GMPR1 (GMPR) (NM_006877) Human Untagged Clone

CAT#: SC320142

GMPR (untagged)-Human guanosine monophosphate reductase (GMPR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GMPR
• Synonyms: GMPR 1; GMPR1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006877.2 CCGGCCCACGCCAGCTCCCGGCCGCGGCACAGCAGCCCCGGCGCTCCCCGCGCCGCCCCG
  CGCAGGCGCCCCCGCCCCGCCGTCGCCGCCGCCGCAGCCAGGAGCCGCTGCACCATGCCC
  CGCATAGATGCGGACCTCAAGCTCGACTTCAAGGATGTCCTGCTCCGACCTAAGCGGAGC
  AGCCTCAAGAGCCGAGCCGAGGTGGATCTTGAACGCACCTTCACGTTTCGAAATTCAAAG
  CAGACCTACTCAGGGATTCCCATCATCGTGGCCAACATGGACACTGTGGGCACGTTTGAG
  ATGGCAGCCGTGATGTCACAGCACTCCATGTTTACAGCAATTCATAAGCATTACTCCCTG
  GATGACTGGAAGCTCTTTGCCACAAATCACCCAGAATGCCTGCAGAATGTAGCCGTGAGT
  TCAGGCAGTGGGCAGAATGATCTGGAAAAGATGACCAGCATCCTGGAAGCTGTGCCACAG
  GTTAAGTTTATTTGCCTGGATGTGGCCAATGGGTATTCAGAACATTTTGTGGAATTCGTG
  AAACTTGTCCGTGCCAAATTTCCTGAACACACCATTATGGCAGGGAACGTGGTGACAGGA
  GAAATGGTAGAAGAGCTTATTCTTTCCGGAGCAGATATCATCAAAGTGGGAGTTGGACCA
  GGTTCTGTGTGCACCACCCGCACCAAGACGGGAGTGGGGTACCCCCAGCTGAGTGCCGTC
  ATTGAGTGTGCCGACTCTGCCCATGGCCTGAAGGGCCACATCATCTCTGATGGAGGCTGT
  ACGTGTCCAGGGGATGTCGCCAAAGCCTTTGGAGCTGGAGCAGATTTTGTCATGCTGGGA
  GGAATGTTTTCGGGTCATACGGAGTGTGCTGGAGAAGTGATTGAGAGGAACGGACGGAAG
  CTCAAGCTCTTCTACGGGATGAGCTCTGACACCGCCATGAACAAGCACGCAGGAGGAGTT
  GCTGAGTACAGAGCCTCTGAGGGTAAGACTGTGGAAGTTCCTTACAAAGGAGATGTGGAA
  AACACTATCCTGGATATTCTCGGGGGACTGAGGTCCACGTGCACCTACGTGGGGGCCGCC
  AAACTCAAGGAGCTCAGCAGGAGGGCAACATTCATCCGGGTGACCCAGCAGCACAACACC
  GTGTTCAGCTAACCCTGGGGACAAAGCAGCGTCTGGCTCGAGTGGAAGCGTCCAAACCTG
  CTTTTCCCATCTCCCCCCAAGTCTGTTCCGTCAGAGCTTCTGGCTGCTCCTGAATGGTGG
  AATGCTGTGTCCTCTCTTCTGTCTCCTGCCGCCTGGAGGCTTCGGGGCTCTCCCGCCTGC
  CTTGTCGGGGCCCAGACGCAAGGCACCGATTGGGCCAACATCAGAGCCCTGCTGCCCAGA
  ACTCATAACCTCATTGTTCAAACCAACACTTGCACCTTTCTCTTTTTCTCTTTCTCTCTC
  CCTTTCTTTGTTTTTCTTTCTTTTTTAAAAGAAGATGGTTTCACTTTAATATAATGCTAT
  TATCTTAAGACTTAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_006877
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006877.2, NP_006868.2
• RefSeq Size: 1531 bp
• RefSeq ORF: 1038 bp
• Locus ID: 2766
• Cytogenetics: 6p22.3
• Domains: IMPDH
• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism
• Gene Summary: 'This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]'