PDCD10 (NM_007217) Human Untagged Clone

CAT#: SC320246

PDCD10 (untagged)-Human programmed cell death 10 (PDCD10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDCD10
• Synonyms: CCM3; TFAR15
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_007217.3 GGCCTGGGTGGCGGTAAGGTGTAGCTGTTCTGTCCCAGTCCCCGTAGCTCTGCACCGAGC
  AGAAGAGGTCTAGGGTCACGCAGGGGCCATGGCTGAGGCACTTGGGCTTGGTTCTGGCAG
  GCGGAGCGGACGGGGCTGAGAGCGGGGCCCTACGGGCGGAAGAGGAGCACTGGAAGAAGG
  AAGAGACAAATGTTGGGGTCTACGGATTCAGTTCCAGTTTAATGATGTGGCCCTCTAAGG
  AGATAATTTTGCCTTAAACAGAAAGACTTGACCCTCTTAGGTGTCATACCTAAGATCAGT
  GTGTTTTTTGTGTCCAATTCTTTTATCACCAAAAAAGAGAAGAAATATTGCAGTGAATGA
  AGATTCCTCTGCATTTTAGCACTGCTTTTTCAACTGTAGTTGGCTTTTGAATGAGGATGA
  CAATGGAAGAGATGAAGAATGAAGCTGAGACCACATCCATGGTTTCTATGCCCCTCTATG
  CAGTCATGTATCCTGTGTTTAATGAGCTAGAACGAGTAAATCTGTCTGCAGCCCAGACAC
  TGAGAGCCGCTTTCATCAAGGCTGAAAAAGAAAATCCAGGTCTCACACAAGACATCATTA
  TGAAAATTTTAGAGAAAAAAAGCGTGGAAGTTAACTTCACGGAGTCCCTTCTTCGTATGG
  CAGCTGATGATGTAGAAGAGTATATGATTGAACGACCAGAGCCAGAATTCCAAGACCTAA
  ACGAAAAGGCACGAGCACTTAAACAAATTCTCAGTAAGATCCCAGATGAGATCAATGACA
  GAGTGAGGTTTCTGCAGACAATCAAGGATATAGCTAGTGCAATAAAAGAACTTCTTGATA
  CAGTGAATAATGTCTTCAAGAAATATCAATACCAGAACCGCAGGGCACTTGAACACCAAA
  AGAAAGAATTTGTAAAGTACTCCAAAAGTTTCAGTGATACTCTGAAAACGTATTTTAAAG
  ATGGCAAGGCAATAAATGTGTTCGTAAGTGCCAACCGACTAATTCATCAAACCAACTTAA
  TACTTCAGACCTTCAAAACTGTGGCCTGAAAGTTGTATATGTTAAGAGATGTACTTCTCA
  GTGGCAGTATTGAACTGCCTTTATCTGTAAATTTTAAAGTTTGACTGTATAAATTATCAG
  TCCCTCCTGAAGGGATCTAATCCAGGATGTTGAATGGGATTATTGCCATCTTACACCATA
  TTTTTGTAAAATGTAGCTTAATCATAATCTCACACTGAAGATTTTGCATCACTTTTGCTA
  TTATCATTCTTTTAAGAATTATAAGCCAAAAGAATTTACGCCTTAATGTGTCATTATATA
  ACATTCCTTAAAAGAATTGTAAATATTGGTGTTTGTTTCTGACATTTTAACTTGAAAGCG
  ATATGCTGCAAGATAATGTATTTAACAATATTTGGTGGCAAATATTCAATAAATAGTTTA
  CATCTGTTAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007217.3 unedited
  TGGCGCGAGCTATATGTGTGCCTACTACTACCCGGCGGCCGGGAATTCGTCGACTGGATC
  CGGTACCGAGGAGTATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGT
  TAGCGGACCGACGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCA
  GGCTTGTAAAACGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCG
  GTAAGGTGTAGCTGTTCTGTCCCAGTCCCCGTAGCTCTGCACCGAGCAGAAGAGGTCTAG
  GGTCACGCAGGGGCCATGGCTGAGGCACTTGGGCTTGTTTCTGGCAGGCGGAGCGGACGG
  GGCTGAGAGCGGGGCCCTACGGGCGGAAGAGGAGCACTGGAAGAAGGAAGAGACAAATGT
  TGGGGTCTACGGATTCAGTTCCAGTTTAATGATGTGGCCCTCTAAGGAGATAATTTTGCC
  TTAAACAGAAAGACTTGACCCTCTTAGGTGTCATACCTAAGATCAGTGTGTTTTTTGTGT
  CCAATTCTTTTATCACCAAAAAAGAGAAGAAATATTGCAGTGAATGAAGATTCCTCTGCA
  TTTTAGCACTGCTTTTTCAACTGTAGTTGGCTTTTGAATGAGGATGACAATGGAAGAGAT
  GAAGAATGAAGCTGAGACCACATCCATGGTTTCTATGCCCCTCTATGCAGTCATGTATCC
  TGTGTTTAATGAGCTAGAACGAGTAAATCTGTCTGCAGCCCAGACACTGAGAGCCGCTTT
  CATCAAAGCTGAAAAAGAAAAATCCAGGTCCTCCACCAGACATCATTATGAAATTTTAGA
  AGAAAAAAGCGTGGAAGTTAACTTCACGAGTCCCTCTTCGTTATGGCAGCTGATGATGTA
  AAAGAAGTATATGATGACGACCAGAAGCCCAGAATTCCAGGACCTAACCGATAGGGCCCG
  AGCCACTA
• Restriction Sites: Please inquire
• ACCN: NM_007217
• ORF Size: 639 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007217.3, NP_009148.2
• RefSeq Size: 1454
• RefSeq ORF: 639
• Locus ID: 11235
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same isoform.