COL4A3BP (NM_031361) Human Untagged Clone

CAT#: SC320674

COL4A3BP (untagged)-Human collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (COL4A3BP), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COL4A3BP
• Synonyms: CERT; CERTL; COL4A3BP; GPBP; MRD34; STARD11
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_031361.1 AGGAAGATGGCGGCGGTAGCGGAGGTGTGAGTGGACGCGGGACTCAGCGGCCGGATTTTC
  TCTTCCCTTCTTTTCCCTTTTCCTTCCCTATTTGAAATTGGCATCGAGGGGGCTAAGTTC
  GGGTGGCAGCGCCGGGCGCAACGCAGGGGTCACGGCGACGGCGGCGGCGGCTGACGGCTG
  GAAGGGTAGGCTTCCTTCACCGCTCGTCCTCCTTCCTCGCTCCGCTCGGTGTCAGGCGCG
  GCGGCGGCGCGGCGGGCGGACTTCGTCCCTCCTCCTGCTCCCCCCCACACCGGAGCGGGC
  ACTCTTCGCTTCGCCATCCCCCGACCCTTCACCCCGAGGACTGGGCGCCTCCTCCGGCGC
  AGCTGAGGGAGCGGGGGCCGGTCTCCTGCTCGGTTGTCGAGCCTCCATGTCGGATAATCA
  GAGCTGGAACTCGTCGGGCTCGGAGGAGGATCCAGAGACGGAGTCTGGGCCGCCTGTGGA
  GCGCTGCGGGGTCCTCAGTAAGTGGACAAACTACATTCATGGGTGGCAGGATCGTTGGGT
  AGTTTTGAAAAATAATGCTCTGAGTTACTACAAATCTGAAGATGAAACAGAGTATGGCTG
  CAGAGGATCCATCTGTCTTAGCAAGGCTGTCATCACACCTCACGATTTTGATGAATGTCG
  ATTTGATATTAGTGTAAATGATAGTGTTTGGTATCTTCGTGCTCAGGATCCAGATCATAG
  ACAGCAATGGATAGATGCCATTGAACAGCACAAGACTGAATCTGGATATGGATCTGAATC
  CAGCTTGCGTCGACATGGCTCAATGGTGTCCCTGGTGTCTGGAGCAAGTGGCTACTCTGC
  AACATCCACCTCTTCATTCAAGAAAGGCCACAGTTTACGTGAGAAGTTGGCTGAAATGGA
  AACATTTAGAGACATCTTATGTAGACAAGTTGACACGCTACAGAAGTACTTTGATGCCTG
  TGCTGATGCTGTCTCTAAGGATGAACTTCAAAGGGATAAAGTGGTAGAAGATGATGAAGA
  TGACTTTCCTACAACGCGTTCTGATGGTGACTTCTTGCATAGTACCAACGGCAATAAAGA
  AAAGTTATTTCCACATGTGACACCAAAAGGAATTAATGGTATAGACTTTAAAGGGGAAGC
  GATAACTTTTAAAGCAACTACTGCTGGAATCCTTGCAACACTTTCTCATTGTATTGAACT
  AATGGTTAAACGTGAGGACAGCTGGCAGAAGAGACTGGATAAGGAAACTGAGAAGAAAAG
  AAGAACAGAGGAAGCATATAAAAATGCAATGACAGAACTTAAGAAAAAATCCCACTTTGG
  AGGACCAGATTATGAAGAAGGCCCTAACAGTCTGATTAATGAAGAAGAGTTCTTTGATGC
  TGTTGAAGCTGCTCTTGACAGACAAGATAAAATAGAAGAACAGTCACAGAGTGAAAAGGT
  GAGATTACATTGGCCTACATCCTTGCCCTCTGGAGATGCCTTTTCTTCTGTGGGGACACA
  TAGATTTGTCCAAAAGGTTGAAGAGATGGTGCAGAACCACATGACTTACTCATTACAGGA
  TGTAGGCGGAGATGCCAATTGGCAGTTGGTTGTAGAAGAAGGAGAAATGAAGGTATACAG
  AAGAGAAGTAGAAGAAAATGGGATTGTTCTGGATCCTTTAAAAGCTACCCATGCAGTTAA
  AGGCGTCACAGGACATGAAGTCTGCAATTATTTCTGGAATGTTGACGTTCGCAATGACTG
  GGAAACAACTATAGAAAACTTTCATGTGGTGGAAACATTAGCTGATAATGCAATCATCAT
  TTATCAAACACACAAGAGGGTGTGGCCTGCTTCTCAGCGAGACGTATTATATCTTTCTGT
