B4GALT3 (NM_003779) Human Untagged Clone

CAT#: SC320166

B4GALT3 (untagged)-Human UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 (B4GALT3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: B4GALT3
• Synonyms: beta4Gal-T3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003779.2 ATGGCGGCAGCGATGCCTGCCCGGCTGTTGGGGTGGCGGTGACGACAGGCAGCAAAAGAC
  CAGCTGGTCCCAGATTCGCTGCTGGAGTGCTGGATGGAGCCTTTCTCTGCCCTCTGTGAC
  ATTTCCAATTTTAGATAATGCCTCACATCTCTGTCCCCCCGGGACCCCCTGGAGCCCCCA
  TGATCCCTAAGAAGACAGCTTGAACCTAGATCTCACCCCCAGGATGTTGCGGAGGCTGCT
  GGAGCGGCCTTGCACGCTGGCCCTGCTTGTGGGCTCCCAGCTGGCTGTCATGATGTACCT
  GTCACTGGGGGGCTTCCGAAGTCTCAGTGCCCTATTTGGCCGAGATCAGGGACCGACATT
  TGACTATTCTCACCCTCGTGATGTCTACAGTAACCTCAGTCACCTGCCTGGGGCCCCAGG
  GGGTCCTCCAGCTCCTCAAGGTCTGCCCTACTGTCCAGAACGATCTCCTCTCTTAGTGGG
  TCCTGTGTCGGTGTCCTTTAGCCCAGTGCCATCACTGGCAGAGATTGTGGAGCGGAATCC
  CCGGGTAGAACCAGGGGGCCGGTACCGCCCTGCAGGTTGTGAGCCCCGCTCCCGAACAGC
  CATCATTGTGCCTCATCGTGCCCGGGAGCACCACCTGCGCCTGCTGCTCTACCACCTGCA
  CCCCTTCTTGCAGCGCCAGCAGCTTGCTTATGGCATCTATGTCATCCACCAGGCTGGAAA
  TGGAACATTTAACAGGGCAAAACTGTTGAACGTTGGGGTGCGAGAGGCCCTGCGTGATGA
  AGAGTGGGACTGCCTGTTCTTGCACGATGTGGACCTCTTGCCAGAAAATGACCACAATCT
  GTATGTGTGTGACCCCCGGGGACCCCGCCATGTTGCCGTTGCTATGAACAAGTTTGGATA
  CAGCCTCCCGTACCCCCAGTACTTCGGAGGAGTCTCAGCACTTACTCCTGACCAGTACCT
  GAAGATGAATGGCTTCCCCAATGAATACTGGGGCTGGGGTGGTGAGGATGACGACATTGC
  TACCAGGGTGCGCCTGGCTGGGATGAAGATCTCTCGGCCCCCCACATCTGTAGGACACTA
  TAAGATGGTGAAGCACCGAGGAGATAAGGGCAATGAGGAAAATCCCCACAGATTTGACCT
  CCTGGTCCGTACCCAGAATTCCTGGACGCAAGATGGGATGAACTCACTGACATACCAGTT
  GCTGGCTCGAGAGCTGGGGCCTCTTTATACCAACATCACAGCAGACATTGGGACTGACCC
  TCGGGGTCCTCGGGCTCCTTCTGGGCCACGTTACCCACCTGGTTCCTCCCAAGCCTTCCG
  TCAAGAGATGCTGCAACGCCGGCCCCCAGCCAGGCCTGGGCCTCTATCTACTGCCAACCA
  CACAGCCCTCCGAGGTTCACACTGACTCCTCCTTCCTGTCTACCTTAATCATGAAACCGA
  ATTCATGGGGTTGTATTCTCCCCACCCTCAGCTCCTCACTGTTCTCAGAGGGATGTGAGG
  GAACTGAACTCTGGTGCCGTGCTAGGGGGTAGGGGCCTCTCCCTCACTGCTGGACTGGAG
  CTGGGCTCCTGTAGACCTGAGGGGTCCCTCTCTCTAGGGTCTCCTGTAGGGCTTATGACT
  GTGAATCCTTGATGTCATGATTTTATGTGACGATTCCTAGGAGTCCCTGCCCCTAGAGTA
  GGAGCAGGGCTGGACCCCAAGCCCCTCCCTCTTCCATGGAGAGAAGAGTGATCTGGCTTC
  TCCTCGGACCTCTGTGAATATTTATTCTATTTATGGTTCCCGGGAAGTTGTTTGGTGAAG
  GAAGCCCCTCCCTGGGCATTTTCTGCCTATGCTGGAATAGCTCCCTCTTCTGGTCCTGGC
  TCAGGGGGCTGGGATTTTGATATATTTTCTAATAAAGGACTTTGTCTCGCAAAAAAAAAA
  AAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003779.2 unedited
  GGACGATTGTATACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCG
  AGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACC
  GACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAA
  AACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCA
  CGAGGATGGCGGCAGCGATGCCTGCCCGGCTGTTGGGGTGGCGGTGACGACAGGCAGCAA
  AAGACCAGCTGGTCCCAGATTCGCTGCTGGAGTGCTGGATGGAGCCTTTCTCTGCCCTCT
  GTGACATTTCCAATTTTAGATAATGCCTCACATCTCTGTCCCCCCGGGACCCCCTGGAGC
  CCCCATGATCCCTAAGAAGACAGCTTGAACCTAGATCTCACCCCCAGGATGTTGCGGAGG
  CTGCTGGAGCGGCCTTGCACGCTGGCCCTGCTTGTGGGCTCCCAGCTGGCTGTCATGATG
  TACCTGTCACTGGGGGGCTTCCGAAGTCTCAGTGCCCTATTTGGCCGAGATCAGGGACCG
  ACATTTGACTATTCTCACCCTCGTGATGTCTACAGTAACCTCAGTCACCTGCCTGGGGCC
  CCAGGGGGTCCTCCAGCTCCTCAAGGTCTGCCCTACTGTCCAGAACGATCTCCTCTCTTA
  GTGGGTCCTGTGTCGGTGTCCTTTAGCCCAGTGCCATCACTGGCAGAGATTGTGGAGCGG
  AATCCCCGGGTAGACCAGGGGCCCGGTACCGCCTGCAGTTGTGAGCCCCGCTCCGACAGC
  CATCATTGTGCCTCATCGTGCCCGGAGCACACTGCGCTGCTGCTCTACCACTGCACCATC
  TGCAAGGCAGCAGCTGCTTATGCATTCTATGTCATCCACCAGCTGGAATGGAACATTAAC
  AGGCCGA
• Restriction Sites: Please inquire
• ACCN: NM_003779
• ORF Size: 1182 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003779.2, NP_003770.1
• RefSeq Size: 1949
• RefSeq ORF: 1182
• Locus ID: 8703
• Domains: Galactosyl_T_2
• Protein Families: Transmembrane
• Protein Pathways: Glycosphingolipid biosynthesis - lacto and neolacto series, Keratan sulfate biosynthesis, Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) lacks an internal segment in the 5' UTR, and encodes the same protein, as compared to variant 1.