PDLIM7 (NM_005451) Human Untagged Clone

CAT#: SC320673

PDLIM7 (untagged)-Human PDZ and LIM domain 7 (enigma) (PDLIM7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDLIM7
• Synonyms: LMP1; LMP3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005451.3 CCCAACGAGGCTCCCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCTGGCCAAGCAGGAGC
  CGGCATCATGGATTCCTTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGCTTCCGGCT
  GCAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAA
  AGCGGCGCAGGCCGGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGC
  GGGTAGCCTCACACACATCGAAGCTCAGAACAAGATCCGGGCCTGCGGGGAGCGCCTCAG
  CCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGGCCTCCGCCCCCGC
  CGCGGACCCTCCGCGGTACACCTTTGCACCCAGCGTCTCCCTCAACAAGACGGCCCGGCC
  CTTTGGGGCGCCCCCGCCCGCTGACAGCGCCCCGCAGCAGAATGGACAGCCGCTCCGACC
  GCTGGTCCCAGATGCCAGCAAGCAGCGGCTGATGGAGAACACAGAGGACTGGCGGCCGCG
  GCCGGGGACAGGCCAGTCGCGTTCCTTCCGCATCCTTGCCCACCTCACAGGCACCGAGTT
  CATGCAAGACCCGGATGAGGAGCACCTGAAGAAATCAAGCCAGGTGCCCAGGACAGAAGC
  CCCAGCCCCAGCCTCATCTACACCCCAGGAGCCCTGGCCTGGCCCTACCGCCCCCAGCCC
  TACCAGCCGCCCGCCCTGGGCTGTGGACCCTGCGTTTGCCGAGCGCTATGCCCCGGACAA
  AACGAGCACAGTGCTGACCCGGCACAGCCAGCCGGCCACGCCCACGCCGCTGCAGAGCCG
  CACCTCCATTGTGCAGGCAGCTGCCGGAGGGGTGCCAGGAGGGGGCAGCAACAACGGCAA
  GACTCCCGTGTGTCACCAGTGCCACAAGGTCATCCGGGGCCGCTACCTGGTGGCGCTGGG
  CCACGCGTACCACCCGGAGGAGTTTGTGTGTAGCCAGTGTGGGAAGGTCCTGGAAGAGGG
  TGGCTTCTTTGAGGAGAAGGGCGCCATCTTCTGCCCACCATGCTATGACGTGCGCTATGC
  ACCCAGCTGTGCCAAGTGCAAGAAGAAGATTACAGGCGAGATCATGCACGCCCTGAAGAT
  GACCTGGCACGTGCACTGCTTTACCTGTGCTGCCTGCAAGACGCCCATCCGGAACAGGGC
  CTTCTACATGGAGGAGGGCGTGCCCTATTGCGAGCGAGACTATGAGAAGATGTTTGGCAC
  GAAATGCCATGGCTGTGACTTCAAGATCGACGCTGGGGACCGCTTCCTGGAGGCCCTGGG
  CTTCAGCTGGCATGACACCTGCTTCGTCTGTGCGATATGTCAGATCAACCTGGAAGGAAA
  GACCTTCTACTCCAAGAAGGACAGGCCTCTCTGCAAGAGCCATGCCTTCTCTCATGTGTG
  AGCCCCTTCTGCCCACAGCTGCCGCGGTGGCCCCTAGCCTGAGGGGCCTGGAGTCGTGGC
  CCTGCATTTCTGGGTAGGGCTGGCAATGGTTGCCTTAACCCTGGCTCCTGGCCCGAGCCT
  GGGGCTCCCTGGGCCCTGCCCCACCCACCTTATCCTCCCACCCCACTCCCTCCACCACCA
  CAGCACACCGGTGCTGGCCACACCAGCCCCCTTTCACCTCCAGTGCCACAATAAACCTGT
  ACCCAGCTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005451.3 unedited
  TCGTTGTATACGACTCCTATAGGGCGGCTCGGGAATTCGGCACGAGGCCCAACGAGGCTC
  CCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCTGGCCAAGCAGGAGCCGGCATCATGGAT
  TCCTTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAG
  GACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAAGCGGCGCAGGCC
  GGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACA
  CACATCGAAGCTCAGAACAAGATCCGGGCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGC
  AGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGGCCTCCGCCCCCGCCGCGGACCCTCCG
  CGGTACACCTTTGCACCCAGCGTCTCCCTCAACAAGACGGCCCGGCCCTTTGGGGCGCCC
  CCGCCCGCTGACAGCGCCCCGCAGCAGAATGGACAGCCGCTCCGACCGCTGGTCCCAGAT
  GCCAGCAAGCAGCGGCTGATGGAGAACACAGAGGACTGGCGGCCGCGGCCGGGGACAGGC
  CAGTCGCGTTCCTTCCGCATCCTTGCCCCACCTCACAGGCACCGAGTTCATGCAAGACCC
  GGATGAGGAGCACCTGAAGAAATCAAGCCAGGTGCCCAGGACAGAAGCCCCAGCCCCAGC
  CTCATCTACACCCCAAGGAGCCCTGGCCTGGCGCGTAGCCGCCCCAGCCCTACCAGCCGC
  CCGCCCTGGGCTGTGGACCCTGCGTTGCCGAGCGCTTATGCCCCGGACAAACGAGCACAG
  TGACTGACCGGCACAGGCAGCGCAAGCAAGCGGCTGCAAGAGCCCGCACCCTCCATTGTG
  CAAGCCACTGCCGGAGAGGCGTGCCA
• Restriction Sites: Please inquire
• ACCN: NM_005451
• ORF Size: 1374 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005451.3, NP_005442.2
• RefSeq Size: 1709
• RefSeq ORF: 1374
• Locus ID: 9260
• Domains: PDZ, LIM
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (1).