TAX1BP3 (NM_014604) Human Untagged Clone

CAT#: SC319925

TAX1BP3 (untagged)-Human Tax1 (Human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TAX1BP3
• Synonyms: TIP-1; TIP1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014604.2 GGGGACTCTGCTGCCGGCTTCTCGGAGCGGCGCTGGGCGACCAGAGCAGGGTCGAGATGT
  CCTACATCCCGGGCCAGCCGGTCACCGCCGTGGTGCAAAGAGTTGAAATTCACAAGCTGC
  GTCAAGGTGAGAACTTAATCCTGGGTTTCAGCATTGGAGGTGGAATCGACCAGGACCCTT
  CCCAGAATCCCTTCTCTGAAGACAAGACGGACAAGGGTATTTATGTCACACGGGTGTCTG
  AAGGAGGCCCTGCTGAAATCGCTGGGCTGCAGATTGGAGACAAGATCATGCAGGTGAACG
  GCTGGGACATGACCATGGTCACACACGACCAGGCCCGCAAGCGGCTCACCAAGCGCTCGG
  AGGAGGTGGTGCGTCTGCTGGTGACGCGGCAGTCGCTGCAGAAGGCCGTGCAGCAGTCCA
  TGCTGTCCTAGCAGCCACCACCATCTGCGACTCCTGCCTGCCGCCTCTCTGTACAGTAAC
  GCCACTTCCACACTCTGTCCCCATCTGGCTTCTGCTGACCGCTGGGCCCCAGCTCAGAAG
  GGCTATAGCTGGTCCCAGAGGCCTGGCCTGGCCTTCCTTCCCTTCTCCCATCCCTGGCCT
  GGGGCCTCTGGGACCAGCTTTCTCTCCTGGACACCGAGGATTGGAAATAAGGGCCTGGAG
  CTGAGTAGTAGCCAGTCTGCTGTGACCACAGGCTCAGGTCCGACCCTGCTGCTTGGCCAC
  AGCAGTGGCTGGGCAAGTGGGAACCACTATCTCTTGGGAGCCCCCAAAAGCTGGGAAATG
  CTGGAGGAACCAGGCCTTTCCCGCTTTTGCCTGGCTGCAGGGTTCGGCTCCGCCCCTGCC
  CCCCAGCCCTCGTGTGTCCACATCGCAGTGCCTCTGCCCCTCGGGGGACTGGACACACAT
  CCTGCCAGAGGCGCTACGAAGCTTTGCCCAGATGAAGCCAGGTGGGCTCCGCGTTCACTC
  CCACTCTCCCGAGGGGTGCTGGCCTCCCCAGGGTTTGCCTTCTTACGGATTTAGACGAGG
  TTCGAGGCTCACCTATCAGGGCAGCTCTCAGGATTGTCATTTTCCTCTTTGCCTGTGGGT
  TTAACTTTTGTATTTTTTTAATCACAAGTTTGATACAAAATGTTTTTATCGTACTCTTTG
  GAGATGCCCATTCTACTTTTGAATTTAGCTTTTACTAATTCGCATCTGGAAGCTCAGCAA
  GTGCACAAGCCTTACTTTGGTTACCGTGGAAACCACTGCCGCCCCTCCCCGATGTGGTGC
  GCTCAATAAAAATGCTGGAATGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014604.2 unedited
  GCGTAGGTTTGTATACGACTCCTATAGGGCGGCCGGGTAATTCGGCCATTATGGCCGGGG
  ACTCTGCTGCCGGCTTCTCGGAGCGGCGCTGGGCGACCAGAGCAGGGTCGAGATGTCCTA
  CATCCCGGGCCAGCCGGTCACCGCCGTGGTGCAAAGAGTTGAAATTCACAAGCTGCGTCA
  AGGTGAGAACTTAATCCTGGGTTTCAGCATTGGAGGTGGAATCGACCAGGACCCTTCCCA
  GAATCCCTTCTCTGAAGACAAGACGGACAAGGGTATTTATGTCACACGGGTGTCTGAAGG
  AGGCCCTGCTGAAATCGCTGGGCTGCAGATTGGAGACAAGATCATGCAGGTGAACGGCTG
  GGACATGACCATGGTCACACACGACCAGGCCCGCAAGCGGCTCACCAAGCGCTCGGAGGA
  GGTGGTGCGTCTGCTGGTGACGCGGCAGTCGCTGCAGAAGGCCGTGCAGCAGTCCATGCT
  GTCCTAGCAGCCACCACCATCTGCGACTCCTGCCTGCCGCCTCTCTGTACAGTAACGCCA
  CTTCCACACTCTGTCCCCATCTGGCTTCTGCTGACCGCTGGGCCCCAGCTCAGAAGGGCA
  TTTAGCTGGGTACTATGATGTCTTGCCTGGCCCTTCCTTCCCTTTCTCCCATCCCCTGCC
  CTGGGGCCTCTGGGACCCAGGCTTTTCTCTCTGGACACCGAGGAATTGGAAATAAGGGCC
  CTGAACTGAGTAGTAACCTGTCTGCTGTGACCAAAGGCTCAGGTCGACCCTGCTGCTTGG
  CCACCGCAGTGCTGGGCAAGTGGAAACACTATCTCTGGGAGCCCCCAAAGCTGGAAATGC
  CTGGAGTACCAGCTTTCCGATTTAGCTGCTGCAGGTTCGGCTCGACCCTGCACCTACCTC
  GTGGGTCACATCG
• Restriction Sites: Please inquire
• ACCN: NM_014604
• ORF Size: 375 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014604.2, NP_055419.1
• RefSeq Size: 1421
• RefSeq ORF: 375
• Locus ID: 30851
• Domains: PDZ
• Gene Summary: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).