Cyclin F (CCNF) (NM_001761) Human Untagged Clone

CAT#: SC319920

CCNF (untagged)-Human cyclin F (CCNF)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCNF
• Synonyms: FBX1; FBXO1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001761.2 GCGAGCGCGGCGATGGGGAGCGGCGGCGTGGTCCACTGTAGGTGTGCCAAGTGTTTCTGT
  TATCCTACAAAGCGAAGAATAAGGAGGAGGCCCCGAAACCTGACCATCTTGAGTCTCCCC
  GAAGATGTGCTCTTTCACATCCTGAAATGGCTTTCTGTAGAGGACATCCTGGCCGTCCGA
  GCTGTACACTCCCAGCTGAAGGACCTGGTGGACAACCACGCCAGTGTGTGGGCATGTGCC
  AGCTTCCAGGAGCTGTGGCCGTCTCCAGGGAACCTGAAGCTCTTTGAAAGGGCTGCTGAA
  AAGGGGAATTTCGAAGCTGCTGTGAAGCTGGGCATAGCCTACCTCTACAATGAAGGCCTG
  TCTGTGTCTGATGAGGCCCGCGCAGAAGTGAATGGCCTGAAGGCCTCTCGCTTCTTCAGT
  CTCGCTGAGCGGCTGAATGTGGGTGCCGCACCTTTCATCTGGCTCTTCATCCGCCCTCCG
  TGGTCGGTGAGCGGAAGCTGCTGCAAGGCCGTGGTTCACGAGAGCCTCAGGGCAGAGTGC
  CAGCTGCAGAGGACTCACAAAGCATCCATATTGCACTGCTTGGGCAGAGTGCTGAGTCTG
  TTCGAGGATGAGGAGAAGCAGCAGCAGGCCCATGACCTGTTTGAGGAGGCTGCTCATCAG
  GGATGTCTGACCAGCTCCTACCTCCTCTGGGAAAGCGACAGGAGGACAGATGTGTCAGAT
  CCTGGGCGATGCCTCCACAGCTTCCGAAAACTCAGGGACTACGCTGCCAAAGGCTGCTGG
  GAAGCGCAGCTGTCTTTAGCCAAAGCCTGTGCAAATGCAAACCAGCTTGGACTGGAGGTG
  AGAGCTTCCAGTGAGATCGTCTGCCAGCTATTTCAGGCTTCCCAGGCTGTCAGTAAACAA
  CAAGTCTTCTCCGTGCAGAAGGGACTCAATGACACAATGAGGTACATTCTGATCGACTGG
  CTGGTGGAAGTTGCCACCATGAAGGACTTCACAAGCCTGTGCCTGCACCTGACCGTGGAG
  TGTGTGGACCGGTACCTGCGGAGGAGGCTGGTGCCGCGGTACAGGCTCCAGCTGCTGGGC
  ATCGCCTGCATGGTCATCTGCACCCGGTTTATCAGTAAAGAGATCCTGACCATCCGGGAG
  GCCGTATGGCTCACGGACAACACTTACAAGTACGAGGACCTGGTGAGAATGATGGGCGAG
  ATCGTCTCCGCCTTGGAAGGGAAGATTCGAGTCCCCACTGTGGTGGATTACAAGGAGGTC
  CTGCTGACGCTAGTCCCTGTGGAGCTGAGAACCCAGCACCTGTGCAGCTTCCTCTGCGAG
  CTCTCCCTGCTGCACACCAGCCTGTCCGCCTACGCCCCAGCCCGCCTGGCTGCCGCAGCC
  CTGCTCCTGGCCAGACTGACGCACGGGCAGACACAGCCCTGGACCACTCAGCTGTGGGAC
  CTCACCGGATTCTCCTATGAAGACCTCATTCCCTGCGTCTTGAGCCTCCATAAGAAGTGC
  TTCCATGATGACGCCCCCAAGGACTACAGGCAAGTCTCTCTGACCGCCGTGAAGCAGCGG
  TTTGAGGACAAGCGCTATGGAGAAATCAGCCAGGAAGAGGTGCTGAGCTACAGCCAGTTG
  TGTGCTGCATTAGGAGTGACACAAGACAGCCCCGACCCCCCGACTTTCCTCAGCACAGGG
  GAGATCCACGCCTTCCTCAGCTCTCCCTCGGGGCGGAGAACCAAACGGAAGCGGGAGAAC
  AGCCTCCAGGAAGACAGAGGCAGCTTCGTTACCACCCCCACTGCGGAGCTGTCCAGCCAG
  GAGGAGACGCTGCTGGGCAGCTTCCTCGACTGGAGCCTGGACTGCTGCTCTGGCTATGAA
  GGCGACCAGGAGAGTGAGGGCGAGAAGGAGGGCGACGTGACAGCTCCCAGCGGCATCCTC
  GATGTCACCGTGGTCTACCTGAACCCAGAACAGCATTGCTGCCAGGAATCCAGTGATGAG
  GAGGCTTGTCCAGAGGACAAGGGACCCCAGGACCCACAGGCACTGGCGCTGGACACCCAG
  ATCCCTGCAACCCCTGGACCCAAACCCCTGGTCCGCACCAGCCGGGAGCCAGGGAAGGAC
