COQ2 (NM_015697) Human Untagged Clone

CAT#: SC320968

COQ2 (untagged)-Human coenzyme Q2 homolog, prenyltransferase (yeast) (COQ2), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COQ2
• Synonyms: CL640; COQ10D1; MSA1; PHB:PPT
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015697.6 GCCGGGGAATGACGTCAATCCGAGCTCGTCCCGGCCTCACCAGCGCCATGCTGGGCTCGC
  GAGCCGCGGGGTTCGCGCGGGGCCTGCGGGCTTTGGCACTGGCGTGGCTGCCGGGCTGGC
  GGGGCCGCTCCTTCGCCCTGGCGCGTGCGGCAGGCGCGCCCCACGGTGGTGACTTGCAGC
  CCCCCGCCTGTCCCGAGCCGCGCGGGCGCCAGCTCAGTTTGTCCGCGGCGGCGGTGGTGG
  ACTCTGCGCCCCGCCCCCTGCAGCCGTACTTGCGCCTCATGCGGTTGGACAAGCCCATTG
  GAACCTGGCTTCTGTATTTACCATGTACCTGGAGCATTGGTTTGGCAGCTGAACCAGGTT
  GTTTTCCAGATTGGTACATGCTCTCCCTCTTTGGCACTGGAGCTATTCTGATGCGTGGAG
  CAGGCTGTACTATTAATGACATGTGGGACCAGGACTATGATAAAAAGGTTACAAGAACAG
  CCAATCGTCCAATAGCCGCTGGAGACATTTCAACTTTTCAGTCCTTTGTTTTTCTTGGGG
  GACAGCTAACCCTGGCACTGGGTGTTCTTCTGTGTCTAAATTACTACAGTATAGCTCTGG
  GAGCAGGATCCTTACTTCTTGTCATCACCTACCCACTAATGAAAAGAATTTCATACTGGC
  CTCAACTAGCCTTGGGCTTGACATTTAATTGGGGAGCGTTACTTGGATGGTCTGCTATCA
  AGGGTTCCTGTGATCCATCTGTTTGCCTGCCTCTTTATTTTTCTGGAGTTATGTGGACAC
  TAATATATGACACTATTTATGCCCATCAGGACAAAAGAGATGATGTTTTGATTGGTCTTA
  AGTCAACGGCTCTGCGGTTCGGAGAAAATACCAAGCCGTGGCTCAGCGGCTTCAGTGTTG
  CAATGCTGGGGGCACTGAGCCTAGTGGGTGTGAACAGTGGACAGACTGCTCCCTACTACG
  CTGCCCTGGGTGCTGTAGGAGCCCATCTGACTCACCAGATTTACACTCTAGACATCCACA
  GACCTGAGGATTGTTGGAATAAATTTATCTCCAACCGAACACTGGGACTAATAGTTTTTT
  TAGGGATTGTCCTTGGGAATTTGTGGAAAGAAAAGAAGACAGACAAAACAAAGAAGGGTA
  TAGAGAATAAAATAGAAAATTAATGAATGAAATTTATCTAGGAATTTTTAAAACATTTTT
  TACAAAATATAATTAGATTTGAATACAAAATCTGATACAATATGTTAAAGAATTAAGAAC
  CTGAAGATGAAGATTTAGAGCATATTTACCTGGATTTTACTTATTTGCTAGCAAAATTCC
  CCCTTGTCACAGAAACCAGGGACTCTTCAGGATTTGAGATGGCCTTGAGTATTTTAGTTG
  ATACATTCTTCTGCCCATTATAATTCTCACCTGAAGTTATGGGGATTGCACGGGTTTTGG
  CACTTTAGAAAAAGCCTGATGTGGGTCTTACATAAATGAATGTCTGTATAAGAAAATGGA
  CTCTTTTTTTTAGGGAAAAATAAAAGCAACTATGGCAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015697.6 unedited
  GGCGATTGTATACGACTCCTATAGGGCGGCGCGGCAATTCGGCCATTACGGCCGGGGGCC
  GGGGAATGACGTCAATCCGAGCTCGTCCCGGCCTCACCAGCGCCATGCTGGGCTCGCGAG
  CCGCGGGGTTCGCGCGGGGCCTGCGGGCTTTGGCACTGGCGTGGCTGCCGGGCTGGCGGG
  GCCGCTCCTTCGCCCTGGCGCGTGCGGCAGGCGCGCCCCACGGTGGTGACTTGCAGCCCC
  CCGCCTGTCCCGAGCCGCGCGGGCGCCAGCTCAGTTTGTCCGCGGCGGCGGTGGTGGACT
  CTGCGCCCCGCCCCCTGCAGCCGTACTTGCTTTTTATGCGGTTGGACAAGCCCATTGGAA
  CCTGGCTTCTGTATTTACCATGTACCTGGAGCATTGGTTTGGCAGCTGAACCAGGTTGTT
  TTCCAGATTGGTACATGCTCTCCCTCTTTGGCACTGGAGCTATTCTGATGCGTGGAGCAG
  GCTGTACTATTAATGACATGTGGGACCAGGACTATGATAAAAAGGTTACAAGAACAGCCA
  ATCGTCCAATAGCCGCTGGAGACATTTCAACTTTTCAGTCCTTTGTTTTTCTTGGGGGAC
  AGCTAACCCTGGCACTGGGTGTTCTTCTGTGTCTAAATTACTACAGTATAGCTCTGGGAG
  CAGGATCCTTACTTCTTGTCATCACCTACCCACTAATGAAAAGAATTTCATACTGGCCCT
  CAACTAGCCTTGGCTTGACATTTAATTGGGGAGCGTTACTTGGATGGTCTGCTATTCAAA
  GGTTCCTGTGATCCATCTGTTTGCCTGCCTCTTTATTTTTTCTGGAGTTATGTGGACACC
  TAATATATGACACTATTTTATGCCCATCAGACAAAGAAATGAATGTTTGATTTGTCTTAA
  GTTCACCGCTCTTGCGTTCGGAGAAAAAACCAAGCGTGACTCACCCGGACTCCACTGTGT
  GCAT
• Restriction Sites: Please inquire
• ACCN: NM_015697
• ORF Size: 1155 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015697.6, NP_056512.4
• RefSeq Size: 1657
• RefSeq ORF: 1155
• Locus ID: 27235
• Protein Families: Transmembrane
• Protein Pathways: Ubiquinone and other terpenoid-quinone biosynthesis
• Gene Summary: This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.