGTTGCGGATTATCTGGAAGAT
  GTTGCATAGACACGAAGAAGGAAGTATTCTAATTAACAAGGACAGAGGACTGACCGGTTC
  CATTTTTTTTTTTTCCAGACAATCACTCAGCTGGAATGTCTGCTCTCTATTGGTGCCTTG
  CATTTCAAAAACACTGCAGATATTTTTTAAAAGTAATTTTCATTTTACTAAACAAAATAC
  TTCCTATTTGAGCCCATGTGTGGAAGATTTAATATTCTTAATTTAGCTGTACATTTCTTT
  ATGGAAATTGATTATCTACATTCAGTTTCATTACAGGGAAGGAACCCATGAAAACATCAG
  TGTTAAGAGCATGATGAAAGGTGTCAATAAAGCCGTAGGATCACGCAAAAAAAAAAAAAA
  AAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_194429.1 unedited
  TCTTATGTTGTGAAGTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGA
  GAGAGAGATGGCGGCGACGGCGGCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGA
  CCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCG
  AGCAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGT
  TAATGAGAGCCTGAGAAAGTTTTTAAATACCAAAGACGGTCGTTTAGTGGCTAGTCTTGT
  TGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAAC
  TAGCACACTGCAAGGTCTCGAAGGTCGAGAGAATTTAGCCCGAGATTTAGGTATAATTGA
  AGCAGAAGGTACTGTGGGTGGACCCTTATTATTAGAAGTGATCAGGCGCTGTCAACAGAA
  AGAAAAAGGGCCAACCACTGGGGAAGGTGCACTTGATCTATCTGATGTACATTCTCCACC
  AAAGTCACCAGAGGGAAAAACAAGTGCACAGACAACACCAAGTAAGAAGGCCAATGATGA
  GGCCAATCAGAGTGATACAAGTGTCTCCTTGTCAGAACCCAAGAGCAAAAGCAGCCTTCA
  CTTACTGTCCCATGAAACAAAAATTGGATCTTTTCTAAGCAACAGAACTTTAGATGGCAA
  AGACAAAGCTGGCCTTTGTCCAGATGAAGATGATATGGAAAGGAGATTCTTTCTTTGATG
  ATCCCATTCCTAAGCCAGAGAAACTTACGTTTGAGGAATGAACCTAGAAGCAAGCAGAAG
  TCTGCCTCGCTCTCGATGCACCCCCCTTAAAAGTGACTCAGCTCCTGCGGGAGCCCTCTT
  AAAGACTCTGAAGTAAAAGGGAATACAGTTTGAAGATCTGAAATGATCAGTGATAAAATG
  ATCACTTGATTAGACTG
• Restriction Sites: Please inquire
• ACCN: NM_194429
• ORF Size: 1140 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_194429.1, NP_919410.1
• RefSeq Size: 1842
• RefSeq ORF: 1140
• Locus ID: 11116
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (2) lacks an in-frame exon in the internal coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.