COQ2 (NM_015697) Human Untagged Clone

CAT#: SC327846

COQ2 (untagged)-Human coenzyme Q2 homolog prenyltransferase (yeast) (COQ2) nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COQ2
• Synonyms: CL640; COQ10D1; MSA1; PHB:PPT
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015697, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCCCAATTTCACAAGTAAGGATGAGGAAAGGTTCTGCCCACACCGCCGCCCAGCCTGGCAGACTAG
  GATTGCATCCTGCGGGTGCCACTGCGCATGCCTGCCGGGGAATGACGTCAATCCGAGCTCGTCCCGGCCT
  CACCAGCGCCATGCTGGGCTCGCGAGCCGCGGGGTTCGCGCGGGGCCTGCGGGCTGTGGCACTGGCGTGG
  CTGCCGGGCTGGCGGGGCCGCTCCTTCGCCCTGGCGCGTGCGGCAGGCGCGCCCCACGGTGGTGACTTGC
  AGCCCCCCGCCTGTCCCGAGCCGCGCGGGCGCCAGCTCAGTTTGTCCGCGGCGGCGGTGGTGGACTCTGC
  GCCCCGCCCCCTGCAGCCGTACTTGCGCCTCATGCGGTTGGACAAGCCCATTGGAACCTGGCTTCTGTAT
  TTACCATGTACCTGGAGCATTGGTTTGGCAGCTGAACCAGGTTGTTTTCCAGATTGGTACATGCTCTCCC
  TCTTTGGCACTGGAGCTATTCTGATGCGTGGAGCAGGCTGTACTATTAATGACATGTGGGACCAGGACTA
  TGATAAAAAGGTTACAAGAACAGCCAATCGTCCAATAGCCGCTGGAGACATTTCAACTTTTCAGTCCTTT
  GTTTTTCTTGGGGGACAGCTAACCCTGGCACTGGGTGTTCTTCTGTGTCTAAATTACTACAGTATAGCTC
  TGGGAGCAGGATCCTTACTTCTTGTCATCACCTACCCACTAATGAAAAGAATTTCATACTGGCCTCAACT
  AGCCTTGGGCTTGACATTTAATTGGGGAGCGTTACTTGGATGGTCTGCTATCAAGGGTTCCTGTGATCCA
  TCTGTTTGCCTGCCTCTTTATTTTTCTGGAGTTATGTGGACACTAATATATGATACTATTTATGCCCATC
  AGGACAAAAGAGATGATGTTTTGATTGGTCTTAAGTCAACGGCTCTGCGGTTCGGAGAAAATACCAAGCC
  GTGGCTCAGCGGCTTCAGTGTTGCAATGCTGGGGGCACTGAGCCTAGTGGGTGTGAACAGTGGACAGACT
  GCTCCCTACTACGCTGCCCTGGGTGCTGTAGGAGCCCATCTGACTCACCAGATTTACACTCTAGACATCC
  ACAGACCTGAGGATTGTTGGAATAAATTTATCTCCAACCGAACACTGGGACTAATAGTTTTTTTAGGGAT
  TGTCCTTGGGAATTTGTGGAAAGAAAAGAAGACAGACAAAACAAAGAAGGGTATAGAGAATAAAATAGAA
  AATTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_015697
• ORF Size: 1266 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015697.7, NP_056512.5
• RefSeq Size: 1657
• RefSeq ORF: 1266
• Locus ID: 27235
• Protein Families: Transmembrane
• Protein Pathways: Ubiquinone and other terpenoid-quinone biosynthesis
• Gene Summary: This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.