NDE1 (NM_017668) Human Untagged Clone

CAT#: SC320194

NDE1 (untagged)-Human nudE nuclear distribution gene E homolog 1 (A. nidulans) (NDE1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NDE1
• Synonyms: HOM-TES-87; LIS4; MHAC; NDE; NUDE; NUDE1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017668.1 GCACCGCCCTTCGCAGCCGCCTCTGCCGCCGCCGCCGCGTTGGCCTCGCCGCCCCTGCTC
  GGACACCATGCCACAAGGAGAGTGATCTCTTCCCCTGTTTTCACAATGGAGGACTCCGGA
  AAGACTTTCAGCTCCGAGGAGGAAGAAGCTAACTATTGGAAAGATCTGGCGATGACCTAC
  AAACAGAGGGCAGAAAATACGCAAGAGGAACTCCGAGAATTCCAGGAGGGAAGCCGAGAA
  TATGAAGCTGAATTGGAGACGCAGCTGCAACAAATTGAAACCAGGAACAGAGACCTCCTG
  TCCGAAAATAACCGCCTTCGCATGGAGCTGGAAACCATCAAGGAGAAGTTTGAAGTGCAG
  CACTCTGAAGGCTACCGGCAGATCTCAGCCTTGGAGGATGACCTCGCGCAGACCAAAGCC
  ATTAAAGACCAATTGCAGAAATACATCAGAGAGCTGGAGCAAGCAAATGACGACCTGGAA
  AGAGCCAAGCGCGCCACGATCATGTCTCTCGAAGACTTTGAGCAGCGCTTGAATCAGGCC
  ATCGAAAGAAATGCCTTCCTGGAAAGTGAACTTGATGAAAAAGAGAATCTCCTGGAATCT
  GTTCAGAGACTGAAGGATGAAGCCAGAGATTTGCGGCAGGAACTGGCCGTGCAGCAGAAG
  CAGGAGAAACCCAGGACCCCCATGCCCAGCTCAGTGGAAGCTGAGAGGACAGACACAGCT
  GTGCAGGCCACGGGCTCCGTGCCGTCCACGCCCATTGCTCACCGAGGACCCAGCTCAAGT
  TTAAACACACCTGGGAGCTTCAGACGTGGCCTGGACGACTCCACCGGGGGGACCCCCCTC
  ACACCTGCGGCCCGGATATCAGCCCTCAACATTGTGGGAGACCTACTGCGGAAAGTCGGG
  GCACTGGAGTCCAAACTCGCTTCCTGCCGGAACCTCGTGTACGATCAGTCCCCAAACCGA
  ACAGGTGGCCCAGCCTCTGGGCGGAGCAGCAAGAACAGAGATGGCGGGGAGAGACGGCCA
  AGCAGCACCAGCGTGCCTTTGGGTGATAAGGGGTTGGACACGAGTTGCCGCTGGTTGTCC
  AAATCAACAACCAGGTCGTCCAGCTCCTGCTGAAGCCTGTTCTTGGTCTTTTCCAGTTTA
  TCATAAGCGGCCGCCTTCTCCTCGTACTGCTGGGTGAGGTTCTCGATCTCCTTCTGGAAC
  CTCTTCTTCCCCTCTTCCAGAGCTTCCACGGTGCTGGCAAAGTCCTGCAGCTTCTTCTTC
  GAGTCGGAGAGCTACAAGGACAGCGTCCAGGGTAGGGTGAGAGGGGGACCATGAGTGGCC
  CCTGTCCCTGGCCCCACAGACTCTGAGAAGCGAAGACCATGTCTCCTCGTTGGAGAAACC
  CAATAGCAGGGGAAGCTGGGGGGTCAAGCACCATCGCACCAACACTCCACCGCGATCTGC
  CTGCGGGGGATCTCAGCGCAGAGAAGTTGAGAGGACCCATGAAGGAAGCAAGGACACGGG
  GCAGGCACCTGGATGTTGAGAGTGGAGATGTGGCGCTCCAGGTTCTGCTTGGCCTCCATC
  TCCTCGTCCAGCTGGTCTTGCAGGCTGTTCCGCTCCTCCTCCAGCTGGCGCAGCTTCGTA
  GACACGTTGAGCTTCTGCCGGGTTTCTTCTTGAAGCAGCTCCTGCAAAAGGGATGCAAAG
  AGGTCCCAGGGACCTGCCCCGAGGAAGGCCACCCCCCAGGTCCCCTGGATGATGTGGCAG
  GACACTCACCTGGGTGTCCTGGAGCTGGGAACTGAGGGACGCCACGTCCTTGGCCAGCTT
  AATGGCCTTCCCCTCGGCCTCGTTAAGCATCCCTGTGACGCTCTCAACTTCATTCTAAGG
  GTGCCAAGAGACTGGTTAGTCAAAGCCTCTAGAAGGGGATCCTCGTTGAAAGGAGCCCTT
  TTTACTCAAAACACATGGGCTAGTACTTGAGGTGTTCACTGATTGAGAAAATACCCGTGA
  GGTATGGGACTCTGATAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017668.1 unedited
  GGACATTTGTAGTACGACTCCTATAGGGCGGCCGGGACAATTCGTCGACTGGATCCGGTA
  CCGAGGAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGG
  ACCGACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTG
  TAAAACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCG
  GCACGAGGGCACCGCCCTTCGCAGCCGCCTCTGCCGCCGCCGCCGCGTTGGCCTCGCCGC
  CCCTGCTCGGACACCATGCCACAAGGAGAGTGATCTCTTCCCCTGTTTTCACAATGGAGG
  ACTCCGGAAAGACTTTCAGCTCCGAGGAGGAAGAAGCTAACTATTGGAAAGATCTGGCGA
  TGACCTACAAACAGAGGGCAGAAAATACGCAAGAGGAACTCCGAGAATTCCAGGAGGGAA
  GCCGAGAATATGAAGCTGAATTGGAGACGCAGCTGCAACAAATTGAAACCAGGAACAGAG
  ACCTCCTGTCCGAAAATAACCGCCTTCGCATGGAGCTGGAAACCATCAAGGAGAAGTTTG
  AAGTGCAGCACTCTGAAGGCTACCGGCAGATCTCAGCCTTGGAGGATGACCTCGCGCAGA
  CCAAAGCCATTAAAGACCAATTGCAGAAATACATCAGAGAGCTGGAGCAAGCAAATGACG
  ACCTGAAAGAGCCAAGCGCGCCACGATCATGTCTCTCGAAGACTTTGAGCAGCGCTTGAA
  TCAGGCCATCGAAAGAATGCCTTCCTGGAAAGTGAACTTGATGAAAAAGAGATCTCCTGA
  TCTGTTCAGAGACTGAAGGATGAAGCCAGAGATTGCGGCAGGAACTGCCGTGCAGCAGAG
  CAGAGAAACCCAGGACCCCCATGCCCCAGCCTCAGTGGAAGCTGGAGAGGAC
• Restriction Sites: Please inquire
• ACCN: NM_017668
• ORF Size: 1008 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017668.1, NP_060138.1
• RefSeq Size: 1997
• RefSeq ORF: 1008
• Locus ID: 54820
• Domains: NUDE_C
• Gene Summary: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.