TAX1BP3 (NM_014604) Human Untagged Clone

CAT#: SC319925

TAX1BP3 (untagged)-Human Tax1 (Human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1


  "NM_014604" in other vectors (6)

Reconstitution Protocol

USD 420.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TAX1BP3
Synonyms TIP-1; TIP1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_014604.2 GGGGACTCTGCTGCCGGCTTCTCGGAGCGGCGCTGGGCGACCAGAGCAGGGTCGAGATGT
CCTACATCCCGGGCCAGCCGGTCACCGCCGTGGTGCAAAGAGTTGAAATTCACAAGCTGC
GTCAAGGTGAGAACTTAATCCTGGGTTTCAGCATTGGAGGTGGAATCGACCAGGACCCTT
CCCAGAATCCCTTCTCTGAAGACAAGACGGACAAGGGTATTTATGTCACACGGGTGTCTG
AAGGAGGCCCTGCTGAAATCGCTGGGCTGCAGATTGGAGACAAGATCATGCAGGTGAACG
GCTGGGACATGACCATGGTCACACACGACCAGGCCCGCAAGCGGCTCACCAAGCGCTCGG
AGGAGGTGGTGCGTCTGCTGGTGACGCGGCAGTCGCTGCAGAAGGCCGTGCAGCAGTCCA
TGCTGTCCTAGCAGCCACCACCATCTGCGACTCCTGCCTGCCGCCTCTCTGTACAGTAAC
GCCACTTCCACACTCTGTCCCCATCTGGCTTCTGCTGACCGCTGGGCCCCAGCTCAGAAG
GGCTATAGCTGGTCCCAGAGGCCTGGCCTGGCCTTCCTTCCCTTCTCCCATCCCTGGCCT
GGGGCCTCTGGGACCAGCTTTCTCTCCTGGACACCGAGGATTGGAAATAAGGGCCTGGAG
CTGAGTAGTAGCCAGTCTGCTGTGACCACAGGCTCAGGTCCGACCCTGCTGCTTGGCCAC
AGCAGTGGCTGGGCAAGTGGGAACCACTATCTCTTGGGAGCCCCCAAAAGCTGGGAAATG
CTGGAGGAACCAGGCCTTTCCCGCTTTTGCCTGGCTGCAGGGTTCGGCTCCGCCCCTGCC
CCCCAGCCCTCGTGTGTCCACATCGCAGTGCCTCTGCCCCTCGGGGGACTGGACACACAT
CCTGCCAGAGGCGCTACGAAGCTTTGCCCAGATGAAGCCAGGTGGGCTCCGCGTTCACTC
CCACTCTCCCGAGGGGTGCTGGCCTCCCCAGGGTTTGCCTTCTTACGGATTTAGACGAGG
TTCGAGGCTCACCTATCAGGGCAGCTCTCAGGATTGTCATTTTCCTCTTTGCCTGTGGGT
TTAACTTTTGTATTTTTTTAATCACAAGTTTGATACAAAATGTTTTTATCGTACTCTTTG
GAGATGCCCATTCTACTTTTGAATTTAGCTTTTACTAATTCGCATCTGGAAGCTCAGCAA
GTGCACAAGCCTTACTTTGGTTACCGTGGAAACCACTGCCGCCCCTCCCCGATGTGGTGC
GCTCAATAAAAATGCTGGAATGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_014604.2 unedited
GCGTAGGTTTGTATACGACTCCTATAGGGCGGCCGGGTAATTCGGCCATTATGGCCGGGG
ACTCTGCTGCCGGCTTCTCGGAGCGGCGCTGGGCGACCAGAGCAGGGTCGAGATGTCCTA
CATCCCGGGCCAGCCGGTCACCGCCGTGGTGCAAAGAGTTGAAATTCACAAGCTGCGTCA
AGGTGAGAACTTAATCCTGGGTTTCAGCATTGGAGGTGGAATCGACCAGGACCCTTCCCA
GAATCCCTTCTCTGAAGACAAGACGGACAAGGGTATTTATGTCACACGGGTGTCTGAAGG
AGGCCCTGCTGAAATCGCTGGGCTGCAGATTGGAGACAAGATCATGCAGGTGAACGGCTG
GGACATGACCATGGTCACACACGACCAGGCCCGCAAGCGGCTCACCAAGCGCTCGGAGGA
GGTGGTGCGTCTGCTGGTGACGCGGCAGTCGCTGCAGAAGGCCGTGCAGCAGTCCATGCT
GTCCTAGCAGCCACCACCATCTGCGACTCCTGCCTGCCGCCTCTCTGTACAGTAACGCCA
CTTCCACACTCTGTCCCCATCTGGCTTCTGCTGACCGCTGGGCCCCAGCTCAGAAGGGCA
TTTAGCTGGGTACTATGATGTCTTGCCTGGCCCTTCCTTCCCTTTCTCCCATCCCCTGCC
CTGGGGCCTCTGGGACCCAGGCTTTTCTCTCTGGACACCGAGGAATTGGAAATAAGGGCC
CTGAACTGAGTAGTAACCTGTCTGCTGTGACCAAAGGCTCAGGTCGACCCTGCTGCTTGG
CCACCGCAGTGCTGGGCAAGTGGAAACACTATCTCTGGGAGCCCCCAAAGCTGGAAATGC
CTGGAGTACCAGCTTTCCGATTTAGCTGCTGCAGGTTCGGCTCGACCCTGCACCTACCTC
GTGGGTCACATCG
Restriction Sites Please inquire     
ACCN NM_014604
ORF Size 375 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_014604.2, NP_055419.1
RefSeq Size 1421
RefSeq ORF 375
Locus ID 30851
Domains PDZ
Gene Summary This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

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