PIGP (NM_153682) Human Untagged Clone

CAT#: SC320893

PIGP (untagged)-Human phosphatidylinositol glycan anchor biosynthesis, class P (PIGP), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIGP
• Synonyms: DCRC; DCRC-S; DSCR5; DSRC; EIEE55; PIG-P
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_153682.2 GGGGGCTCCCCAGTCGGCGCTTGCGCGGAGAACTCAGCGCTGAGATTGTCTAAAGCCCCA
  GGAAAAATGGTGGAAAATTCACCGTCGCCATTGCCAGAAAGAGCGATTTATGGCTTTGTT
  CTTTTCTTAAGCTCCCAATTTGGCTTCATACTTTACCTCGTGTGGGCCTTTATTCCTGAA
  TCTTGGCTAAACTCTTTAGGTTTAACCTATTGGCCTCAAAAATATTGGGCAGTTGCATTA
  CCTGTCTACCTCCTTATTGCTATAGTAATTGGCTACGTGCTCTTGTTTGGGATTAACATG
  ATGAGTACCTCTCCACTCGACTCCATCCATACAATCACAGATAACTATGCAAAAAATCAA
  CAGCAGAAGAAATACCAAGAGGAGGCCATTCCAGCCTTAAGAGATATTTCTATTAGTGAA
  GTAAACCAAATGTTCTTTCTTGCAGCCAAAGAACTTTACACCAAAAACTGAACTGTGTGT
  AACCATAGTAACACCAAGCACGTATTTATTTATAAGTTTTTGCCATTATAATTTTGACCA
  TAAATTAATTTGACCATCTCTCTTATTAATAGAGAAGTAAAAAATGTAACTTGACCTTCT
  CTTAGATTATGTTCAATGAATATTGTAAATGTTCAAGTATTGTTAATGAATAGAATAAAT
  ACAATATTGCATTCGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153682.2 unedited
  TCGATTGTATACGACTCCTATAGGGCGGCTCGGCTAATTCGGCCATTACGGCCGGGGGCT
  CCCCAGTCGGCGCTTGCGCGGAGAACTCAGCGCTGAGATTGTCTAAAGCCCCAGGAAAAA
  TGGTGGAAAATTCACCGTCGCCATTGCCAGAAAGAGCGATTTATGGCTTTGTTCTTTTCT
  TAAGCTCCCAATTTGGCTTCATACTTTACCTCGTGTGGGCCTTTATTCCTGAATCTTGGC
  TAAACTCTTTAGGTTTAACCTATTGGCCTCAAAAATATTGGGCAGTTGCATTACCTGTCT
  ACCTCCTTATTGCTATAGTAATTGGCTTTGTGCTCTTGTTTGGGATTAACATGATGAGTA
  CCTCTCCACTCGACTCCATCCATACAATCACAGATAACTATGCAAAAAATCAACAGCAGA
  AGAAATACCAAGAGGAGGCCATTCCAGCCTTAAGAGATATTTCTATTAGTGAAGTAAACC
  AAATGTTCTTTCTTGCAGCCAAAGAACTTTACACCAAAAACTGAACTGTGTGTAACCATA
  GTAACACCAAGCACGTATTTATTTATAAGTTTTTGCCATTATAATTTTGACCATAAATTA
  ATTTGACCATCTCTCTTATTAATAGAGAAGTAAAAAATGTAACTTGACCTTCTCTTAGAT
  TATGTTCAATGAATATTGTAAATGTTCAAGTATTGTTAATGAATAGAATAAATACAATAT
  TGCATTCGCAAACAACAAAAAAAAAAAACATTGTCGGCCGCCTCGGCCCTCGAGGTTTAA
  CGGCCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCC
  TCCCATGCTTCTCCTGCCTGAGTTGCACTCCAATGCCCACAGCTTGTCTAATAAATAAGT
  GCATCATTTTGTCTGACATAGGTGTTCCTTCTATAAATATTTACCTTGAG
• Restriction Sites: Please inquire
• ACCN: NM_153682
• ORF Size: 405 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_153682.2, NP_710149.1
• RefSeq Size: 804
• RefSeq ORF: 405
• Locus ID: 51227
• Protein Families: Transmembrane
• Protein Pathways: Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways
• Gene Summary: This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (2) contains a distinct 5' UTR and initiates translation from a downstream start codon, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus compared to isoform 1. Variants 2 and 5 encode the same protein (isoform 2).