Calpain 10 (CAPN10) (NM_023083) Human Untagged Clone

CAT#: SC320709

CAPN10 (untagged)-Human calpain 10 (CAPN10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CAPN10
• Synonyms: CANP10; NIDDM1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_023083.2 CACCTGCGGGGCCCTCGGGCTTGGAGGGCTGGGCCGGGCGGGGAACGGGCGGGGCGGGCC
  GGAGGCGGCGGCGGCTGACTCGCCTTCTCTCCGGGGCTGCGACCCCGAGGCAACCGGCTG
  CAGATGGGAGCCCGCGGAGCCGAGGATGCGGGCGGGCCGGGGCGCGACGCCGGCGAGGGA
  GCTGTTCCGGGACGCCGCCTTCCCCGCCGCGGACTCCTCGCTCTTCTGCGACTTGTCTAC
  GCCGCTGGCCCAGTTCCGCGAGGACATCACGTGGAGGCGGCCCCAGGAGATTTGTGCCAC
  ACCCCGGCTGTTTCCAGATGACCCACGGGAAGGGCAGGTGAAGCAGGGGCTGCTGGGGGA
  TTGCTGGTTCCTGTGTGCCTGCGCCGCGCTGCAGAAGAGCAGGCACCTCCTGGACCAGGT
  CATTCCTCCGGGACAGCCGAGCTGGGCCGACCAGGAGTACCGGGGCTCCTTCACCTGTCG
  CATTTGGCAGTTTGGACGCTGGGTGGAGGTGACCACAGATGACCGCCTGCCGTGCCTTGC
  AGGGAGACTCTGTTTCTCCCGCTGCCAGAGGGAGGATGTGTTCTGGCTCCCCTTACTGGA
  AAAGGTCTACGCCAAGGTCCATGGGTCCTACGAGCACCTGTGGGCCGGGCAGGTGGCGGA
  TGCCCTGGTGGACCTGACCGGCGGCCTGGCAGAAAGATGGAACCTGAAGGGCGTAGCAGG
  AAGCGGAGGCCAGCAGGACAGGCCAGGCCGCTGGGAGCACAGGACTTGTCGGCAGCTGCT
  CCACCTGAAGGACCAGTGTCTGATCAGCTGCTGCGTGCTCAGCCCCAGAGCAGGTGCCCG
  GGAGCTGGGGGAGTTCCATGCCTTCATTGTCTCGGACCTGCGGGAGCTCCAGGGTCAGGC
  GGGCCAGTGCATCCTGCTGCTGCGGATCCAGAACCCCTGGGGCCGGCGGTGCTGGCAGGG
  GCTCTGGAGAGAGGGGGGTGAAGGGTGGAGCCAGGTAGATGCAGCGGTAGCATCTGAGCT
  CCTGTCCCAGCTCCAGGAAGGGGAGTTCTGGGTGGAGGAGGAGGAGTTCCTCAGGGAGTT
  TGACGAGCTCACCGTTGGCTACCCGGTCACGGAGGCCGGCCACCTGCAGAGCCTCTACAC
  AGAGAGGCTGCTCTGCCATACGCGGGCGCTGCCTGGGGCCTGGGTCAAGGGCCAGTCAGC
  AGGAGGCTGCCGGAACAACAGCGGCTTTCCCAGCAACCCCAAATTCTGGCTGCGGGTCTC
  AGAACCGAGTGAGGTGTACATTGCCGTCCTGCAGAGATCCAGGCTGCACGCGGCGGACTG
  GGCAGGCCGGGCCCGGGCACTGGTGGGTGACAGTCATACTTCGTGGAGCCCAGCGAGCAT
  CCCGGGCAAGCACTACCAGGCTGTGGGTCTGCACCTCTGGAAGGTAGAGAAGCGGCGGGT
  CAATCTGCCTAGGGTCCTGTCCATGCCCCCCGTGGCTGGCACCGCGTGCCATGCATACGA
  CCGGGAGGTCCACCTGCGTTGTGAGCTCTCACCGGGCTACTACCTGGCTGTCCCCAGCAC
  CTTCCTGAAGGACGCGCCAGGGGAGTTCCTGCTCCGAGTCTTCTCTACCGGGCGAGTCTC
  CCTTAGCGCCATCAGGGCAGTGGCCAAGAACACCACCCCCGGGGCAGCCCTGCCTGCGGG
  GGAGTGGGGGACCGTGCAGCTACGGGGTTCTTGGAGAGTCGGCCAGACGGCGGGGGGCAG
  CAGGAACTTTGCCTCATACCCCACCAACCCCTGCTTCCCCTTCTCGGTCCCCGAGGGCCC
  TGGCCCCCGCTGCGTCCGCATCACTCTGCATCAGCACTGCCGGCCCAGTGACACCGAGTT
  CCACCCCATCGGCTTCCATATCTTCCAGGTCCCAGAGGGTGGAAGGAGCCAGGACGCACC
