PEX19 (NM_002857) Human Untagged Clone

CAT#: SC320225

PEX19 (untagged)-Human peroxisomal biogenesis factor 19 (PEX19), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX19
• Synonyms: D1S2223E; HK33; PBD12A; PMP1; PMPI; PXF; PXMP1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002857.2 AGATGGCCGCCGCTGAGGAAGGCTGTAGTGTCGGGGCCGAAGCGGACAGGGAATTGGAGG
  AGCTTCTGGAAAGTGCTCTTGATGATTTCGATAAAGCCAAACCCTCCCCAGCACCCCCTT
  CTACCACCACGGCCCCTGATGCTTCGGGGCCCCAGAAGAGATCGCCAGGAGACACTGCCA
  AAGATGCCCTCTTCGCTTCCCAAGAGAAGTTTTTCCAGGAACTATTCGACAGTGAACTGG
  CTTCCCAAGCCACTGCGGAGTTCGAGAAGGCAATGAAGGAGTTGGCTGAGGAAGAACCCC
  ACCTGGTGGAGCAGTTCCAAAAGCTCTCAGAGGCTGCAGGGAGAGTGGGCAGTGATATGA
  CCTCCCAACAAGAATTCACTTCTTGCCTAAAGGAAACACTAAGTGGATTAGCCAAAAATG
  CCACTGACCTTCAGAACTCCAGCATGTCGGAAGAAGAGCTGACCAAGGCCATGGAGGGGC
  TAGGCATGGACGAAGGGGATGGGGAAGGGAACATCCTCCCCATCATGCAGAGTATTATGC
  AGAACCTACTCTCCAAGGATGTGCTGTACCCATCACTGAAGGAGATCACAGAAAAGTATC
  CAGAATGGTTGCAGAGTCATCGGGAATCTCTACCTCCAGAGCAGTTTGAAAAATATCAGG
  AGCAGCACAGCGTCATGTGCAAAATATGTGAGCAGTTTGAGGCAGAGACCCCCACAGACA
  GTGAAACCACTCAAAAGGCTCGTTTTGAGATGGTGCTGGATCTTATGCAGCAGCTACAAG
  ATTTAGGCCATCCTCCAAAAGAGCTGGCTGGAGAGATGCCTCCTGGCCTCAACTTTGACC
  TGGATGCCCTCAATCTTTCGGGCCCACCAGGTGCCAGTGGTGAACAGTGTCTGATCATGT
  GAAACACAACACGTTTTCCTCTCTGAGTCCCAGCTATGGGGAACATCTGGAGTCAGCAGA
  ACCATTGGGACCTGAGGCAGGAGTGTCACCTGCGGGAGAAGTCTGCCCGCTGCCCTCTGT
  CATCCCATTCAAGATTGTGCCATACCAGCTGAGGTTTTTCCTCTGTCTCTCTAGGAATAG
  GGTCTGTTTCACAGGCCATTTCTGTGAACCCTACTCCATTGTGGTTTCTGCCACTATCAA
  AGTTCCAGCTACCTGCAAGGTGAAGGAAGGCATCCCTTTTGGGGCATGCACTTTCTTTCC
  TTTCTCAAAATAATGTTATATGTGGCCACACTGATGTTCACCTTTACGTCCAGGGTCTTT
  GTGCCTTGTCTCTACTCCCTCTCTTGGATCTGGGGAGGAGGGGCAGAGACCTGGGACTCT
  GTATTTCTATAGTTCTCCTGGCAGAGCCTTTGAGAATGGGGAGAAACAGCCTGGGCTGGG
  GCTACAGGTCTGTCACTATGCTCTCTTGCCTTCAGACAGACCATTCTGAATTCTCTAAAG
  GGAAAGGGCTTTTGCATCTAATCACAATAGAGTTGAAAGAGAGGCCTTAGGATTCTCCTC
  TCTCTAGGTGCTGAGCCCTCACCTCCCTGTTCCAGGCTGAGAACTCAAATGGTTACCCTG
  CTTCTTCCTACAATGCTGTGTGATATGGGTGAACCCAGCCCCTGACCTTCCTCTATCCCC
  TGCCCATCCTCCCTTTTACCTCCTCTCTTTTTTAAACACCTGTTTATCCCAACCTTTTTG
  AGCTCAAGCTGTGATAAAGAAGGGCCCATCCTATTTCCCCTCATCTAGTCCATTTACGAT
  TCTCACTGACTCCCCGTCTTCCTGGCAGACACAAATAAACCCAGTGTCAGGTCTAGGAAA
  TTAATGGCTATTCTTCCCCAGATACATTCTGGCTTATTTGAGATACATGATTCTCTTAGA
  ATCCTGTCCCTTGGTTCAGGAAAGTAGCTTGGAAAAGGAGTAGGGGTATAGCTTGGGTCC
  CTTTTCCTGCAAGGCCCCATGGGGCAGAATATAATAAATATTCTGAGTGAGGAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_002857
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002857.2, NP_002848.1
• RefSeq Size: 3669 bp
• RefSeq ORF: 900 bp
• Locus ID: 5824
• Cytogenetics: 1q23.2
• Domains: Pex19
• Protein Families: Druggable Genome
• Gene Summary: 'This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]'
  Transcript Variant: This variant (1, also known as PxFall or PEX19all) represents the longest transcript and encodes the longer isoform (a).