  CATTCGAAAGATACCAGCCTTGACTGAAAATGACCCTGAAACTTGGATAGTTTGTAATTT
  TTCTGTGGATCATGACAGTGCTCCTCTAAACAACCGATGTGTCCGTGCCAAAATAAATGT
  TGCTATGATTTGTCAAACCTTGGTAAGCCCACCAGAGGGAAACCAGGAAATTAGCAGGGA
  CAACATTCTATGCAAGATTACATATGTAGCTAATGTGAACCCTGGAGGATGGGCACCAGC
  CTCAGTGTTAAGGGCAGTGGCAAAGCGAGAGTATCCTAAATTTCTAAAACGTTTTACTTC
  TTACGTCCAAGAAAAAACTGCAGGAAAGCCTATTTTGTTCTAGTATTAACAGTGACTGAA
  GCAAGGCTGTGTGACATTCCATGTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031361.1 unedited
  GCGTTGTATACGACTCCTATAGGGCGGCCGGAAATCGGCACGAGGAGGAAGATGGCGGCG
  GTAGCGGAGGTGTGAGTGGACGCGGGACTCAGCGGCCGGATTTTCTCTTCCCTTCTTTTC
  CCTTTTCCTTCCCTATTTGAAATTGGCATCGAGGGGGCTAAGTTCGGGTGGCAGCGCCGG
  GCGCAACGCAGGGGTCACGGCGACGGCGGCGGCGGCTGACGGCTGGAAGGGTAGGCTTCC
  TTCACCGCTCGTCCTCCTTCCTCGCTCCGCTCGGTGTCAGGCGCGGCGGCGGCGCGGCGG
  GCGGACTTCGTCCCTCCTCCTGCTCTCCCCCACACCGGAGCGGGCACTCTTCGCTTCGCC
  ATCCCCCGACCCTTCACCCCGAGGACTGGGCGCCTCCTCCGGCGCAGCTGAGGGAGCGGG
  GGCCGGTCTCCTGCTCGGTTGTCGAGCCTCCATGTCGGATAATCAGAGCTGGAACTCGTC
  GGGCTCGGAGGAGGATCCAGAGACGGAGTCTGGGCCGCCTGTGGAGCGCTGCGGGGTCCT
  CAGTAAGTGGACAAACTACATTCATGGGTGGCAGGATCGTTGGGTAGTTTTGAAAAATAA
  TGCTCTGAGTTACTACAAATCTGAAGATGAAAACAGAGTATGGCTGCAGAGGATCCATCT
  GTCTTAGCAAGGCTGTCATCACACCTCACGATTTTGATGAATGTCGATTTGATATTAGTG
  TAAATGATAGTGTATGGTATCTTCGTGCTCAGATCCGGATCATACACAGCCATTGATAAG
  ATGCCCATTGAACAGCACACGACTGAATCTGATATGAATCTGAATTCCAGCTTTGCGTCG
  ACATGGGCTCAATGCTGTCCCTGGGGGTCTGGAGACGAGGTGGCTACTCTGAACAATCCC
  CTCTCTCCTCATAATCGCCCACTGTTTCACCTTGAAAATTTGCTGAAATGGGAAACACTT
  TGGGAG
• Restriction Sites: Please inquire
• ACCN: NM_031361
• ORF Size: 1797 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_031361.1, NP_112729.1
• RefSeq Size: 2311
• RefSeq ORF: 1797
• Locus ID: 10087
• Domains: PH, START
• Gene Summary: This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding region and lacks an alternate in-frame exon compared to variant 3. The resulting isoform (2) is shorter at the N-terminus and lacks an internal segment compared to isoform 3. The absence of the in-frame exon results in the loss of a protein motif and less phosphorylation activity. This isoform also mediates intracellular transport of ceramide from the endoplasmic reticulum to the Golgi apparatus. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.