  CCCACTGCTGCTGCAGGAGCCGCTGCTGAGCTGCGTGCCACATCGCTACGCCCAGGAGGT
  GAGCCGGCTCTGCCTCCTGCCTGCAGGCACCTACAAGGTTGTGCCCTCCACCTACCTGCC
  GGACACAGAGGGGGCCTTCACAGTGACCATCGCAACCAGGATTGACAGGCCATCCATTCA
  CAGCCAGGAGATGCTGGGCCAGTTCCTCCAAGAGGTCTCCGTCATGGCAGTGATGAAAAC
  CTAACAGGGTGGCCCCCTGTGCCAGCTCAGGTGACTGGAGCCCGAGGGCCTGACAGGTTC
  CCAGCAGCTGGGCCGGCCAGCCTTGCACTGTGGGGGCTGGTCCTGAGTCTTGGCCTGCCT
  CCCAGCCCTGCCAGGGGGCTGCGGCCTAGGGGTCCACGGGAAGCCTCCGTCAGGAGAGAC
  GCAGCCCTGGGGGCCAGCTGGTGCTGCAAGGAAGGGTGGGAAGCTTGCTGGCTTCTGTTG
  CGCCACTGAGACGGCAGAGACCCCAGGATCCCAGAGCTTCCCAGGATCCCTCCCAGATCC
  TCTGCTGACTCCATATGGAGGCCTCACACCCAGAGGGTAGGGCAGCAGATCTTCTTTATA
  ACTATTTATTGTTCGAATCACTTTTAGGATGTAACTTTATAAATAAACATGAGCGCTGAT
  GATTTGCAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_023083.2 unedited
  GCCATTGTATACGACTCCTATAGGGCGGCGCGGGAATTCGGCACGAGGCACCTGCGGGGC
  CCTCGGGCTTGGAGGGCTGGGCCGGGCGGGGAACGGGCGGGGCGGGCCGGAGGCGGCGGC
  GGCTGACTCGCCTTCTCTCCGGGGCTGCGACCCCGAGGCAACCGGCTGCAGATGGGAGCC
  CGCGGAGCCGAGGATGCGGGCGGGCCGGGGCGCGACGCCGGCGAGGGAGCTGTTCCGGGA
  CGCCGCCTTCCCCGCCGCGGACTCCTCGCTCTTCTGCGACTTGTCTACGCCGCTGGCCCA
  GTTCCGCGAGGACATCACGTGGAGGCGGCCCCAGGAGATTTGTGCCACACCCCGGCTGTT
  TCCAGATGACCCACGGGAAGGGCAGGTGAAGCAGGGGCTGCTGGGGGATTGCTGGTTCCT
  GTGTGCCTGCGCCGCGCTGCAGAAGAGCAGGCACCTCCTGGACCAGGTCATTCCTCCGGG
  ACAGCCGAGCTGGGCCGACCAGGAGTACCGGGGCTCCTTCACCTGTCGCATTTGGCAGTT
  TGGACGCTGGGTGGAGGTGACCACAGATGACCGCCTGCCGTGCCTTGCAGGGAGACTCTG
  TTTCTCCCGCTGCCAGAGGGAGGATGTGTTCTGGCTCCCCTTACTGGAAAAGGTCTACGC
  CAAGGTCCATGGGTCCTACGAGCACCTGTGGGCCGGGCAGTGGCGGATGCCTGGTGGACC
  TGACCGGCGGCCCTGCCGAAGATGGAACCTGAAGGCGTACAGAAGCGGAGGCCAGCAGAA
  CAGCCAGCCGCTGGGAGCACAGGACTTGTCGCAGCTGCTCCACCTGAAGGACCATGTCTG
  ATCAGCTGCTGCGTGCTCAGCCCAGAACCAGTGCCAGGAGCTGGGGGGAGTCATGCTTAT
  TGTCTCGGAACTGCGGAACTCAAGTTAAGCGGCAGTGGCATCTGGGTGGTGGGATCCGT
• Restriction Sites: Please inquire
• ACCN: NM_023083
• ORF Size: 2019 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_023083.2, NP_075571.1
• RefSeq Size: 2626
• RefSeq ORF: 2019
• Locus ID: 11132
• Protein Families: Druggable Genome, Protease
• Gene Summary: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010]
  Transcript Variant: This variant (1, also known as CAPN10a) represents the longer transcript and encodes the longer isoform (a).