  GTCACGACCTCAGGGTACTCCTCCGTCAGCACCGCAAGTCCCACAAGCTCCGTGGACGGT
  GGCTTGGGGGCCCTGCCCCAACCTACCTCAGTGCTGTCCCTGGACAGTGACTCGCACACA
  CAGCCCTGCCACCATCAGGCCAGGAAGTCATGTTTACAGTGTCGTCCCCCAAGTCCCCCG
  GAGAGCAGTGTTCCCCAGCAACAGGTGAAGCGGATAAACCTATGCATACACAGTGAGGAG
  GAGGACATGAACCTGGGCCTTGTGAGGCTGTAAGTGTGTCAGCACATTTGCCGCAGTGGA
  TGTGTACTGAGGGGGCTGGAGGCGAAGGGTGGGAGCATAGCATAGGAACGCTGCATAGAC
  CATGGAGGCCTTTGCGCAGAGAGCAGAGAGGATGACTTGCGGCCACCAAGTTTCTGTCTC
  CGCGGGAGTCCCGTGCAAGCCATCAGAATGTTGAAATGAGGGTGAAGAGCTCAGATCCCT
  CTCTTTGGAAAGTTTAGCCTGGAAGCAGTTGGCCACACTGTGTGGAGGGCACCTCTCTGT
  CCCTTCCGTGTCTCACTGTCTCTGGAAGCTTCAGCCCATGTGTGTCCTGGTGTTCCCAGC
  CCCACCAGAGCCCCGTGCCGGGAGCTGACAGCTTTCACGCTTAAGGCACGTGTGACCTGG
  GTAGTCAGACACCACTTGAGCCCCTGCCCACATCTGCTGGTTTGGGGCTTCAGTGGGGAG
  CTGACAGCTGTGAGCACACCACTGTCCCCTCATCCACCTCGGCCTGCATGGGGCACCCAC
  TTCCTTCTGGGTGGGGCTTCCATGGTAAGGGGGCCTGCGTCCCTGCACACTGCGAGGACT
  GCCTTGGCCACAGGCCCACTCCCTACGACACGTGACTCGTTTTAGAGCTCTGTCCCAGAG
  GCGTTCGTATGTGACCCACAGATGGCGTCAATGTGAACACCTCTCTTTGTGCTGAATTTC
  TGGGCCATTCTTTTCCTGTCTTATTTCTAAATTTCCTTCTTCCAAGATGAAAACAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001761.2 unedited
  GTCGGATGTGTCATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCGA
  GCGCGGCGATGGGGAGCGGCGGCGTGGTCCACTGTAGGTGTGCCAAGTGTTTCTGTTATC
  CTACAAAGCGAAGAATAAGGAGGAGGCCCCGAAACCTGACCATCTTGAGTCTCCCCGAAG
  ATGTGCTCTTTCACATCCTGAAATGGCTTTCTGTAGAGGACATCCTGGCCGTCCGAGCTG
  TACACTCCCAGCTGAAGGACCTGGTGGACAACCACGCCAGTGTGTGGGCATGTGCCAGCT
  TCCAGGAGCTGTGGCCGTCTCCAGGGAACCTGAAGCTCTTTGAAAGGGCTGCTGAAAAGG
  GGAATTTCGAAGCTGCTGTGAAGCTGGGCATAGCCTACCTCTACAATGAAGGCCTGTCTG
  TGTCTGATGAGGCCCGCGCAGAAGTGAATGGCCTGAAGGCCTCTCGCTTCTTCAGTCTCG
  CTGAGCGGCTGAATGTGGGTGCCGCACCTTTCATCTGGCTCTTCATCCGCCCTCCGTGGT
  CGGTGAGCGGAAGCTGCTGCAAGGCCGTGGTTCACGAGAGCCTCAGGGCAGAGTGCCAGC
  TGCAGAGGACTCACAAAGCATCCATATTGCACTGCTTGGGCAGAGTGCTGAGTCTGTTCG
  AGGATGAGAGAAGCAGCAGCAGCCCATGACCTGTTTGAGGAGGCTGCTCATCAGGGATGT
  CTGACCAGCTCCTACCTCCTCTGGGAAAGCGACAGGAGACAGATGTGTCAGATCCTGGCG
  ATGCCTCCACAGCTTCCGAAACTCAGGACTACGCTGCCAAAGCTGCTGGGAAGCGCAGCT
  GTCTTTAGCCAAGCCTGTGCAATGCAACCAGCTTGACTGGAGGTGGAAAGCTCAGTGAGA
  ATCGTCTGCAGCTATTCAGGCTCCAAGCTGTCAGTAAACAACAGTCCTCTCGGCAAAGAC
  TCAATGAACCATGAGTAATTCTATCGACTGGCTGGTGGAGTGGCCACCACTG
• Restriction Sites: Please inquire
• ACCN: NM_001761
• ORF Size: 2361 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001761.2, NP_001752.2
• RefSeq Size: 4287
• RefSeq ORF: 2361
• Locus ID: 899
• Domains: F-box, cyclin_C, CYCLIN, cyclin
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]