FBXO44 (NM_183412) Human Untagged Clone

CAT#: SC320134

FBXO44 (untagged)-Human F-box protein 44 (FBXO44), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO44
• Synonyms: FBG3; FBX6A; FBX30; Fbx44; Fbxo6a
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_183412.2 GCTTGGGCGGCCCAGCGGATCGTGCCGCGGCGGCCGAGCGCAGCTACAGGAGGGTGTCCA
  GAAGCCACAAGCCATGGCTGTGGGGAACATCAACGAGCTGCCCGAGAACATCCTGCTGGA
  GCTGTTCACGCACGTGCCCGCCCGCCAGCTGCTGCTGAACTGCCGCCTGGTCTGCAGCCT
  CTGGCGGGACCTCATCGACCTCGTGACCCTCTGGAAACGCAAGTGCCTGCGAGAGGGCTT
  CATCACTGAGGACTGGGACCAGCCCGTGGCCGACTGGAAGATCTTCTACTTCTTACGGAG
  CCTGCACAGGAACCTCCTGCACAACCCGTGCGCTGAAGAGGGGTTCGAGTTCTGGAGCCT
  GGATGTGAATGGAGGCGATGAGTGGAAGGTGGAGGATCTCTCTCGAGACCAGAGGAAGGA
  ATTCCCCAATGACCAGGTTCGCAGCCAGGCCAGATTGCGGGTCCAAGTACCAGCTGTGCG
  TTCAGCTCCTGTCGTCCGCGCACGCGCCTCTGGGGACCTTCCAGCCAGACCCGGCGACCA
  TCCAGCAGAAGAGCGATGCCAAGTGGAGGGAGGTCTCCCACACATTCTCCAACTACCCGC
  CCGGCGTCCGCTACATCTGGTTTCAGCACGGCGGCGTGGACACTCATTACTGGGCCGGCT
  GGTACGGCCCGAGGGTCACCAACAGCAGCATCACCATCGGGCCCCCGCTGCCCTGACACC
  CCCTGAGCCCCCATCTGCTGAACCCTGACTGGTAAACAACTGCTGTCAGAAAAGGGCTGG
  GCTTGGGAAGGGGAGGTGGAGGCCAGGTGTCCCCAGACCTCTAACCCTTGCCCCTAGCAG
  CCTCTTCTTTGTGGAGCCTCTCAGTGTGGGCAGCCCTCGCATGCTGGGGTCGGGCCAGCT
  CTCCCCGAAAGGTCTTGACCTGAATGATGGCCGGGGAAGCCTGCGTGTGCCCCTTTCAGA
  GACGGAGCACCTGAGATGTGGGAGGTGCAGCATGTTCCCCTGGGCCCCTCAGAAAGTCGA
  GCTTGGAGGCCAGCCTGGATCTGTCTCTCCCTTCCCCTCCTGGGACCATTCTACCTGTGT
  TCTTTGACCCTCGGAGCAGGGACAGGCAAGACAACTGGCAAGCTTGCAGCTGCCCTGATG
  GTGCAGGTGCAGGGAGGTGACCATGTAACTCTGACCAATCTGGGAAGTGGAGGGTGGGCT
  CATGGGCCGTGCCCTGCCCCTGTCTGCTGCTCCCAGTCTTTCGCTCTGCCTGCCTGCTCA
  GAAGAGGTGGCTTTGGCCCAGAGGCTCAGGCCGGGACTGAGATGGACAGACCCAGGGTGG
  GGTGGGGTCCAGGTCGGGTGTGGACTGTCCTCACTGTCAGTGGAGCCCCAGAAGCTAGAT
  GGGTACCAGGTGGGGTTAGGTTCCCAGAGGACTGAGGGAATCCTGTACAGGATGTCCCAG
  GGTAGATGGGGAGCAGGATTGGGACCTGCTCTGACAGCTGGACACATGAGCCCTGGATGA
  GTATGGTAGGGGGTTTGAAGAATCCCCTGTCCACCTCCCAAATCCAGGCCCGGCCCCCTC
  TGGCTTGGAGAGCATTCCAAGCCCCCACCCCACCCCTAGAACTGCCATTCCCAAGACCTC
  TGTCTCCCAGCCAACCACCCTTGGAACTTGCCTCTTGTCCTGCTGGAAAGATAGCAGTGT
  TCTCCTGACTTCGCCCTACTGCATGCAGCCAAATAAAAGGTGTGCCCAGTCTAAAAAAAA
  AAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_183412.2 unedited
  GGCAGATTGTAGACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCG
  AGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACC
  GACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAA
  AACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCA
  CGAGGGCTTGGGCGGCCCAGCGGATCGTGCCGCGGCGGCCGAGCGCAGCTACAGGAGGGT
  GTCCAGAAGCCACAAGCCATGGCTGTGGGGAACATCAACGAGCTGCCCGAGAACATCCTG
  CTGGAGCTGTTCACGCACGTGCCCGCCCGCCAGCTGCTGCTGAACTGCCGCCTGGTCTGC
  AGCCTCTGGCGGGACCTCATCGACCTCGTGACCCTCTGGAAACGCAAGTGCCTGCGAGAG
  GGCTTCATCACTGAGGACTGGGACCAGCCCGTGGCCGACTGGAAGATCTTCTACTTCTTA
  CGGAGCCTGCACAGGAACCTCCTGCACAACCCGTGCGCTGAAGAGGGGTTCGAGTTCTGG
  AGCCTGGATGTGAATGGAGGCGATGAGTGGAAGGTGGAGGATCTCTCTCGAGACCAGAGG
  AAGGAATTCCCCAATGACCAGGTTCGCAGCCAGGCCAGATTGCGGGTCCAAGTACCAGCT
  GTGCGTTCAGCTCCTGTCGTCCGCGCACGCGCCTCTGGGGACCTTCCAGCCAGACCCGGC
  GACCATCCAGCAGAGAGCGATGCCAAGTGGAGGGAGTCTCCACAACATTCTCACTACCCG
  CCCGCGTCCGCTACATCTGTTTCAGCACGCGCGTGACACTCATTACTGGGCCGCTGGTAC
  GCCGAGGTCACAACAGCAGCATCACATCGGGCCCCCGCTGCCCTGACACCCCCCTGGATC
  TGT
• Restriction Sites: Please inquire
• ACCN: NM_183412
• ORF Size: 675 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_183412.2, NP_904319.1
• RefSeq Size: 2934
• RefSeq ORF: 675
• Locus ID: 93611
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Several alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Feb 2015]
  Transcript Variant: This variant (2) differs in the 5' UTR, uses an alternate splice junction at the 3' end of an internal exon, and lacks an alternate internal exon compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Variants 2, 3, and 5 all encode the same isoform (2).